Q7JVY2 (Q7JVY2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Double parked EMBL AAF58141.2

Submitted name:
LD35784p EMBL AAM49924.1
Submitted name:
Replication protein double parked EMBL AAF99080.1

Gene names

Name:	dup EMBL AAM49924.1 FlyBase FBgn0000996
ORF Names:	Dmel_CG8171 EMBL AAF58141.2

Organism

Drosophila melanogaster (Fruit fly) EMBL AAM49924.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	743 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	DNA endoreduplication Inferred from mutant phenotype. Source: FlyBase DNA replication checkpoint Inferred from mutant phenotype Ref.2. Source: FlyBase antimicrobial humoral response Inferred from mutant phenotype. Source: FlyBase centrosome duplication Inferred from mutant phenotype. Source: FlyBase cytokinesis Inferred from mutant phenotype. Source: FlyBase eggshell chorion gene amplification Traceable author statement. Source: FlyBase mitotic sister chromatid separation Inferred from mutant phenotype. Source: FlyBase
Cellular component	cytoplasm Inferred from direct assay Ref.2. Source: FlyBase nuclear origin of replication recognition complex Inferred from direct assay Ref.2. Source: FlyBase replication fork Inferred from direct assay. Source: FlyBase
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7JVY2 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: B7BC712E6D30440B	FASTA	743	83,479
	10 20 30 40 50 60 MAQPSVAAFF TNRKRAALDD AISIKNRRLV EPAETVSPAS APSQLPAGDQ DADLDTLKAA 70 80 90 100 110 120 ATGMRTRSGR TARLIVTAAQ ESKKKTPAAA KMEPHIKQPK LVQFIKKGTL SPRKQAQSSK 130 140 150 160 170 180 LDEEELQQSS AISEHTPKVN FTITSQQNAD NVQRGLRTPT KQILKDASPI KADLRRQLTF 190 200 210 220 230 240 DEVKTKVSRS AKLQELKAVL ALKAALEQKR KEQEERNRKL RDAGPSPSKS KMSVQLKEFD 250 260 270 280 290 300 TIELEVLISP LKTFKTPTKI PPPTPDKHEL MSPRHTDVSK RLLFSPAKNG SPVKLVEVPA 310 320 330 340 350 360 YKRYASLVES SRAGQLPLPY KYRHLLDVFK GLDSVVAMFH NRKETITFKK LKPAVQRMLR 370 380 390 400 410 420 KNFTETHLAQ IKHIYPDAFI FSQVKTRNFG SVSKADYFQL IIAPNVEPLP EQQQSEKPQH 430 440 450 460 470 480 FTKINEDDVL ASAQSTSMNP HVMTARMQRF QSLLLDRAMR AHDQFLRSQD PPIIIEKALT 490 500 510 520 530 540 RWHPQFDLES CPEVELSPLP QPPNVEKYSS AKDILSTARN LFNCATPMER AMDRYEAKLE 550 560 570 580 590 600 SEKQQAAESN KKTEEQQAGE VTRTSTAIQT SQEVPGISGS SKNPTVPETT NQTETAKPTV 610 620 630 640 650 660 KDCTVPDASS NLLKGLPKSL IEKIRAKQAA KALEAMTRRP SQDQEATKYS RLPELARHLR 670 680 690 700 710 720 NVFVTERKGV LTLEVIIKKI QNSFRANLTP QEIEAHLKLL AKELPSWASF HEVRKTMYLK 730 740 VAKDMDMNKI IEKLESVANA KSN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Drosophila double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts." Whittaker A.J., Royzman I., Orr-Weaver T.L. Genes Dev. 14:1765-1776(2000) [PubMed: 10898791] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[4]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM49924.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013599 Genomic DNA. Translation: AAF58141.2. AF279146 mRNA. Translation: AAF99080.1. AY118555 mRNA. Translation: AAM49924.1.
RefSeq	NP_524878.1. NM_080139.4.
UniGene	Dm.1771.
3D structure databases
ProteinModelPortal	Q7JVY2.
SMR	Q7JVY2. Positions 297-503, 607-742.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-20004N.
IntAct	Q7JVY2. 4 interactions.
STRING	Q7JVY2.
Proteomic databases
PRIDE	Q7JVY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0087387; FBpp0086519; FBgn0000996.
GeneID	47121.
KEGG	dme:Dmel_CG8171.
UCSC	CG8171-RA. d. melanogaster.
Organism-specific databases
CTD	13535.
FlyBase	FBgn0000996. dup.
Phylogenomic databases
eggNOG	inNOG04923.
GeneTree	EMGT00050000011553.
InParanoid	Q7JVY2.
OMA	ARNLFNC.
OrthoDB	EOG46WWQR.
PhylomeDB	Q7JVY2.
Gene expression databases
ArrayExpress	Q7JVY2.
Bgee	Q7JVY2.
Family and domain databases
InterPro	IPR014939. CDT1_Gemini-bd-like. [Graphical view]
KO	K10727.
Pfam	PF08839. CDT1. 1 hit. [Graphical view]
SMART	SM01075. CDT1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	838909.

Entry information

Entry name

Q7JVY2_DROME

Accession

Primary (citable) accession number: Q7JVY2

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)