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Q7K6A1 (Q7K6A1_PLAF7) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histone deacetylase PIRNR PIRNR037913
EC=3.5.1.98 PIRNR PIRNR037913
Gene names
Name:PfHDAC1 EMBL CAD51938.1
ORF Names:PFI1260c EMBL CAD51938.1
OrganismPlasmodium falciparum (isolate 3D7)
Taxonomic identifier36329 [NCBI]
Taxonomic lineageEukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania)

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone. PIRNR PIRNR037913

Subcellular location

Nucleus By similarity PIRNR PIRNR037913.

Sequence similarities

Belongs to the histone deacetylase family. HD Type 1 subfamily. PIRNR PIRNR037913

Sequences

Sequence LengthMass (Da)Tools
Q7K6A1 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 40F4BB4A0111AD11

FASTA44951,376
        10         20         30         40         50         60 
MSNRKKVAYF HDPDIGSYYY GAGHPMKPQR IRMTHSLIVS YNLYKYMEVY RPHKSDVNEL 

        70         80         90        100        110        120 
TLFHDYEYID FLSSISLENY REFTYQLKRF NVGEATDCPV FDGLFQFQQS CAGASIDGAS 

       130        140        150        160        170        180 
KLNHHCADIC VNWSGGLHHA KMSEASGFCY INDIVLGILE LLKYHARVMY IDIDVHHGDG 

       190        200        210        220        230        240 
VEEAFYVTHR VMTVSFHKFG DYFPGTGDIT DVGVNHGKYY SVNVPLNDGM TDDAFVDLFK 

       250        260        270        280        290        300 
VVIDKCVQTY RPGAIIIQCG ADSLTGDRLG RFNLTIKGHA RCVEHVRSYN IPLLVLGGGG 

       310        320        330        340        350        360 
YTIRNVSRCW AYETGVVLNK HHEMPDQISL NDYYDYYAPD FQLHLQPSNI PNYNSPEHLS 

       370        380        390        400        410        420 
RIKMKIAENL RHIEHAPGVQ FSYVPPDFFN SDIDDESDKN QYELKDDSGG GRAPGTRAKE 

       430        440 
HSTTHHLRRK NYDDDFFDLS DRDQSIVPY

« Hide

References

[1]"Genome sequence of the human malaria parasite Plasmodium falciparum."
Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. expand/collapse author list , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.
Nature 419:498-511(2002) [PubMed: 12368864] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate 3D7.
[2]"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13."
Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. expand/collapse author list , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G.
Nature 419:527-531(2002) [PubMed: 12368867] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Isolate 3D7.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL844508 Genomic DNA. Translation: CAD51938.1.
RefSeqXP_001352127.1. XM_001352091.1.

3D structure databases

ProteinModelPortalQ7K6A1.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsPFI1260c:mRNA; PFI1260c:pep; PFI1260c.
GeneID813532.
GenomeReviewsGene locus PfHDAC1 in contig AL844508_GR.
KEGGpfa:PFI1260c.
NMPDRfig|36329.1.peg.4481.

Organism-specific databases

EuPathDBEupathDB:PFI1260c.

Phylogenomic databases

GeneTreeEPrGT00050000000357.
HOGENOMHBG396919.
OMAIPEDAPH.
ProtClustDBPTZ00063.

Family and domain databases

InterProIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
Gene3DG3DSA:3.40.800.20. His_deacetylse. 1 hit.
KOK06067.
PANTHERPTHR10625. His_deacetylse. 1 hit.
PfamPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetSearch...

Entry information

Entry nameQ7K6A1_PLAF7
AccessionPrimary (citable) accession number: Q7K6A1
Entry history
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info