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Protein

Palmitoyltransferase

Gene

CG1407

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG1407Imported, Dmel_CG1407Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033474. CG1407.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 37HelicalUniRule annotationAdd BLAST26
Transmembranei52 – 73HelicalUniRule annotationAdd BLAST22
Transmembranei173 – 197HelicalUniRule annotationAdd BLAST25
Transmembranei217 – 243HelicalUniRule annotationAdd BLAST27

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: FlyBase

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0033474.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 252DHHCInterPro annotationAdd BLAST125

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1315. Eukaryota.
COG5273. LUCA.
GeneTreeiENSGT00880000137864.
OrthoDBiEOG091G0AXR.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
IPR030293. ZDHHC15.
PANTHERiPTHR22883:SF162. PTHR22883:SF162. 1 hit.
PfamiView protein in Pfam
PF01529. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7K2V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNDDHRRRK TPCGFCMAVF KWIPVLFITA VIAWSYYAYV VELCIRNSEN
60 70 80 90 100
RIGMIFMLLF YHLFLTLFMW SYWRTIMTSV GRIPDQWRIP DEEVSRLFRA
110 120 130 140 150
DSPDTQKRIL NNFARDLPVT NRTMNGSVRF CEKCKIIKPD RAHHCSVCSC
160 170 180 190 200
CVLKMDHHCP WVNNCVNFYN YKYFVLFLGY ALVYCLYVAF TSLHDFVEFW
210 220 230 240 250
KVGAGQLNAS GMGRFHILFL FFIAIMFAIS LVSLFGYHIY LVLVNRTTLE
260 270 280 290 300
SFRAPIFRVG GPDKNGYNLG RYANFCEVFG DDWQYWFLPV FSSFGDGKTF
310 320 330
PIRHMEEDTE SLLGYHSDTR IELEEDFLPE PRFQDSIP
Length:338
Mass (Da):39,774
Last modified:October 3, 2006 - v1
Checksum:iA2ADF6D20B150755
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58860.3.
AY060631 mRNA. Translation: AAL28179.1.
RefSeqiNP_610544.1. NM_136700.4.
UniGeneiDm.3930.

Genome annotation databases

EnsemblMetazoaiFBtr0088435; FBpp0087521; FBgn0033474.
FBtr0330325; FBpp0303357; FBgn0033474.
GeneIDi36043.
UCSCiCG1407-RB. d. melanogaster.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ7K2V5_DROME
AccessioniPrimary (citable) accession number: Q7K2V5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: July 5, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported