Q7K3M5 (Q7K3M5_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG11107 EMBL AAF59269.1
EC=2.7.7.- EMBL AAF59269.1
EC=3.6.1.3 EMBL AAF59269.1

Submitted name:
GM13272p EMBL AAL13713.1

Gene names

ORF Names:

CG11107 FlyBase FBgn0033160 EMBL AAL13713.1, Dmel_CG11107 EMBL AAF59269.1

Organism

Drosophila melanogaster (Fruit fly) EMBL AAL13713.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	729 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 helicase ATP-binding domain. SAAS SAAS011709 Contains 1 helicase C-terminal domain. SAAS SAAS011709

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Helicase RuleBase RU000452 Hydrolase Nucleotidyltransferase EMBL AAF59269.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nuclear mRNA splicing, via spliceosome Inferred by curator. Source: FlyBase
Cellular component	catalytic step 2 spliceosome Inferred from direct assay. Source: FlyBase precatalytic spliceosome Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP-dependent helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro nucleotidyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7K3M5 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 5C14D4338E6403A8	FASTA	729	82,652
	10 20 30 40 50 60 MSKRRIEVGE TYGSKAKKDP EASSSSAAAA AGTVAQILGG FVPNKQPPTM NPLTNTPYSQ 70 80 90 100 110 120 RYQNLYKKRI ALPVFEYQAD FMRLLSLHQC IVLVGETGSG KTTQIPQWCV DFAVSKGRKG 130 140 150 160 170 180 VSCTQPRRVA AMSVAQRVSE EMDVKLGEEV GYSIRFEDCS TAKTLLKYMT DGMLLREAMS 190 200 210 220 230 240 DPMLDQYQVI LLDEAHERTL ATDILMGVLK EVIRQRSDLK LVVMSATLDA GKFQQYFDNA 250 260 270 280 290 300 PLMKVPGRTH PVEIFYTPEP ERDYLEAAIR TVIQIHMCEE IEGDILMFLT GQEEIEEACK 310 320 330 340 350 360 RIKREIDNLG SEIGELKCIP LYSTLPPNLQ QRIFEPAPPP NANGAIGRKV VVSTNIAETS 370 380 390 400 410 420 LTIDGVVFVI DPGFAKQKVY NPRIRVESLL VSPISKASAQ QRSGRAGRTR PGKCFRLYTE 430 440 450 460 470 480 KAFKNEMQDN TYPEILRSNL GTVVLQLKKL GIDDLVHFDF MDPPAPETLM RALELLNYLA 490 500 510 520 530 540 ALDDDGNLTD LGAVMSEFPL DPQLAKMLIA SCQHNCSNEI LSITAMLSVP QCFVRPNEAK 550 560 570 580 590 600 KAADEAKMRF AHIDGDHLTL LNVYHAFKQS SEDPNWCYEN FINFRSLKSA DNVRQQLARI 610 620 630 640 650 660 MDRFNLRRTS TEFTSKDYYV NIRKALVQGF FMQVAHLERT GYYLTIKDNQ NVQLHPSTCL 670 680 690 700 710 720 DHKPDWVIYN EFVLTTKNYI RTVTDVKPEW LCCLAPQYYD LNNFPQCEAK RQLELLQQRL ETKQYQKGF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013599 Genomic DNA. Translation: AAF59269.1. AY058484 mRNA. Translation: AAL13713.1.
RefSeq	NP_610269.1. NM_136425.2.
UniGene	Dm.4189.
3D structure databases
ProteinModelPortal	Q7K3M5.
SMR	Q7K3M5. Positions 50-721.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7K3M5.
Proteomic databases
PRIDE	Q7K3M5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0088966; FBpp0088040; FBgn0033160.
GeneID	35654.
KEGG	dme:Dmel_CG11107.
NMPDR	fig|7227.3.peg.3621.
UCSC	CG11107-RA. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0033160. CG11107.
Phylogenomic databases
eggNOG	inNOG04141.
GeneTree	EMGT00050000000510.
InParanoid	Q7K3M5.
OMA	VIYNEFV.
OrthoDB	EOG4D254T.
PhylomeDB	Q7K3M5.
Gene expression databases
ArrayExpress	Q7K3M5.
Bgee	Q7K3M5.
Family and domain databases
InterPro	IPR014001. DEAD-like_helicase. IPR011545. DNA/RNA_helicase_DEAD/DEAH_N. IPR011709. DUF1605. IPR007502. Helicase-assoc_dom. IPR001650. Helicase_C. [Graphical view]
KO	K12820.
Pfam	PF00270. DEAD. 1 hit. PF04408. HA2. 1 hit. PF00271. Helicase_C. 1 hit. PF07717. OB_NTP_bind. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00847. HA2. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	794560.

Entry information

Entry name

Q7K3M5_DROME

Accession

Primary (citable) accession number: Q7K3M5

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)