aqp-2

Functionⁱ

GO - Molecular functionⁱ

water channel activity
Source: WormBase
Inferred from direct assayⁱ
- 17229810

GO - Biological processⁱ

water transport
Source: WormBase
Inferred from direct assayⁱ
- 17229810

Complete GO annotation...

Keywords - Biological processⁱ

TransportUniRule annotation

Enzyme and pathway databases

Reactomeⁱ	R-CEL-432030. Transport of glycerol from adipocytes to the liver by Aquaporins. R-CEL-432040. Vasopressin regulates renal water homeostasis via Aquaporins. R-CEL-432047. Passive transport by Aquaporins.

Reactomeⁱ

R-CEL-432030. Transport of glycerol from adipocytes to the liver by Aquaporins.
R-CEL-432040. Vasopressin regulates renal water homeostasis via Aquaporins.
R-CEL-432047. Passive transport by Aquaporins.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: AQuaPorin or aquaglyceroporin relatedImported Automatic assertion inferred from database entriesⁱ EMBL:CAA84642.1
Gene namesⁱ	Name:aqp-2Imported Automatic assertion inferred from database entriesⁱ EMBL:CAA84642.1 WormBase:C01G6.1b ORF Names:C01G6.1Imported Automatic assertion inferred from database entriesⁱ WormBase:C01G6.1b , CELE_C01G6.1Imported Automatic assertion inferred from database entriesⁱ EMBL:CAA84642.1
Organismⁱ	Caenorhabditis elegansImported Automatic assertion inferred from database entriesⁱ EMBL:CAA84642.1 Proteomes:UP000001940
Taxonomic identifierⁱ	6239 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
Proteomesⁱ	UP000001940 Componentⁱ: Chromosome II

Organism-specific databases

WormBaseⁱ	C01G6.1b; CE19664; WBGene00000170; aqp-2.

WormBaseⁱ

C01G6.1b; CE19664; WBGene00000170; aqp-2.

Subcellular locationⁱ

Topology

Feature key	Position(s)	Length	Description	Actions
Transmembraneⁱ	20 – 39	20	HelicalSequence analysis Automatic assertion according to rulesⁱ SAM:Phobius	Add BLAST
Transmembraneⁱ	51 – 72	22	HelicalSequence analysis Automatic assertion according to rulesⁱ SAM:Phobius	Add BLAST
Transmembraneⁱ	93 – 118	26	HelicalSequence analysis Automatic assertion according to rulesⁱ SAM:Phobius	Add BLAST
Transmembraneⁱ	152 – 171	20	HelicalSequence analysis Automatic assertion according to rulesⁱ SAM:Phobius	Add BLAST
Transmembraneⁱ	183 – 202	20	HelicalSequence analysis Automatic assertion according to rulesⁱ SAM:Phobius	Add BLAST
Transmembraneⁱ	233 – 254	22	HelicalSequence analysis Automatic assertion according to rulesⁱ SAM:Phobius	Add BLAST

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q7JMQ6.
PRIDEⁱ	Q7JMQ6.

Expressionⁱ

Gene expression databases

Bgeeⁱ	WBGene00000170.
ExpressionAtlasⁱ	Q7JMQ6. baseline and differential.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	6239.C01G6.1a.1.

STRINGⁱ

6239.C01G6.1a.1.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q7JMQ6.
SMRⁱ	Q7JMQ6. Positions 21-258.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the MIP/aquaporin (TC 1.A.8) family. [View classification]UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0224. Eukaryota. COG0580. LUCA.
GeneTreeⁱ	ENSGT00510000046311.
HOGENOMⁱ	HOG000288287.

Family and domain databases

CDDⁱ	cd00333. MIP. 1 hit.
Gene3Dⁱ	1.20.1080.10. 1 hit.
InterProⁱ	IPR023271. Aquaporin-like. IPR000425. MIP. IPR022357. MIP_CS. [Graphical view]
PANTHERⁱ	PTHR19139. PTHR19139. 1 hit.
Pfamⁱ	PF00230. MIP. 1 hit. [Graphical view]
PRINTSⁱ	PR00783. MINTRINSICP.
SUPFAMⁱ	SSF81338. SSF81338. 1 hit.
TIGRFAMsⁱ	TIGR00861. MIP. 1 hit.
PROSITEⁱ	PS00221. MIP. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

Q7JMQ6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MILDKLRAKF HIRKELLRAV LAEFTGTYLL CLIGLSVVAQ KVLPRPEVNE 
        60         70         80         90        100
FIGVNVGFGI AIVFGVAVSA KLSGGHINPA VSFAFLSVGQ ITIVQFIAYF 
       110        120        130        140        150
VAQFFGAFFG AATVYAVYND AINVFDGGVR TVGGPKDTAG IFASYPAPHL 
       160        170        180        190        200
GLVNGFVDQF VATAVFVFLI AHIVDKRNSY PTWLQPILVG TGFVAIGAAF 
       210        220        230        240        250
GYNCGYPVNP ARDFAPRLFT SIFYGGAVFT KWFWVPIVGP FVGAVVGIWL 
       260        270        280 
YYFLIGFHTP QDAEEKYVVL TGNQELKPLT AKESA

Length:285

Mass (Da):30,868

Last modified:July 5, 2004 - v1

Checksum:ⁱ7FC8804D68229049

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284602 Genomic DNA. Translation: CAA84642.1.
RefSeqⁱ	NP_495973.1. NM_063572.3.
UniGeneⁱ	Cel.17495.

Genome annotation databases

EnsemblMetazoaⁱ	C01G6.1b.1; C01G6.1b.1; WBGene00000170. C01G6.1b.2; C01G6.1b.2; WBGene00000170. C01G6.1b.3; C01G6.1b.3; WBGene00000170.
GeneIDⁱ	174467.
UCSCⁱ	C01G6.1a.2. c. elegans.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284602 Genomic DNA. Translation: CAA84642.1.
RefSeqⁱ	NP_495973.1. NM_063572.3.
UniGeneⁱ	Cel.17495.

3D structure databases

ProteinModelPortalⁱ	Q7JMQ6.
SMRⁱ	Q7JMQ6. Positions 21-258.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	6239.C01G6.1a.1.

STRINGⁱ

6239.C01G6.1a.1.

Proteomic databases

PaxDbⁱ	Q7JMQ6.
PRIDEⁱ	Q7JMQ6.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	C01G6.1b.1; C01G6.1b.1; WBGene00000170. C01G6.1b.2; C01G6.1b.2; WBGene00000170. C01G6.1b.3; C01G6.1b.3; WBGene00000170.
GeneIDⁱ	174467.
UCSCⁱ	C01G6.1a.2. c. elegans.

Organism-specific databases

CTDⁱ	174467.
WormBaseⁱ	C01G6.1b; CE19664; WBGene00000170; aqp-2.

Phylogenomic databases

eggNOGⁱ	KOG0224. Eukaryota. COG0580. LUCA.
GeneTreeⁱ	ENSGT00510000046311.
HOGENOMⁱ	HOG000288287.

Enzyme and pathway databases

Reactomeⁱ	R-CEL-432030. Transport of glycerol from adipocytes to the liver by Aquaporins. R-CEL-432040. Vasopressin regulates renal water homeostasis via Aquaporins. R-CEL-432047. Passive transport by Aquaporins.

Reactomeⁱ

R-CEL-432030. Transport of glycerol from adipocytes to the liver by Aquaporins.
R-CEL-432040. Vasopressin regulates renal water homeostasis via Aquaporins.
R-CEL-432047. Passive transport by Aquaporins.

Gene expression databases

Bgeeⁱ	WBGene00000170.
ExpressionAtlasⁱ	Q7JMQ6. baseline and differential.

Family and domain databases

CDDⁱ	cd00333. MIP. 1 hit.
Gene3Dⁱ	1.20.1080.10. 1 hit.
InterProⁱ	IPR023271. Aquaporin-like. IPR000425. MIP. IPR022357. MIP_CS. [Graphical view]
PANTHERⁱ	PTHR19139. PTHR19139. 1 hit.
Pfamⁱ	PF00230. MIP. 1 hit. [Graphical view]
PRINTSⁱ	PR00783. MINTRINSICP.
SUPFAMⁱ	SSF81338. SSF81338. 1 hit.
TIGRFAMsⁱ	TIGR00861. MIP. 1 hit.
PROSITEⁱ	PS00221. MIP. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

Q7JMQ6_CAEEL

Accessionⁱ

Primary (citable) accession number: Q7JMQ6

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	September 7, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q7JMQ6 (Q7JMQ6_CAEEL)

UniProt

Q7JMQ6 - Q7JMQ6_CAEEL

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AQuaPorin or aquaglyceroporin related

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ