Q7F1X5 (4CLL5_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-coumarate--CoA ligase-like 5
EC=6.2.1.-

Gene names

Name:	4CLL5
Ordered Locus Names:	Os01g0901500, LOC_Os01g67530
ORF Names:	B1065G12.9

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	542 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Domain	Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family.
Sequence caution	The sequence BAF07025.2 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 542	542	4-coumarate--CoA ligase-like 5		PRO_0000351631
Regions
	Nucleotide binding	204 – 212	9	ATP By similarity
	Nucleotide binding	354 – 359	6	ATP By similarity
	Region	284 – 353	70	SBD1
	Region	354 – 397	44	SBD2
	Compositional bias	6 – 12	7	Poly-Pro
Sites
	Binding site	418	1	ATP By similarity
	Binding site	433	1	ATP By similarity
	Binding site	524	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7F1X5 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 4DFFFFDC7440E4B0	FASTA	542	57,347
	10 20 30 40 50 60 MADRAPPPPP PPAGIDSRSG FCAATRIFHS TRAPGDLPPE SLPMTAAAYA FSLLSSSTLP 70 80 90 100 110 120 GRPALVDAAT GIAISYPSFL AAVRSLAGGL WCSLGLRPGD VALVVAPSRL EVPVLDFALM 130 140 150 160 170 180 SIGAVVSPAN PVSTPEEYAH QVALSRPVVA FAAPEVAAKL PEHVRCVVIG SDEYGRLAAS 190 200 210 220 230 240 DGRRAAAPAA VAVKQSDTAA VLYSSGTTGR VKAVAITHRN LIALMSLHAD NREKVAREAA 250 260 270 280 290 300 EAGEEPPPPA VTLLPIPLFH VFGFMMVLRS VSMGETSVLM ERFDFIAALR AIERYRVTLL 310 320 330 340 350 360 PAAPPVLVAM VKYEEARRRD LSSLLVIGIG GAPLGREVAE QFASVFPNVE LVQGYGLTES 370 380 390 400 410 420 SGAVAATVGP EESKAYGSVG KLGSHLQAKI VDPSTGYVGD DEATAATVDS EGWLKTGDLC 430 440 450 460 470 480 YFNEDGFLYI VDRLKELIKY KGYQVPPAEL EHILQSHPGI ADAAVIPYPD EEAGELPMAF 490 500 510 520 530 540 IVRQPGSNIT KEQVMDYVAK QVAPYKKVRR VAFVTAIPKS PAGKILRREL VQQALSMGAS KL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed: 18089549] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[4]	"Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella." de Azevedo Souza C., Barbazuk B., Ralph S.G., Bohlmann J., Hamberger B., Douglas C.J. New Phytol. 179:987-1003(2008) [PubMed: 18627494] [Abstract] Cited for: GENE FAMILY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003791 Genomic DNA. Translation: BAB90527.1. AP008207 Genomic DNA. Translation: BAF07025.2. Sequence problems.
RefSeq	NP_001045111.2. NM_001051646.2.
UniGene	Os.5174.
3D structure databases
HSSP	HSSP built from PDB template 1LCI based on UniProtKB P08659.
ProteinModelPortal	Q7F1X5.
ModBase	Search...
Proteomic databases
PRIDE	Q7F1X5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4325044.
KEGG	osa:4325044.
NMPDR	fig|39947.1.peg.7271.
Organism-specific databases
Gramene	Q7F1X5.
Phylogenomic databases
HOGENOM	HBG604116.
PhylomeDB	Q7F1X5.
ProtClustDB	CLSN2692180.
Family and domain databases
InterPro	IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

4CLL5_ORYSJ

Accession

Primary (citable) accession number: Q7F1X5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 14, 2008
Last sequence update:	February 15, 2005
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program