Q7G794 (LOX3_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative linoleate 9S-lipoxygenase 3
EC=1.13.11.58

Alternative name(s):
Lipoxygenase 3

Gene names

Ordered Locus Names:	Os03g0700400, LOC_Os03g49350
ORF Names:	OSJNBb0017F17.2

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	866 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure By similarity.
Catalytic activity	Linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
Cofactor	Binds 1 iron ion per subunit. Iron is tightly bound By similarity.
Pathway	Lipid metabolism; oxylipin biosynthesis.
Sequence similarities	Belongs to the lipoxygenase family. Contains 1 lipoxygenase domain. Contains 1 PLAT domain.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis Oxylipin biosynthesis
Ligand	Iron Metal-binding
Molecular function	Dioxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	oxylipin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro lipoxygenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 866	866	Putative linoleate 9S-lipoxygenase 3		PRO_0000220709
Regions
	Domain	33 – 161	129	PLAT
	Domain	164 – 866	703	Lipoxygenase
Sites
	Metal binding	521	1	Iron; catalytic By similarity
	Metal binding	526	1	Iron; catalytic By similarity
	Metal binding	712	1	Iron; catalytic By similarity
	Metal binding	716	1	Iron; catalytic By similarity
	Metal binding	866	1	Iron; via carboxylate; catalytic By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7G794 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: CFABF7A03604367D	FASTA	866	96,251
	10 20 30 40 50 60 MLGGIIDTIT GSSKQSRLKG TVVLMRKNVL DLNDFGATVI DGLGEFLGKG VTCQLISSTA 70 80 90 100 110 120 VDPNNGNRGK VGAEASLEQW LTSSLPSLTT GESRFGVTFD WDVDKLGVPG AIIVKNHHSN 130 140 150 160 170 180 EFFLKTITLD DVPGRAGAVV FLANSWVYPA DKYRYDRVFF ANDAYLPSQM PAALKPYRDD 190 200 210 220 230 240 ELRNLRGDDQ QGPYEEHDRV YRYDVYNDLG SPDSGNPRPI LGGSPDTPYP RRGRTGRKPT 250 260 270 280 290 300 TTDPDSESRL SLVEQIYVPR DERFGHLKMA DFLGYSIKAI AEGIVPAIRT YVDTTPGEFD 310 320 330 340 350 360 SFQDILDLYE GGLKLPDVPA LEELRKRFPL QLVKDLLPAA GDYILKLPMP QIIKQDKEAW 370 380 390 400 410 420 RTDEEFAREV LAGVNPMMIT RLTEFPPKSS LDPSKFGDHT SMITAAHIGS NLEGLTVQQA 430 440 450 460 470 480 LDSNRLYILD HHDRFMPFLI DVNGLEGNFI YATRTLFFLR GDGTLAPLAI ELSEPMIQGD 490 500 510 520 530 540 VTAAKSTVYT PASTGVEAWV WQLAKAYVAV NDSGWHQLIS HWLNTHAVME PFVIATNRQL 550 560 570 580 590 600 SVTHPVHKLL SPHYRDTMTI NALARQTLIN AGGIFEMTVF PGKYALWMSS MVYKNWNFTE 610 620 630 640 650 660 QGLPADLIKR GVAVEDATSP YKVRLLIKDY PYAADGLEIW HAIEQWVGEY LAIYYTDDGV 670 680 690 700 710 720 LRGDAELQAW WAEVREVGHG DLKGAAWWPR MDAVSELRDA CTTIIWIASA LHAAVNFGQY 730 740 750 760 770 780 PYAGYLPNRP TVSRRRMPEP GTEAYGELGR DPERAFIRTI TSQLQTIIGI SLIEVLSKHS 790 800 810 820 830 840 SDEVYLGQRD TPAWTSDARA LEAFRRFSDR LVEIEGKVVG MNGDAGLKNR NGPAEFPYML 850 860 LYPNTSDVTG AAAGITAKGI PNSISI

References

[1]

"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC097368 Genomic DNA. Translation: AAO38441.1. AC093017 Genomic DNA. Translation: AAX95639.1.
RefSeq	NP_001050993.1. NM_001057528.1.
UniGene	Os.16873.
3D structure databases
ProteinModelPortal	Q7G794.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7G794.
Proteomic databases
PRIDE	Q7G794.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4333821.
KEGG	osa:4333821.
Organism-specific databases
Gramene	Q7G794.
Phylogenomic databases
GeneTree	EPGT00070000028239.
PhylomeDB	Q7G794.
ProtClustDB	PLN02337.
Family and domain databases
InterPro	IPR008976. Lipase_LipOase. IPR000907. LipOase. IPR013819. LipOase_C. IPR020834. LipOase_CS. IPR020833. LipOase_Fe_BS. IPR001024. LipOase_LH2. IPR001246. LipOase_pln. [Graphical view]
Gene3D	G3DSA:2.60.60.20. Lipase_LipOase. 1 hit.
KO	K00454.
PANTHER	PTHR11771. LipOase. 1 hit.
Pfam	PF00305. Lipoxygenase. 1 hit. PF01477. PLAT. 1 hit. [Graphical view]
PRINTS	PR00087. LIPOXYGENASE. PR00468. PLTLPOXGNASE.
SMART	SM00308. LH2. 1 hit. [Graphical view]
SUPFAM	SSF49723. Lipase_LipOase. 1 hit. SSF48484. Lipoxygenase. 1 hit.
PROSITE	PS00711. LIPOXYGENASE_1. 1 hit. PS00081. LIPOXYGENASE_2. 1 hit. PS51393. LIPOXYGENASE_3. 1 hit. PS50095. PLAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOX3_ORYSJ

Accession

Primary (citable) accession number: Q7G794

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	May 10, 2005
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program