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Protein
Submitted name:

RH15778p

Gene

Vamp7

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • SNAP receptor activity Source: FlyBase
  • SNARE binding Source: FlyBase
  • syntaxin binding Source: FlyBase

GO - Biological processi

  • autophagosome maturation Source: FlyBase
  • endocytosis Source: GO_Central
  • endosome to lysosome transport Source: FlyBase
  • exocytosis Source: GO_Central
  • vesicle fusion Source: FlyBase

Enzyme and pathway databases

ReactomeiR-DME-8856825. Cargo recognition for clathrin-mediated endocytosis.
R-DME-8856828. Clathrin-mediated endocytosis.

Names & Taxonomyi

Protein namesi
Submitted name:
RH15778pImported
Submitted name:
Vesicle-associated membrane protein 7, isoform AImported
Submitted name:
Vesicle-associated membrane protein 7, isoform CImported
Gene namesi
Name:Vamp7Imported
ORF Names:CG1599Imported, Dmel_CG1599Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0266186. Vamp7.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei189 – 214HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0266186.

Interactioni

GO - Molecular functioni

  • SNAP receptor activity Source: FlyBase
  • SNARE binding Source: FlyBase
  • syntaxin binding Source: FlyBase

Protein-protein interaction databases

IntActiQ7JYX5. 25 interactors.
STRINGi7227.FBpp0088416.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 110LonginInterPro annotationAdd BLAST104
Domaini125 – 185V-SNARE coiled-coil homologyInterPro annotationAdd BLAST61

Sequence similaritiesi

Belongs to the synaptobrevin family.SAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
GeneTreeiENSGT00510000047733.
KOiK08515.
OMAiKLTYTHG.
OrthoDBiEOG091G0MPE.

Family and domain databases

InterProiView protein in InterPro
IPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
PfamiView protein in Pfam
PF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiView protein in SMART
SM01270. Longin. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiView protein in PROSITE
PS50859. LONGIN. 1 hit.
PS50892. V_SNARE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7JYX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPILYSVISR GTTVLAKFAE CVGNFAEVTE HIIGRIGVHN HKMTYTHGDY
60 70 80 90 100
LIHYTCENKL VYMCITDNEF ERSRAFLFLA DIKQKFIQTY GLQVATAIAY
110 120 130 140 150
SMNTEFSKIL AQQMVYFSQS REVDTISRVH GQIDELKDIM VKNIDSLRDR
160 170 180 190 200
GEKLELLVNK TENLSNNSVA FRKASRNLAR QMFWKNIRVY VVVGLVITFI
210
VYVIVSMACG GLAWQSCV
Length:218
Mass (Da):24,942
Last modified:October 3, 2006 - v1
Checksum:i11B188A73AF07BAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58892.1.
AY071695 mRNA. Translation: AAL49317.1.
AE013599 Genomic DNA. Translation: AHN56053.1.
RefSeqiNP_001286255.1. NM_001299326.1.
NP_610524.1. NM_136680.4.
UniGeneiDm.4879.

Genome annotation databases

EnsemblMetazoaiFBtr0089394; FBpp0088416; FBgn0266186.
FBtr0346639; FBpp0312219; FBgn0266186.
GeneIDi36015.
KEGGidme:Dmel_CG1599.
UCSCiCG1599-RA. d. melanogaster.

Similar proteinsi

Entry informationi

Entry nameiQ7JYX5_DROME
AccessioniPrimary (citable) accession number: Q7JYX5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: September 27, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported