Reviewed, UniProtKB/Swiss-Prot Q7K4H4 (Y2982_DROME)

Names and origin

Protein names

Recommended name:
    JmjC domain-containing protein CG2982

Gene names

ORF Names:

CG2982

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	653 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the MINA53/NO66 family. Contains 1 JmjC domain.

Ontologies

Keywords
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 653	653	JmjC domain-containing protein CG2982		PRO_0000348221
Regions
	Domain	300 – 450	151	JmjC
Amino acid modifications
	Modified residue	44	1	Phosphoserine Ref.5
	Modified residue	131	1	Phosphoserine Ref.5
	Modified residue	137	1	Phosphothreonine Ref.4
	Modified residue	138	1	Phosphoserine Ref.5 Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Q7K4H4-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 87A4C50A35578313	FASTA	653	73,098
	10 20 30 40 50 60 MKKATTSAAA KSQGNSKMQK NANNGTAKDK KKPNLDKESN DSNSVSDMLA VTKDQEVHAF 70 80 90 100 110 120 FSKLFDDDAG PSTSKKTQSG SAAAAKTADR KRRLQAEADA NNNDTGKAGK LTKESEATQG 130 140 150 160 170 180 ARATKRKQAR SLGLERTSPI QVNGAALACP LVRKSLPPGE ANSCPQPPKK DPAAVNSLVK 190 200 210 220 230 240 IIKAEPTEEG NNNNDEKETE TIETHKADSV EEGRRVLQWI LFPVQTKVFF KDFWEHTACL 250 260 270 280 290 300 VQRSNPKYFQ SMISFKMLDE ILIRHHLDFT VNVDVTTYKN GKRETLNPEG RALPPAVWGF 310 320 330 340 350 360 YSDGCSIRLL NPSTYLIRLR QVCTVLQEFF HCKVGANLYL TPPNSQGFAP HYDDIEAFVI 370 380 390 400 410 420 QVEGRKRWLL YEPPKKADQL ARISSGNYDQ EQLGKPIIDE VLSAGDVLYF PRGAVHQAIT 430 440 450 460 470 480 EEQQHSLHIT LSVYQQQAYA NLLETLMPMV LKKAVDRSVA LRRGLPLHTF QVLGNAYKGN 490 500 510 520 530 540 DCGSRKQLVE NVQKLVTNYL MPSEDDIDEA VDQMAKKFQH EALPPIVLPS EEVRTVHGAR 550 560 570 580 590 600 SDADEQGNCV CDYKFNKKTS VRLLRANILR LVTESDGSVR IYHHVDNGLD YCKYEPYFME 610 620 630 640 650 ILPEEAKAVE LLISAYPFYL TIDQLPLESS ARKIEVATAL WEHGLLMTEK PFK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: GENOME REANNOTATION.
[3]	"A Drosophila full-length cDNA resource." Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M., Celniker S.E. Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002) [PubMed: 12537569] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Berkeley. Tissue: Embryo.
[4]	"An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells." Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D., Juenger M.A., Eng J.K., Aebersold R., Tao W.A. Mol. Biosyst. 3:275-286(2007) [PubMed: 17372656] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-137 AND SER-138, MASS SPECTROMETRY.
[5]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44; SER-131 AND SER-138, MASS SPECTROMETRY. Tissue: Embryo.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAN09120.1. AY051917 mRNA. Translation: AAK93341.1.
RefSeq	NP_572160.1. NP_726923.1.
UniGene	Dm.76
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q7K4H4.
Genome annotation databases
Ensembl	FBgn0029704. Drosophila melanogaster. [Contig view]
GeneID	31374.
KEGG	dme:Dmel_CG2982.
Organism-specific databases
FlyBase	FBgn0029704. CG2982.
Phylogenomic databases
OMA	Q7K4H4. RGFIHQA.
Family and domain databases
InterPro	IPR013109. Cupin_4. IPR003347. TF_JmjC_AAH. [Graphical view]
PANTHER	PTHR13096. Cupin_4. 1 hit.
Pfam	PF08007. Cupin_4. 1 hit. [Graphical view]
SMART	SM00558. JmjC. 1 hit. [Graphical view]
PROSITE	PS51184. JMJC. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	773313.

Entry information

Entry name

Y2982_DROME

Accession

Primary (citable) accession number: Q7K4H4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	October 3, 2006
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

Drosophila annotation project