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Protein
Submitted name:

RH15778p

Gene

Vamp7

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • SNAP receptor activity Source: FlyBase
  • SNARE binding Source: FlyBase
  • syntaxin binding Source: FlyBase

GO - Biological processi

  • autophagosome maturation Source: FlyBase
  • endocytosis Source: GO_Central
  • endosome to lysosome transport Source: FlyBase
  • exocytosis Source: GO_Central
  • vesicle fusion Source: FlyBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
RH15778pImported
Submitted name:
Vesicle-associated membrane protein 7, isoform AImported
Submitted name:
Vesicle-associated membrane protein 7, isoform CImported
Gene namesi
Name:Vamp7Imported
ORF Names:CG1599Imported, Dmel_CG1599Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0266186. Vamp7.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei189 – 21426HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • autolysosome Source: FlyBase
  • integral component of membrane Source: UniProtKB-KW
  • late endosome membrane Source: FlyBase
  • SNARE complex Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiFBgn0033452.

Interactioni

GO - Molecular functioni

  • SNAP receptor activity Source: FlyBase
  • SNARE binding Source: FlyBase
  • syntaxin binding Source: FlyBase

Protein-protein interaction databases

STRINGi7227.FBpp0088416.

Structurei

3D structure databases

SMRiQ7JYX5. Positions 1-184.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 110104LonginInterPro annotationAdd
BLAST
Domaini125 – 18561V-SNARE coiled-coil homologyInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the synaptobrevin family.SAAS annotation
Contains longin domain.SAAS annotation
Contains v-SNARE coiled-coil homology domain.SAAS annotation

Keywords - Domaini

Coiled coilSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
GeneTreeiENSGT00510000047733.
KOiK08515.
OMAiILAQQMV.
OrthoDBiEOG091G0MPE.
PhylomeDBiQ7JYX5.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7JYX5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPILYSVISR GTTVLAKFAE CVGNFAEVTE HIIGRIGVHN HKMTYTHGDY
60 70 80 90 100
LIHYTCENKL VYMCITDNEF ERSRAFLFLA DIKQKFIQTY GLQVATAIAY
110 120 130 140 150
SMNTEFSKIL AQQMVYFSQS REVDTISRVH GQIDELKDIM VKNIDSLRDR
160 170 180 190 200
GEKLELLVNK TENLSNNSVA FRKASRNLAR QMFWKNIRVY VVVGLVITFI
210
VYVIVSMACG GLAWQSCV
Length:218
Mass (Da):24,942
Last modified:October 3, 2006 - v1
Checksum:i11B188A73AF07BAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58892.1.
AY071695 mRNA. Translation: AAL49317.1.
AE013599 Genomic DNA. Translation: AHN56053.1.
RefSeqiNP_001286255.1. NM_001299326.1.
NP_610524.1. NM_136680.4.
UniGeneiDm.4879.

Genome annotation databases

EnsemblMetazoaiFBtr0089394; FBpp0088416; FBgn0266186.
FBtr0346639; FBpp0312219; FBgn0266186.
GeneIDi36015.
KEGGidme:Dmel_CG1599.
UCSCiCG1599-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58892.1.
AY071695 mRNA. Translation: AAL49317.1.
AE013599 Genomic DNA. Translation: AHN56053.1.
RefSeqiNP_001286255.1. NM_001299326.1.
NP_610524.1. NM_136680.4.
UniGeneiDm.4879.

3D structure databases

SMRiQ7JYX5. Positions 1-184.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0088416.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0089394; FBpp0088416; FBgn0266186.
FBtr0346639; FBpp0312219; FBgn0266186.
GeneIDi36015.
KEGGidme:Dmel_CG1599.
UCSCiCG1599-RA. d. melanogaster.

Organism-specific databases

CTDi6845.
FlyBaseiFBgn0266186. Vamp7.

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
GeneTreeiENSGT00510000047733.
KOiK08515.
OMAiILAQQMV.
OrthoDBiEOG091G0MPE.
PhylomeDBiQ7JYX5.

Miscellaneous databases

GenomeRNAii36015.
PROiQ7JYX5.

Gene expression databases

BgeeiFBgn0033452.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7JYX5_DROME
AccessioniPrimary (citable) accession number: Q7JYX5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: September 7, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.