Q7DK11 (Q7DK11_AGGAC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cytolethal distending toxin EMBL BAA35118.1

Submitted name:
Cytolethal distending toxin protein C EMBL AAC70899.1

Gene names

Name:	cdtC EMBL BAA35118.1
ORF Names:	D7S_2350 EMBL EFE02830.1

Organism

Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans) EMBL BAA35118.1

Taxonomic identifier

714 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Aggregatibacter

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2F2F
Gene Ontology (GO)
Biological process	pathogenesis Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7DK11 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 87D6C68267D129F5	FASTA	186	20,708
	10 20 30 40 50 60 MKKYLLSFLL SMILTLTSHA ESNPDPTTYP DVELSPPPRI SLRSLLTAQP IKNDHYDSHN 70 80 90 100 110 120 YLSTHWELID YKGKEYEKLR DGGTLVQFKV VGAAKCFAFP GEGTTDCKDI DHTVFNLIPT 130 140 150 160 170 180 NTGAFLIKDA LLGFCMTSHD FDDLRLEPCG ISVSGRTFSL AYQWGILPPF GPSKILRPPV GRNQGS

References

[1]	"Identification of a cytolethal distending toxin gene locus and features of a virulence-associated region in Actinobacillus actinomycetemcomitans." Mayer M.P., Bueno L.C., Hansen E.J., DiRienzo J.M. Infect. Immun. 67:1227-1237(1999) [PubMed: 10024565] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Y4 EMBL AAC70899.1.
[2]	"Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans." Yamada T., Komoto J., Saiki K., Konishi K., Takusagawa F. Protein Sci. 15:362-372(2006) [PubMed: 16434747] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS).
[3]	"Genome sequence of naturally competent Aggregatibacter actinomycetemcomitans serotype a strain D7S-1." Chen C., Kittichotirat W., Chen W., Downey J.S., Si Y., Bumgarner R. J. Bacteriol. 192:2643-2644(2010) [PubMed: 20348265] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: D7S-1 EMBL EFE02830.1.
[4]	"Cytolethal distending toxin." Saiki K., Konishi K., Yoshikawa M. Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: ATCC29522 EMBL BAA35118.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF006830 Genomic DNA. Translation: AAC70899.1.
AB017807 Genomic DNA. Translation: BAA35118.1.
ADCF01000001 Genomic DNA. Translation: EFE02830.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2F2F	X-ray	2.40	C/F	1-186	[»]

ProteinModelPortal

Q7DK11.

SMR

Q7DK11. Positions 25-178.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

PATRIC

36267088. VBIAggAct151347_2063.

Family and domain databases

InterPro

IPR003558. CDtoxinA/C.
IPR008997. Ricin_B-rel_lectin.
[Graphical view]

Pfam

PF03498. CDtoxinA. 1 hit.
[Graphical view]

SUPFAM

SSF50370. RicinB_like. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q7DK11_AGGAC

Accession

Primary (citable) accession number: Q7DK11
Secondary accession number(s): D4EB08

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)