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Protein

Palmitoyltransferase

Gene

CG8314

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG8314Imported, Dmel_CG8314Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0034057. CG8314.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 60HelicalUniRule annotationAdd BLAST25
Transmembranei66 – 86HelicalUniRule annotationAdd BLAST21
Transmembranei165 – 188HelicalUniRule annotationAdd BLAST24
Transmembranei208 – 230HelicalUniRule annotationAdd BLAST23

GO - Cellular componenti

  • Golgi apparatus Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0034057.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0086406.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini122 – 248zf-DHHCInterPro annotationAdd BLAST127

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132259.
KOiK20029.
OMAiCGIVCVV.
OrthoDBiEOG091G0CME.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7K3T4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNYSYSALSP GGSGGFGGVD QHNRCCGNKA WCVKDICGIV CVIMTWLLIL
60 70 80 90 100
FAEFVVMRLI LLPSNYTVFS TINMIIFQAL AFLAFASHIR TMLSDPGAVP
110 120 130 140 150
RGNATKEMIE QMGYREGQMF YKCPKCCSIK PERAHHCSVC QRCIRKMDHH
160 170 180 190 200
CPWVNNCVGE NNQKYFVLFT FYIASISVHT LFLVLTQFAE CVKNDWRTCS
210 220 230 240 250
PYSPPATIFL LLFLTFEGLM FGIFTIIMLA TQLTAILNDQ TGIEQLKKEE
260 270 280 290
ARWAKKSRLK SIQSVFGRFS LAWFSPFTEP SCRTRFNSHF YSV
Length:293
Mass (Da):33,380
Last modified:October 3, 2006 - v1
Checksum:i13EED44AF6D7C832
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58085.1.
AY058364 mRNA. Translation: AAL13593.1.
RefSeqiNP_611070.1. NM_137226.4.
UniGeneiDm.4301.

Genome annotation databases

EnsemblMetazoaiFBtr0087268; FBpp0086406; FBgn0034057.
GeneIDi36757.
KEGGidme:Dmel_CG8314.
UCSCiCG8314-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58085.1.
AY058364 mRNA. Translation: AAL13593.1.
RefSeqiNP_611070.1. NM_137226.4.
UniGeneiDm.4301.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0086406.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0087268; FBpp0086406; FBgn0034057.
GeneIDi36757.
KEGGidme:Dmel_CG8314.
UCSCiCG8314-RA. d. melanogaster.

Organism-specific databases

FlyBaseiFBgn0034057. CG8314.

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00850000132259.
KOiK20029.
OMAiCGIVCVV.
OrthoDBiEOG091G0CME.

Miscellaneous databases

GenomeRNAii36757.

Gene expression databases

BgeeiFBgn0034057.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ7K3T4_DROME
AccessioniPrimary (citable) accession number: Q7K3T4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: April 12, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.