Q7CPC3 (Q7CPC3_SALTY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sensory kinase in two-component regulatory system with CpxR EMBL AAL22898.1
EC=2.7.3.- EMBL AAL22898.1

Gene names

Name:	cpxA EMBL AAL22898.1
Ordered Locus Names:	STM4058

Organism

Salmonella typhimurium

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	457 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. SAAS SAAS003660
Subcellular location	Membrane; Multi-pass membrane protein By similarity RuleBase RU003568.
Sequence similarities	Contains 1 histidine kinase domain. SAAS SAAS009082

Ontologies

Keywords
Biological process	Two-component regulatory system SAAS SAAS005467
Cellular component	Membrane
Domain	Transmembrane SAAS SAAS005467 RuleBase RU003568
Ligand	ATP-binding SAAS SAAS005467 Nucleotide-binding
Molecular function	Kinase SAAS SAAS004358 RuleBase RU003568 EMBL AAL22898.1 Transferase
PTM	Phosphoprotein SAAS SAAS005467 RuleBase RU003568
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	peptidyl-histidine phosphorylation Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW two-component sensor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7CPC3 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 5F7C8EEA944488FC	FASTA	457	51,610
	10 20 30 40 50 60 MIGSLTARIF AIFWLTLALV LMLVLMLPKL DSRQMTELLD SEQRQGLMIE QHVEAELAND 70 80 90 100 110 120 PPNDLMWWRR LFRAIDKWAP PGQRLLLVTS EGRVIGAERS EMQIIRNFIG QADNADHPQK 130 140 150 160 170 180 KKYGRVEMVG PFSVRDGEDN YQLYLIRPAS SSQSDFINLL FDRPLLLLIV TMLVSSPLLL 190 200 210 220 230 240 WLAWSLAKPA RKLKNAADEV AQGNLRQHPE LEAGPQEFLA AGASFNQMVT ALERMMTSQQ 250 260 270 280 290 300 RLLSDISHEL RTPLTRLQLG TALLRRRGGE SKELERIETE AQRLDSMIND LLVMSRNQQK 310 320 330 340 350 360 NALVSETMKA NQLWGEVLDN AAFEAEQMGK SLTVNYPPGP WPLYGNPNAL ESALENIVRN 370 380 390 400 410 420 ALRYSHTKIE VGFSVDKDGI TITVDDDGPG VSPEDREQIF RPFYRTDEAR DRESGGTGLG 430 440 450 LAIVESAMQQ HRGWVKADDS PLGGLRLTLW LPLYKRT

References

[1]

"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE006468 Genomic DNA. Translation: AAL22898.1.
RefSeq	NP_462939.1. NC_003197.1.
3D structure databases
ProteinModelPortal	Q7CPC3.
ModBase	Search...
Proteomic databases
PRIDE	Q7CPC3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1255585.
GenomeReviews	Gene locus STM4058 in contig AE006468_GR.
KEGG	stm:STM4058.
PATRIC	32386996. VBISalEnt20916_4278.
Phylogenomic databases
HOGENOM	HBG334875.
OMA	NDILDNA.
ProtClustDB	PRK09470.
Enzyme and pathway databases
BioCyc	STYP99287:STM4058-MONOMER.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR003660. HAMP_linker_domain. IPR004358. Sig_transdc_His_kin-like_C. IPR003661. Sig_transdc_His_kin_sub1_dim/P. IPR005467. Sig_transdc_His_kinase_core. IPR009082. Sig_transdc_His_kinase_dimeric. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
KO	K07640.
Pfam	PF00672. HAMP. 1 hit. PF02518. HATPase_c. 1 hit. PF00512. HisKA. 1 hit. [Graphical view]
PRINTS	PR00344. BCTRLSENSOR.
SMART	SM00304. HAMP. 1 hit. SM00387. HATPase_c. 1 hit. SM00388. HisKA. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF47384. His_kin_homodim. 1 hit.
PROSITE	PS50885. HAMP. 1 hit. PS50109. HIS_KIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7CPC3_SALTY

Accession

Primary (citable) accession number: Q7CPC3

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)