Unreviewed, UniProtKB/TrEMBL Q7K3V6 (Q7K3V6_DROME)

Names and origin

Protein names

Recommended name:
    Elongation factor Tu RuleBase RU004061V0

Gene names

ORF Names:

CG12736 EMBL AAL13559.1 FlyBase FBgn0033184, Dmel_CG12736 EMBL AAF59240.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAL13559.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	456 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325V3
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325V3

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	GTP-binding RuleBase RU000323V1 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325V3
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: InterPro GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7K3V6-1 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 5B3C8FCBB688092B	FASTA	456	49,673
	10 20 30 40 50 60 MSGLLPKLWR QCEAGLVRRI SQALIGPGAS QSRWTGTRLL ATSADKNPAP GLRELPHCNV 70 80 90 100 110 120 GTIGHVDHGK TTLTAAITRI QSQKGLAEYL SYDQIDRAPE EKARGITINA CHIGYSTTER 130 140 150 160 170 180 TYAHTDCPGH ADYIKNMISG ASQMDGAILV VAATDGQMPQ TREHLLLAKQ VGIQRIIVFI 190 200 210 220 230 240 NKADLVDQEV LELVEIEMRE MLSDFGFDGV NSPVICGSAL LALREDKSEF GVPSIEKLLE 250 260 270 280 290 300 QCDSYIPTPQ RDISSPFILP IDNAFTVPGR GTVVVGTIKR GTIPRNADAD LLGFNQNLKT 310 320 330 340 350 360 SISDIQIFRK SVPQAQAGEN VGALLRGIKI SAVERGMLLC ATGSEDISNH FEGSMYLLSR 370 380 390 400 410 420 AEGGRVKPML SKYIQQLFSQ TWNVPARIDI VPSEAMLMPG EHGQVRVTLL RKMVMTPGQA 430 440 450 FTIRENGATV ATGMVTQRLP SLDLPKNKLS KVFVDC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL13559.1.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[4]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE013599 Genomic DNA. Translation: AAF59240.1. AY058330 mRNA. Translation: AAL13559.1. BT010319 mRNA. Translation: AAQ23637.1.
RefSeq	NP_610288.1.
UniGene	Dm.4770
3D structure databases
HSSP	HSSP built from PDB template 1EFU based on UniProtKB P02990.
ModBase	Search...
Proteomic databases
PRIDE	Q7K3V6.
Genome annotation databases
Ensembl	FBgn0033184. Drosophila melanogaster. [Contig view]
GeneID	35681.
KEGG	dme:Dmel_CG12736.
NMPDR	fig|7227.3.peg.3667.
Organism-specific databases
FlyBase	FBgn0033184. CG12736.
Phylogenomic databases
OMA	Q7K3V6. ISGASQM.
Gene expression databases
ArrayExpress	Q7K3V6.
Family and domain databases
InterPro	IPR000795. ProtSyn_GTP_bd. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. [Graphical view]
PANTHER	PTHR23115:SF31. Transl_elong_EFTu/EF1A_bac/org. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	794696.

Entry information

Entry name

Q7K3V6_DROME

Accession

Primary (citable) accession number: Q7K3V6

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	July 7, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)