Q7G6Z2 (EXP12_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Expansin-A12

Alternative name(s):
Alpha-expansin-12
OsEXP12
OsEXPA12
OsaEXPa1.15

Gene names

Name:	EXPA12
Synonyms:	EXP12
Ordered Locus Names:	Os03g0155300, LOC_Os03g06000
ORF Names:	OSJNBa0011L14.18

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	250 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence By similarity.
Subcellular location	Secreted › cell wall By similarity. Membrane; Peripheral membrane protein By similarity.
Tissue specificity	Expressed in roots. Ref.1
Sequence similarities	Belongs to the expansin family. Expansin A subfamily. Contains 1 expansin-like CBD domain. Contains 1 expansin-like EG45 domain.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Cell wall Membrane Secreted
Domain	Signal
Gene Ontology (GO)
Biological process	plant-type cell wall organization Inferred from electronic annotation. Source: InterPro
Cellular component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 24	24	Potential
	Chain	25 – 250	226	Expansin-A12		PRO_0000251991
Regions
	Domain	42 – 156	115	Expansin-like EG45
	Domain	166 – 245	80	Expansin-like CBD

Sequences

	Sequence		Length	Mass (Da)
	Q7G6Z2 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: AEE0729BAF81079B	FASTA	250	26,430
	10 20 30 40 50 60 MARSAFFFHC VAAVAACIAA TAAALSGTAT FYGGSDASGT MGGACGYGNL YSTGYGTNTA 70 80 90 100 110 120 ALSSALFNDG AACGECYQIT CDQSNSKWCK AGTSVTITAT NLCPPDYSKP SNDGGWCNPP 130 140 150 160 170 180 RQHFDMAQPA WEQIGVYRGG IVPVNFQRVS CTRKGGVRFT INGNSYFELV LITNVGGPGS 190 200 210 220 230 240 IKSVQIKGTK TGWVTMSRNW GANWQANNYL NNQAISFSVT STAGKTLVFE DVAPSNWQFG 250 QTFTSGVQFY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Expression of alpha-expansin and expansin-like genes in deepwater rice." Lee Y., Kende H. Plant Physiol. 130:1396-1405(2002) [PubMed: 12428004] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], TISSUE SPECIFICITY.
[2]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Nomenclature for members of the expansin superfamily of genes and proteins." Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J., Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C., Voesenek L.A.C. Plant Mol. Biol. 55:311-314(2004) [PubMed: 15604683] [Abstract] Cited for: NOMENCLATURE.

Web resources

EXPANSIN homepage

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY046929 mRNA. Translation: AAL04422.1. AF394548 Genomic DNA. Translation: AAL24484.1. AC105730 Genomic DNA. Translation: AAM51844.1. DP000009 Genomic DNA. Translation: ABF94051.1.
RefSeq	NP_001049005.1. NM_001055540.1.
UniGene	Os.20535.
3D structure databases
HSSP	HSSP built from PDB template 1WC2 based on UniProtKB P82186.
ProteinModelPortal	Q7G6Z2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g06000.1; LOC_Os03g06000.1; LOC_Os03g06000.
GeneID	4331665.
KEGG	osa:4331665.
Organism-specific databases
Gramene	Q7G6Z2.
Phylogenomic databases
GeneTree	EPGT00070000027988.
OMA	DIAPANW.
PhylomeDB	Q7G6Z2.
ProtClustDB	CLSN2693538.
Family and domain databases
InterPro	IPR014733. Barwin-like_endoglucanase. IPR009009. Barwin-related_endoglucanase. IPR007118. Expan_Lol_pI. IPR007117. Expan_Lol_pI_C. IPR002963. Expansin. IPR007112. Expansin/allergen_DPBB_dom. [Graphical view]
Gene3D	G3DSA:2.40.40.10. Barwin. 1 hit. G3DSA:2.60.40.760. Expan_Lol_pI_C. 1 hit.
Pfam	PF03330. DPBB_1. 1 hit. PF01357. Pollen_allerg_1. 1 hit. [Graphical view]
PRINTS	PR01226. EXPANSIN. PR01225. EXPANSNFAMLY.
SMART	SM00837. DPBB_1. 1 hit. [Graphical view]
SUPFAM	SSF50685. Barwin_like. 1 hit. SSF49590. Expan_Lol_pI_C. 1 hit.
PROSITE	PS50843. EXPANSIN_CBD. 1 hit. PS50842. EXPANSIN_EG45. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EXP12_ORYSJ

Accession

Primary (citable) accession number: Q7G6Z2
Secondary accession number(s): Q946I9

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2006
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program