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Protein

Phosphotransferase

Gene

Hex-C

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular glucose homeostasis Source: GO_Central
  • glycolytic process Source: GO_Central
  • lateral inhibition Source: FlyBase
  • regulation of glucose metabolic process Source: FlyBase
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DME-170822. Regulation of Glucokinase by Glucokinase Regulatory Protein.
R-DME-70153. Glucose transport.
R-DME-70171. Glycolysis.

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
Name:Hex-CImported
ORF Names:CG8094Imported, Dmel_CG8094Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0001187. Hex-C.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Expressioni

Gene expression databases

BgeeiFBgn0001187.

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0086530.

Structurei

3D structure databases

SMRiQ7JYW9. Positions 1-452.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 200195Hexokinase_1InterPro annotationAdd
BLAST
Domaini207 – 449243Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
KOiK00844.
OMAiIFETKHI.
OrthoDBiEOG091G08MD.
PhylomeDBiQ7JYW9.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7JYW9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDAEVRELM QPFVLSDYQV QEVYSRFCLE VARGLKRSTH PQANVKCFPT
60 70 80 90 100
YVQDLPTGDE MGKYLALDLG GTNFRVLLVS LKGHHDATVD SQIYAVPKDL
110 120 130 140 150
MVGPGVDLFD HIAGCLAKFV EKHDMKTAYL PLGFTFSFPC VQLGLKEGIL
160 170 180 190 200
VRWTKGFDCA GVEGEDVGRM LHEAIQRRGD ADIAVVAILN DTTGTLMSCA
210 220 230 240 250
HRNADCRVGV IVGTGCNACY VEDVENVDLL RADFKKTKRS VIVNAEWGAF
260 270 280 290 300
GEGGQLDFVR TEYDREVDEK SLNRSEQLFE KMTAGMYLGN LVRLVLLRAL
310 320 330 340 350
ERKLIFKQSS RRPEFASVLQ RNEEVFETRY ISEIEDDSFP EFASTRKIVK
360 370 380 390 400
NLFGLEKASV EDCQTLRYIC ECVAKRAATL VAIGVSGLVN RTSNRRVIVG
410 420 430 440 450
MDGSVYRYHP KFDAYMRQTL QKLVKADKEW DIMLSEDGSG RGAALVAAVA

SKTK
Length:454
Mass (Da):50,738
Last modified:October 3, 2006 - v1
Checksum:i57B3E6254F63710F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58160.1.
AF237469 mRNA. Translation: AAG10690.1.
AF257540 Genomic DNA. Translation: AAG23064.1.
AF257541 Genomic DNA. Translation: AAG23065.1.
AF257543 Genomic DNA. Translation: AAG23067.1.
AF257546 Genomic DNA. Translation: AAG23070.1.
AF257547 Genomic DNA. Translation: AAG23071.1.
AF257549 Genomic DNA. Translation: AAG23073.1.
AF257551 Genomic DNA. Translation: AAG23075.1.
AF257554 Genomic DNA. Translation: AAG23078.1.
AF257555 Genomic DNA. Translation: AAG23079.1.
AF257558 Genomic DNA. Translation: AAG23082.1.
AF257561 Genomic DNA. Translation: AAG23085.1.
AF257564 Genomic DNA. Translation: AAG23088.1.
AF257565 Genomic DNA. Translation: AAG23089.1.
AF257567 Genomic DNA. Translation: AAG23091.1.
AF257568 Genomic DNA. Translation: AAG23092.1.
AF257570 Genomic DNA. Translation: AAG23094.1.
AF257571 Genomic DNA. Translation: AAG23095.1.
AF257573 Genomic DNA. Translation: AAG23097.1.
AF257574 Genomic DNA. Translation: AAG23098.1.
AF257575 Genomic DNA. Translation: AAG23099.1.
AF257576 Genomic DNA. Translation: AAG23100.1.
AF257577 Genomic DNA. Translation: AAG23101.1.
AF257578 Genomic DNA. Translation: AAG23102.1.
AF257581 Genomic DNA. Translation: AAG23105.1.
AF257582 Genomic DNA. Translation: AAG23106.1.
AF257583 Genomic DNA. Translation: AAG23107.1.
AF257585 Genomic DNA. Translation: AAG23109.1.
AF257587 Genomic DNA. Translation: AAG23111.1.
AF257588 Genomic DNA. Translation: AAG23112.1.
AF257589 Genomic DNA. Translation: AAG23113.1.
AY070657 mRNA. Translation: AAL48128.1.
AY071719 mRNA. Translation: AAL49341.1.
AJ309864 Genomic DNA. Translation: CAC34564.1.
RefSeqiNP_524674.1. NM_079935.4.
UniGeneiDm.1873.

Genome annotation databases

EnsemblMetazoaiFBtr0087399; FBpp0086530; FBgn0001187.
GeneIDi44008.
KEGGidme:Dmel_CG8094.
UCSCiCG8094-RA. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA. Translation: AAF58160.1.
AF237469 mRNA. Translation: AAG10690.1.
AF257540 Genomic DNA. Translation: AAG23064.1.
AF257541 Genomic DNA. Translation: AAG23065.1.
AF257543 Genomic DNA. Translation: AAG23067.1.
AF257546 Genomic DNA. Translation: AAG23070.1.
AF257547 Genomic DNA. Translation: AAG23071.1.
AF257549 Genomic DNA. Translation: AAG23073.1.
AF257551 Genomic DNA. Translation: AAG23075.1.
AF257554 Genomic DNA. Translation: AAG23078.1.
AF257555 Genomic DNA. Translation: AAG23079.1.
AF257558 Genomic DNA. Translation: AAG23082.1.
AF257561 Genomic DNA. Translation: AAG23085.1.
AF257564 Genomic DNA. Translation: AAG23088.1.
AF257565 Genomic DNA. Translation: AAG23089.1.
AF257567 Genomic DNA. Translation: AAG23091.1.
AF257568 Genomic DNA. Translation: AAG23092.1.
AF257570 Genomic DNA. Translation: AAG23094.1.
AF257571 Genomic DNA. Translation: AAG23095.1.
AF257573 Genomic DNA. Translation: AAG23097.1.
AF257574 Genomic DNA. Translation: AAG23098.1.
AF257575 Genomic DNA. Translation: AAG23099.1.
AF257576 Genomic DNA. Translation: AAG23100.1.
AF257577 Genomic DNA. Translation: AAG23101.1.
AF257578 Genomic DNA. Translation: AAG23102.1.
AF257581 Genomic DNA. Translation: AAG23105.1.
AF257582 Genomic DNA. Translation: AAG23106.1.
AF257583 Genomic DNA. Translation: AAG23107.1.
AF257585 Genomic DNA. Translation: AAG23109.1.
AF257587 Genomic DNA. Translation: AAG23111.1.
AF257588 Genomic DNA. Translation: AAG23112.1.
AF257589 Genomic DNA. Translation: AAG23113.1.
AY070657 mRNA. Translation: AAL48128.1.
AY071719 mRNA. Translation: AAL49341.1.
AJ309864 Genomic DNA. Translation: CAC34564.1.
RefSeqiNP_524674.1. NM_079935.4.
UniGeneiDm.1873.

3D structure databases

SMRiQ7JYW9. Positions 1-452.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7227.FBpp0086530.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0087399; FBpp0086530; FBgn0001187.
GeneIDi44008.
KEGGidme:Dmel_CG8094.
UCSCiCG8094-RA. d. melanogaster.

Organism-specific databases

CTDi44008.
FlyBaseiFBgn0001187. Hex-C.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
GeneTreeiENSGT00390000017159.
KOiK00844.
OMAiIFETKHI.
OrthoDBiEOG091G08MD.
PhylomeDBiQ7JYW9.

Enzyme and pathway databases

ReactomeiR-DME-170822. Regulation of Glucokinase by Glucokinase Regulatory Protein.
R-DME-70153. Glucose transport.
R-DME-70171. Glycolysis.

Miscellaneous databases

GenomeRNAii44008.

Gene expression databases

BgeeiFBgn0001187.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7JYW9_DROME
AccessioniPrimary (citable) accession number: Q7JYW9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 3, 2006
Last sequence update: October 3, 2006
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.