Q7JUM5 (Q7JUM5_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
LD43341p EMBL AAM52699.1

Submitted name:
Microcephalin, isoform B EMBL AAF58605.3

Gene names

Name:	MCPH1 FlyBase FBgn0033664 FlyBase FBgn0260959
ORF Names:	CG8981 FlyBase FBgn0033664 EMBL AAM52699.1, Dmel_CG42572 EMBL AAF58605.3

Organism

Drosophila melanogaster (Fruit fly) EMBL AAM52699.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	826 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	embryo development Inferred from mutant phenotype. Source: FlyBase mitosis Inferred from mutant phenotype. Source: FlyBase mushroom body development Inferred from mutant phenotype. Source: FlyBase pole cell formation Inferred from mutant phenotype. Source: FlyBase
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7JUM5 [UniParc]. Last modified October 3, 2006. Version 1. Checksum: D95B6A7C532572B1	FASTA	826	91,018
	10 20 30 40 50 60 MDKFLLRNPT WKTKTYGSVV ASSAAAAKKT AASSTRRPLH DSNLGDFRSK AAAPSPKSLS 70 80 90 100 110 120 QAPADDQAAR DRLMLKPALA VSKAISQHRS EFHQDENEAG AEGSAAKPDP PIGAATPTRQ 130 140 150 160 170 180 EGHWARLQQD LNSPNAALRL RAIRALKSPT KSAYNTFDVP LAEQSIITME ERNPQEPPSL 190 200 210 220 230 240 PELLKDIVVY VEVRTGNDNR SEGVKSIIAK MGAQVKDRLT RTTTHVVFKD GLLSTYKKAT 250 260 270 280 290 300 EWNIPVVSIL WIEACKVQLK ICDPKQFPIS NIRMYEYPEL FGKMPRVKFM QPDSELNQRP 310 320 330 340 350 360 RKRQGTPTSS KDNEPGSTNK RAQTGTPTTT TPKNDISRFF RAINHNKPSD DEAIESPATK 370 380 390 400 410 420 LLNRISSGCY TPLPAGGTPQ LMGTNGSGDA VAQKVQAQKS LQFGEQTDSN TPQAKPSSTS 430 440 450 460 470 480 RPRRSTVDPP PVMTPPVRTT RRRSCVAEIS SPAATDTRMT RRRSSLLTST VIHEADPTQT 490 500 510 520 530 540 AVAEPRMTRR RSSLLGIAKQ AEETAQRQTI QPITEELAPV EENRNSIIMA ETNIINNTNC 550 560 570 580 590 600 LEQSIEITAV EAEASFKADR RGTLYASELM DISSPRRRSV AKSSLELRQE NLAPRARQSL 610 620 630 640 650 660 SNVTTQTSFL DVEQQVTPLF SSTRLPTGQT TGNRRRTIFN MDMDVINESI ERMNQSHRMS 670 680 690 700 710 720 LALANKAELG ESCQVHEQEP PQAEPVPSQE PKRRRLFNPN DEVVISPAMS NRKSRLSITG 730 740 750 760 770 780 SGSSSSVQKR RRSLATPAKS SSSELCATTP LSKAVTNKEA EKSKSNTEIS EASLDAVPEV 790 800 810 820 KKSTSNAGEE NEKPKGKSRT RIRTLVHTNM HQEQINVIRK VGNTTE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAM52699.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE013599 Genomic DNA. Translation: AAF58605.3. AY122187 mRNA. Translation: AAM52699.1.
RefSeq	NP_610711.1. NM_136867.2.
UniGene	Dm.6585.
3D structure databases
ProteinModelPortal	Q7JUM5.
SMR	Q7JUM5. Positions 182-275.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7JUM5.
Proteomic databases
PRIDE	Q7JUM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0301429; FBpp0290644; FBgn0260959.
GeneID	36272.
KEGG	dme:Dmel_CG42572.
UCSC	CG8981-RB. d. melanogaster.
Organism-specific databases
CTD	79648.
FlyBase	FBgn0260959. MCPH1.
Phylogenomic databases
GeneTree	EMGT00050000014977.
InParanoid	Q7JUM5.
OMA	PRMTRRR.
PhylomeDB	Q7JUM5.
Gene expression databases
ArrayExpress	Q7JUM5.
Bgee	Q7JUM5.
Family and domain databases
InterPro	IPR001357. BRCT. [Graphical view]
SMART	SM00292. BRCT. 1 hit. [Graphical view]
SUPFAM	SSF52113. BRCT. 1 hit.
PROSITE	PS50172. BRCT. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	797665.

Entry information

Entry name

Q7JUM5_DROME

Accession

Primary (citable) accession number: Q7JUM5

Entry history

Integrated into UniProtKB/TrEMBL:	October 3, 2006
Last sequence update:	October 3, 2006
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)