Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

RH15778p

Gene

Vamp7

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • SNAP receptor activity Source: FlyBase
  • SNARE binding Source: FlyBase
  • syntaxin binding Source: FlyBase

GO - Biological processi

  • autophagosome maturation Source: FlyBase
  • endocytosis Source: GO_Central
  • endosome to lysosome transport Source: FlyBase
  • exocytosis Source: GO_Central
  • vesicle fusion Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-432720 Lysosome Vesicle Biogenesis
R-DME-432722 Golgi Associated Vesicle Biogenesis
R-DME-8856825 Cargo recognition for clathrin-mediated endocytosis
R-DME-8856828 Clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Submitted name:
RH15778pImported
Submitted name:
Vesicle-associated membrane protein 7, isoform AImported
Submitted name:
Vesicle-associated membrane protein 7, isoform CImported
Gene namesi
Name:Vamp7Imported
ORF Names:CG1599Imported, Dmel_CG1599Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0266186 Vamp7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei189 – 214HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0266186

Interactioni

GO - Molecular functioni

  • SNAP receptor activity Source: FlyBase
  • SNARE binding Source: FlyBase
  • syntaxin binding Source: FlyBase

Protein-protein interaction databases

IntActiQ7JYX5, 25 interactors
STRINGi7227.FBpp0088416

Structurei

3D structure databases

SMRiQ7JYX5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 110LonginInterPro annotationAdd BLAST104
Domaini125 – 185V-SNARE coiled-coil homologyInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili144 – 164Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the synaptobrevin family.SAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0859 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00510000047733
KOiK08515
OMAiKLTYTHG
OrthoDBiEOG091G0MPE

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR001388 Synaptobrevin
PfamiView protein in Pfam
PF13774 Longin, 1 hit
PF00957 Synaptobrevin, 1 hit
PRINTSiPR00219 SYNAPTOBREVN
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

Q7JYX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPILYSVISR GTTVLAKFAE CVGNFAEVTE HIIGRIGVHN HKMTYTHGDY
60 70 80 90 100
LIHYTCENKL VYMCITDNEF ERSRAFLFLA DIKQKFIQTY GLQVATAIAY
110 120 130 140 150
SMNTEFSKIL AQQMVYFSQS REVDTISRVH GQIDELKDIM VKNIDSLRDR
160 170 180 190 200
GEKLELLVNK TENLSNNSVA FRKASRNLAR QMFWKNIRVY VVVGLVITFI
210
VYVIVSMACG GLAWQSCV
Length:218
Mass (Da):24,942
Last modified:October 3, 2006 - v1
Checksum:i11B188A73AF07BAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58892.1
AY071695 mRNA Translation: AAL49317.1
AE013599 Genomic DNA Translation: AHN56053.1
RefSeqiNP_001286255.1, NM_001299326.1
NP_610524.1, NM_136680.4
UniGeneiDm.4879

Genome annotation databases

EnsemblMetazoaiFBtr0089394; FBpp0088416; FBgn0266186
FBtr0346639; FBpp0312219; FBgn0266186
GeneIDi36015
KEGGidme:Dmel_CG1599
UCSCiCG1599-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ7JYX5_DROME
AccessioniPrimary (citable) accession number: Q7JYX5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: March 28, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health