Unreviewed, UniProtKB/TrEMBL Q7K4D1 (Q7K4D1_DROME)

Names and origin

Protein names

Submitted name:
    Plenty of SH3s EMBL AAF57833.1
Submitted name:
    LD45365p EMBL AAK93408.1

Gene names

Name:	POSH EMBL AAK93408.1 FlyBase FBgn0040294
ORF Names:	CG4909 FlyBase FBgn0040294, Dmel_CG4909 EMBL AAF57833.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAK93408.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	838 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Contains 4 SH3 domains. RuleBase RU003338V3

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338V3 Zinc-finger RuleBase RU000353V2
Ligand	Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	determination of adult life span Inferred from mutant phenotype. Source: FlyBase
Molecular function	receptor signaling complex scaffold activity Non-traceable author statement. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7K4D1-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 37FEFF5F154663E5	FASTA	838	92,058
	10 20 30 40 50 60 MDEHTLNDLL ECSVCLERLD TTSKVLPCQH TFCRKCLQDI VASQHKLRCP ECRILVSCKI 70 80 90 100 110 120 DELPPNVLLM RILEGMKQNA AAGKGEEKGE ETETQPERAK PQPPAESVAP PDNQLLQLQS 130 140 150 160 170 180 HQQSHQPARH KQRRFLLPHA YALFDFASGE ATDLKFKKGD LILIKHRIDN NWFVGQANGQ 190 200 210 220 230 240 EGTFPINYVK VSVPLPMPQC IAMYDFKMGP NDEEGCLEFK KSTVIQVMRR VDHNWAEGRI 250 260 270 280 290 300 GQTIGIFPIA FVELNAAAKK LLDSGLHTHP FCHPPKQQGQ RALPPVPVID PTVVTESSSG 310 320 330 340 350 360 SSNSTPGSSN SSSTSSSNNC SPNHQISLPN TPQHVVASGS ASVRFRDKGA KEKRHSLNAL 370 380 390 400 410 420 LGGGAPLSLL QTNRHSAEIL SLPHELSRLE VSSSTALKPT SAPQTSRVLK TTVQQQMQPN 430 440 450 460 470 480 LPWGYLALFP YKPRQTDELE LKKGCVYIVT ERCVDGWFKG KNWLDITGVF PGNYLTPLRA 490 500 510 520 530 540 RDQQQLMHQW KYVPQNADAQ MAQVQQHPVA PDVRLNNMLS MQPPDLPPRQ QQATATTTSC 550 560 570 580 590 600 SVWSKPVEAL FSRKSEPKPE TATASTTSSS SSGAVGLMRR LTHMKTRSKS PGASLQQVPK 610 620 630 640 650 660 EAISTNVEFT TNPSAKLHPV HVRSGSCPSQ LQHSQPLNET PAAKTAAQQQ QFLPKQLPSA 670 680 690 700 710 720 STNSVSYGSQ RVKGSKERPH LICARQSLDA ATFRSMYNNA ASPPPPTTSV APAVYAGGQQ 730 740 750 760 770 780 QVIPGGGAQS QLHANMIIAP SHRKSHSLDA SHVLSPSSNM ITEAAIKASA TTKSPYCTRE 790 800 810 820 830 SRFRCIVPYP PNSDIELELH LGDIIYVQRK QKNGWYKGTH ARTHKTGLFP ASFVEPDC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAK93408.1.
[2]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013599 Genomic DNA. Translation: AAF57833.1. AY051984 mRNA. Translation: AAK93408.1.
RefSeq	NP_523776.1.
UniGene	Dm.3323
3D structure databases
HSSP	HSSP built from PDB template 1SEM based on UniProtKB P29355.
ModBase	Search...
Proteomic databases
PRIDE	Q7K4D1.
Genome annotation databases
Ensembl	FBgn0040294. Drosophila melanogaster. [Contig view]
GeneID	36990.
KEGG	dme:Dmel_CG4909.
NMPDR	fig|7227.3.peg.5985.
Organism-specific databases
FlyBase	FBgn0040294. POSH.
Phylogenomic databases
OMA	Q7K4D1. THARTHK.
Gene expression databases
ArrayExpress	Q7K4D1.
Family and domain databases
InterPro	IPR000108. Neu_cyt_fact_2. IPR001452. SH3_domain. IPR018957. Znf_C3HC4_RING-type. IPR001841. Znf_RING. IPR017907. Znf_RING_CS. [Graphical view]
Pfam	PF00018. SH3_1. 4 hits. PF00097. zf-C3HC4. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX.
ProDom	PD000066. SH3. 4 hits. [Graphical view] [Entries sharing at least one domain]
SMART	SM00184. RING. 1 hit. SM00326. SH3. 4 hits. [Graphical view]
PROSITE	PS50002. SH3. 4 hits. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	801383.

Entry information

Entry name

Q7K4D1_DROME

Accession

Primary (citable) accession number: Q7K4D1

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	July 7, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)