Q7JP25 (Q7JP25_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DmMstProx EMBL AAC46999.1

Gene names

Name:	MstProx EMBL AAC46999.1 FlyBase FBgn0015770
ORF Names:	CG1149 FlyBase FBgn0015770

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	711 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 TIR domain. SAAS SAAS000157

Ontologies

Keywords
Cellular component	Membrane
Domain	Repeat SAAS SAAS000157 Transmembrane Transmembrane helix SAAS SAAS000157
Gene Ontology (GO)
Biological process	innate immune response Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	transmembrane signaling receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7JP25 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 007CD7AEF67BC1B0	FASTA	711	83,176
	10 20 30 40 50 60 MKVRNYIPNK NFTALICTHK NCNFIRGING LECPKLCQCL YIIDDLELNI DCSNLGLLQI 70 80 90 100 110 120 PPLPIPIYGD VKLNFSNNSL SQLPTMTLPG YKLVKRLDVS RNRLTNLSIN HLPAKLDYLD 130 140 150 160 170 180 VSFNEIINMG NDVIKYLRTV PIFKQTGNQW TIHCDDKPLL NFFRHLKLII RMKSAEMKPM 190 200 210 220 230 240 FLHSLTELPK GFLKFLGKHF IWLGVRKQEY YLINEEQLLQ SMHRKLNNLN TIMSIYKYME 250 260 270 280 290 300 WLHRKLIFVN REYDLFYIRQ MAAPCPHKCE CCYSRDSLIL KIDCRNKFVY NFPDIVARNS 310 320 330 340 350 360 RLMRKQNMSS PMELHLSKNN ISNITIAMLP KELRFLDLRF NNLVTLDDKV LSYLKKNSIK 370 380 390 400 410 420 TKLSGNPWNC DCKSRSVLSI LRDHEPLEYD VTLKRCNISP TDCPDVCVCC LDNLTWPSFI 430 440 450 460 470 480 VDCRGEGLLQ MPSLSSRVTY VDLRNNNLTA LSQKNRSSIE NRSLKLHLLD NPWSCSCNDI 490 500 510 520 530 540 EKINFMKSVS SSIVDFTEIK CSNGEKLVSI NQHIVCPSDL FYYLALAISL VATIIALNFL 550 560 570 580 590 600 IWFRQPVLVW FYEHGVCLSL AAKRELDKDK RFDAFLAFTH KDEALLEEFV DRLERGRPRF 610 620 630 640 650 660 QLCFYLRDWL AGESIPDCIG QSIKDSRRII VLMTENFMNS TWGRLEFRLA LHATSRDRCK 670 680 690 700 710 RLIVVLYPNV KNFDSLDSEL RTYMAFNTYL ERSHPNFWNK LIYSMPHTKL R

References

[1]	"T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family." Mitcham J.L., Parnet P., Bonnert T.P., Garka K.E., Gerhart M.J., Slack J.L., Gayle M.A., Dower S.K., Sims J.E. J. Biol. Chem. 271:5777-5783(1996) [PubMed: 8621445] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U42425 Genomic DNA. Translation: AAC46999.1.
3D structure databases
HSSP	HSSP built from PDB template 1O77 based on UniProtKB O60603.
ProteinModelPortal	Q7JP25.
SMR	Q7JP25. Positions 22-155, 280-380, 437-509, 563-709.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7JP25.
Proteomic databases
PRIDE	Q7JP25.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0015770. MstProx.
Phylogenomic databases
InParanoid	Q7JP25.
OrthoDB	EOG4GQNKX.
Gene expression databases
ArrayExpress	Q7JP25.
Bgee	Q7JP25.
Family and domain databases
InterPro	IPR004075. IL1_rcpt_1. IPR000372. LRR-contain_N. IPR000157. TIR_dom. [Graphical view]
Pfam	PF01582. TIR. 1 hit. [Graphical view]
PRINTS	PR01537. INTRLKN1R1F.
SMART	SM00013. LRRNT. 3 hits. SM00255. TIR. 1 hit. [Graphical view]
SUPFAM	SSF52200. TIR. 1 hit.
PROSITE	PS50104. TIR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7JP25_DROME

Accession

Primary (citable) accession number: Q7JP25

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)