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Q7CPC3

- Q7CPC3_SALTY

UniProt

Q7CPC3 - Q7CPC3_SALTY

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Protein
Submitted name: Sensory kinase in two-component regulatory system with CpxR
Gene
cpxA, STM4058
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationsImported, Transferase

    Keywords - Biological processi

    Two-component regulatory systemSAAS annotations

    Keywords - Ligandi

    ATP-bindingSAAS annotations, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-4088-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sensory kinase in two-component regulatory system with CpxRImported (EC:2.7.3.-Imported)
    Gene namesi
    Name:cpxAImported
    Ordered Locus Names:STM4058Imported
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Imported
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    Complete GO annotation...

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Keywords - PTMi

    PhosphoproteinUniRule annotationSAAS annotations

    Proteomic databases

    PRIDEiQ7CPC3.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM4058.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7CPC3.

    Family & Domainsi

    Sequence similaritiesi

    Contains histidine kinase domain.SAAS annotations

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotations

    Phylogenomic databases

    HOGENOMiHOG000269851.
    KOiK07640.
    OMAiEHIFRPF.
    OrthoDBiEOG6G4VQG.
    PhylomeDBiQ7CPC3.

    Family and domain databases

    Gene3Di1.10.287.130. 1 hit.
    3.30.565.10. 1 hit.
    InterProiIPR003661. EnvZ-like_dim/P.
    IPR003660. HAMP_linker_domain.
    IPR003594. HATPase_ATP-bd.
    IPR004358. Sig_transdc_His_kin-like_C.
    IPR005467. Sig_transdc_His_kinase_core.
    IPR009082. Sig_transdc_His_kinase_dimeric.
    [Graphical view]
    PfamiPF00672. HAMP. 1 hit.
    PF02518. HATPase_c. 1 hit.
    PF00512. HisKA. 1 hit.
    [Graphical view]
    PRINTSiPR00344. BCTRLSENSOR.
    SMARTiSM00304. HAMP. 1 hit.
    SM00387. HATPase_c. 1 hit.
    SM00388. HisKA. 1 hit.
    [Graphical view]
    SUPFAMiSSF47384. SSF47384. 1 hit.
    SSF55874. SSF55874. 1 hit.
    PROSITEiPS50885. HAMP. 1 hit.
    PS50109. HIS_KIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7CPC3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIGSLTARIF AIFWLTLALV LMLVLMLPKL DSRQMTELLD SEQRQGLMIE    50
    QHVEAELAND PPNDLMWWRR LFRAIDKWAP PGQRLLLVTS EGRVIGAERS 100
    EMQIIRNFIG QADNADHPQK KKYGRVEMVG PFSVRDGEDN YQLYLIRPAS 150
    SSQSDFINLL FDRPLLLLIV TMLVSSPLLL WLAWSLAKPA RKLKNAADEV 200
    AQGNLRQHPE LEAGPQEFLA AGASFNQMVT ALERMMTSQQ RLLSDISHEL 250
    RTPLTRLQLG TALLRRRGGE SKELERIETE AQRLDSMIND LLVMSRNQQK 300
    NALVSETMKA NQLWGEVLDN AAFEAEQMGK SLTVNYPPGP WPLYGNPNAL 350
    ESALENIVRN ALRYSHTKIE VGFSVDKDGI TITVDDDGPG VSPEDREQIF 400
    RPFYRTDEAR DRESGGTGLG LAIVESAMQQ HRGWVKADDS PLGGLRLTLW 450
    LPLYKRT 457
    Length:457
    Mass (Da):51,610
    Last modified:July 5, 2004 - v1
    Checksum:i5F7C8EEA944488FC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL22898.1.
    RefSeqiNP_462939.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL22898; AAL22898; STM4058.
    GeneIDi1255585.
    KEGGistm:STM4058.
    PATRICi32386996. VBISalEnt20916_4278.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL22898.1 .
    RefSeqi NP_462939.1. NC_003197.1.

    3D structure databases

    ProteinModelPortali Q7CPC3.
    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 99287.STM4058.

    Proteomic databases

    PRIDEi Q7CPC3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL22898 ; AAL22898 ; STM4058 .
    GeneIDi 1255585.
    KEGGi stm:STM4058.
    PATRICi 32386996. VBISalEnt20916_4278.

    Phylogenomic databases

    HOGENOMi HOG000269851.
    KOi K07640.
    OMAi EHIFRPF.
    OrthoDBi EOG6G4VQG.
    PhylomeDBi Q7CPC3.

    Enzyme and pathway databases

    BioCyci SENT99287:GCTI-4088-MONOMER.

    Family and domain databases

    Gene3Di 1.10.287.130. 1 hit.
    3.30.565.10. 1 hit.
    InterProi IPR003661. EnvZ-like_dim/P.
    IPR003660. HAMP_linker_domain.
    IPR003594. HATPase_ATP-bd.
    IPR004358. Sig_transdc_His_kin-like_C.
    IPR005467. Sig_transdc_His_kinase_core.
    IPR009082. Sig_transdc_His_kinase_dimeric.
    [Graphical view ]
    Pfami PF00672. HAMP. 1 hit.
    PF02518. HATPase_c. 1 hit.
    PF00512. HisKA. 1 hit.
    [Graphical view ]
    PRINTSi PR00344. BCTRLSENSOR.
    SMARTi SM00304. HAMP. 1 hit.
    SM00387. HATPase_c. 1 hit.
    SM00388. HisKA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47384. SSF47384. 1 hit.
    SSF55874. SSF55874. 1 hit.
    PROSITEi PS50885. HAMP. 1 hit.
    PS50109. HIS_KIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.

    Entry informationi

    Entry nameiQ7CPC3_SALTY
    AccessioniPrimary (citable) accession number: Q7CPC3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 5, 2004
    Last sequence update: July 5, 2004
    Last modified: July 9, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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