Q7K119 (Q7K119_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ETS-domain lacking EMBL AAG22259.2

Submitted name:
LD15796p EMBL AAL39588.1
Submitted name:
MAE EMBL AAK56919.1

Gene names

Name:	edl FlyBase FBgn0023214
Synonyms:	mae EMBL AAL39588.1
ORF Names:	CG15085 FlyBase FBgn0023214, Dmel_CG15085 EMBL AAG22259.2

Organism

Drosophila melanogaster (Fruit fly) EMBL AAL39588.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1SV0 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	embryonic pattern specification Inferred from mutant phenotype Ref.2. Source: FlyBase negative regulation of transcription, DNA-dependent Inferred from genetic interaction. Source: FlyBase nuclear export Inferred from direct assay. Source: FlyBase photoreceptor cell development Inferred from mutant phenotype. Source: FlyBase regulation of Ras protein signal transduction Inferred from physical interaction Ref.2. Source: FlyBase regulation of epidermal growth factor receptor signaling pathway Inferred from expression pattern Ref.2. Source: FlyBase regulation of phosphorylation Inferred from direct assay Ref.2. Source: FlyBase sensory organ development Inferred from mutant phenotype. Source: FlyBase
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction Ref.2. Source: FlyBase sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7K119 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: 223FA744AA669D2B	FASTA	177	19,340
	10 20 30 40 50 60 MQVESSYTKY AGRVPPLDLT QVNGGQDLWG GNGGGNNASA RRHLHHPYQM LDKCRGGVTL 70 80 90 100 110 120 ISASSAISST SNSSDDNNNR LMSADDGTTS LLHPLGSDGL PLDPRDWTRA DVWKWLINMA 130 140 150 160 170 VSEGLEVTAE LPQKFPMNGK ALCLMSLDMY LCRVPVGGKM LYRDFRVRLA RAMALLS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila." Baker D.A., Mille-Baker B., Wainwright S.M., Ish-Horowicz D., Dibb N.J. Nature 411:330-334(2001) [PubMed: 11357138] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Derepression by depolymerization; structural insights into the regulation of Yan by Mae." Qiao F., Song H., Kim C.A., Sawaya M.R., Hunter J.B., Gingery M., Rebay I., Courey A.J., Bowie J.U. Cell 118:163-173(2004) [PubMed: 15260987] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.07 ANGSTROMS) OF 94-173.
[4]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[5]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Li P., Liao G., Miranda A., Mungall C.J., Nunoo J. , Pacleb J., Paragas V., Park S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL39588.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE013599 Genomic DNA. Translation: AAG22259.2.
AF358670 mRNA. Translation: AAK56919.1.
AY069443 mRNA. Translation: AAL39588.1.

RefSeq

NP_523786.2. NM_079062.2.

UniGene

Dm.689.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1SV0	X-ray	2.07	C/D	94-173	[»]

ProteinModelPortal

Q7K119.

SMR

Q7K119. Positions 94-174.

ModBase

Search...

Protein-protein interaction databases

IntAct

Q7K119. 1 interaction.

STRING

Q7K119.

Proteomic databases

PRIDE

Q7K119.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblMetazoa

FBtr0086652; FBpp0085834; FBgn0023214.

GeneID

37149.

KEGG

dme:Dmel_CG15085.

UCSC

CG15085-RA. d. melanogaster.

Organism-specific databases

CTD

37149.

FlyBase

FBgn0023214. edl.

Phylogenomic databases

eggNOG

inNOG10751.

GeneTree

EMGT00050000002183.

InParanoid

Q7K119.

OMA

TRADVWK.

OrthoDB

EOG4W0VWZ.

PhylomeDB

Q7K119.

Gene expression databases

ArrayExpress

Q7K119.

Bgee

Q7K119.

Family and domain databases

InterPro

IPR003118. Pointed_dom.
IPR013761. SAM/pointed.
[Graphical view]

Gene3D

G3DSA:1.10.150.50. SAM_type. 1 hit.

Pfam

PF02198. SAM_PNT. 1 hit.
[Graphical view]

SMART

SM00251. SAM_PNT. 1 hit.
[Graphical view]

SUPFAM

SSF47769. SAM_homology. 1 hit.

PROSITE

PS51433. PNT. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

NextBio

802195.

Entry information

Entry name

Q7K119_DROME

Accession

Primary (citable) accession number: Q7K119

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)