ID   Q7CWV1_AGRFC            Unreviewed;       442 AA.
AC   Q7CWV1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 88.
DE   SubName: Full=Protelomerase {ECO:0000313|EMBL:AAK88254.1};
GN   Name=telA {ECO:0000313|EMBL:AAK88254.1};
GN   OrderedLocusNames=Atu2523 {ECO:0000313|EMBL:AAK88254.1};
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK88254.1, ECO:0000313|Proteomes:UP000000813};
RN   [1] {ECO:0000313|EMBL:AAK88254.1, ECO:0000313|Proteomes:UP000000813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [2] {ECO:0000313|EMBL:AAK88254.1, ECO:0000313|Proteomes:UP000000813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
RN   [3] {ECO:0007829|PDB:4F41, ECO:0007829|PDB:4F43}
RP   X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 102-421.
RX   PubMed=22582388; DOI=10.1074/jbc.M112.369488;
RA   Huang W.M., DaGloria J., Fox H., Ruan Q., Tillou J., Shi K., Aihara H.,
RA   Aron J., Casjens S.;
RT   "Linear chromosome-generating system of Agrobacterium tumefaciens C58:
RT   protelomerase generates and protects hairpin ends.";
RL   J. Biol. Chem. 287:25551-25563(2012).
RN   [4] {ECO:0007829|PDB:4DWP, ECO:0007829|PDB:4E0G}
RP   X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 103-421.
RX   PubMed=23382649; DOI=10.1371/journal.pbio.1001472;
RA   Shi K., Huang W.M., Aihara H.;
RT   "An enzyme-catalyzed multistep DNA refolding mechanism in hairpin telomere
RT   formation.";
RL   PLoS Biol. 11:e1001472-e1001472(2013).
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DR   EMBL; AE007869; AAK88254.1; -; Genomic_DNA.
DR   RefSeq; NP_355469.1; NC_003062.2.
DR   RefSeq; WP_006312144.1; NC_003062.2.
DR   PDB; 4DWP; X-ray; 2.35 A; A=103-421.
DR   PDB; 4E0G; X-ray; 2.20 A; A=103-421.
DR   PDB; 4E0J; X-ray; 2.30 A; A=103-421.
DR   PDB; 4E0P; X-ray; 2.20 A; A=103-421.
DR   PDB; 4E0Y; X-ray; 2.40 A; A=103-420.
DR   PDB; 4E0Z; X-ray; 2.42 A; A=103-421.
DR   PDB; 4E10; X-ray; 2.51 A; A=103-420.
DR   PDB; 4F41; X-ray; 2.50 A; A=102-421.
DR   PDB; 4F43; X-ray; 2.35 A; A=102-421.
DR   PDBsum; 4DWP; -.
DR   PDBsum; 4E0G; -.
DR   PDBsum; 4E0J; -.
DR   PDBsum; 4E0P; -.
DR   PDBsum; 4E0Y; -.
DR   PDBsum; 4E0Z; -.
DR   PDBsum; 4E10; -.
DR   PDBsum; 4F41; -.
DR   PDBsum; 4F43; -.
DR   AlphaFoldDB; Q7CWV1; -.
DR   SMR; Q7CWV1; -.
DR   DIP; DIP-60106N; -.
DR   STRING; 176299.Atu2523; -.
DR   EnsemblBacteria; AAK88254; AAK88254; Atu2523.
DR   KEGG; atu:Atu2523; -.
DR   PATRIC; fig|176299.10.peg.2534; -.
DR   eggNOG; ENOG502ZR09; Bacteria.
DR   HOGENOM; CLU_619163_0_0_5; -.
DR   OrthoDB; 8324304at2; -.
DR   Proteomes; UP000000813; Chromosome circular.
DR   Gene3D; 6.10.140.1780; -; 2.
DR   Gene3D; 1.10.443.30; Telomere resolvase; 1.
DR   InterPro; IPR038280; ResT_cat_sf.
DR   InterPro; IPR032047; Telomere_res.
DR   Pfam; PF16684; Telomere_res; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4DWP, ECO:0007829|PDB:4E0G};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000813}.
SQ   SEQUENCE   442 AA;  50321 MW;  5C717813FB9FDE0B CRC64;
     MLAAKRKTKT PVLVERIDQF VGQIKEAMKS DDASRNRKIR DLWDAEVRYH FDNGRTEKTL
     ELYIMKYRNA LKAEFGPKST PLAICNMKKL RERLNTYIAR GDYPKTGVAT SIVEKIERAE
     FNTAGRKPTV LLRIADFIAA MNGMDAKQDM QALWDAEIAI MNGRAQTTII SYITKYRNAI
     REAFGDDHPM LKIATGDAAM YDEARRVKME KIANKHGALI TFENYRQVLK ICEDCLKSSD
     PLMIGIGLIG MTGRRPYEVF TQAEFSPAPY GKGVSKWSIL FNGQAKTKQG EGTKFGITYE
     IPVLTRSETV LAAYKRLRES GQGKLWHGMS IDDFSSETRL LLRDTVFNLF EDVWPKEELP
     KPYGLRHLYA EVAYHNFAPP HVTKNSYFAA ILGHNNNDLE TSLSYMTYTL PEDRDNALAR
     LKRTNERTLQ QMATIAPVSR KG
//