UniProtKB - Q7CL43 (Q7CL43_YERPE)
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Protein
Deoxyribose-phosphate aldolase
Gene
YPO3622
Organism
Yersinia pestis
Status
Functioni
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.SAAS annotation
Catalytic activityi
2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.SAAS annotation
: 2-deoxy-D-ribose 1-phosphate degradation Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.SAAS annotationProteins known to be involved in the 2 steps of the subpathway in this organism are:
- no protein annotated in this organism
- Deoxyribose-phosphate aldolase (YPO3622), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase 1 (deoC1), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC3), Deoxyribose-phosphate aldolase 2 (deoC2)
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.
GO - Molecular functioni
- deoxyribose-phosphate aldolase activity Source: GO_Central
GO - Biological processi
- carbohydrate catabolic process Source: GO_Central
- deoxyribonucleotide catabolic process Source: GO_Central
- deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | LyaseSAAS annotationImported |
Ligand | Schiff baseSAAS annotation |
Enzyme and pathway databases
UniPathwayi | UPA00002; UER00468. |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:YPO3622Imported |
Organismi | Yersinia pestisImported |
Taxonomic identifieri | 632 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Yersinia › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm SAAS annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmSAAS annotationFamily & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4108PMK. Bacteria. COG0274. LUCA. |
HOGENOMi | HOG000241645. |
KOi | K01619. |
OMAi | CAAFYSA. |
Family and domain databases
CDDi | cd00959. DeoC. 1 hit. |
Gene3Di | 3.20.20.70. 1 hit. |
InterProi | View protein in InterPro IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/FbaB/lacD_aldolase. IPR028581. DeoC_typeI. |
PANTHERi | PTHR10889. PTHR10889. 1 hit. PTHR10889:SF1. PTHR10889:SF1. 1 hit. |
Pfami | View protein in Pfam PF01791. DeoC. 1 hit. |
PIRSFi | PIRSF001357. DeoC. 1 hit. |
SMARTi | View protein in SMART SM01133. DeoC. 1 hit. |
TIGRFAMsi | TIGR00126. deoC. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q7CL43-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIDFNDPRQV AKAIQFTNVN ADLTREGVIK HLNICLEYQF DAAMIAPCWV
60 70 80 90 100
YLAKDVLKGS GVRVATTVNF PQANDTTAMK VAIVRELAKE GADEFDFPPN
110 120 130 140 150
PGFLLGGLDE LYFNELKEVT HIAHDLGMKV KAMLEFGFIT EEAMKIKATR
160 170 180 190 200
YAYEAGIDWV KQSSGWGKGG CAATVEDVQL LKANIQAPCR VKVSGKVNTL
210 220 230
EKMKEMFLAG AELVGTSSGP ELVKGLTGDI NAY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL590842 Genomic DNA. Translation: CAL22210.1. |
PIRi | AG0440. |
RefSeqi | WP_002210030.1. NZ_PDBR01000050.1. YP_002348507.1. NC_003143.1. |
Genome annotation databases
EnsemblBacteriai | AAM83841; AAM83841; y0247. AAS64069; AAS64069; YP_3925. |
GeneIDi | 1176442. |
KEGGi | ype:YPO3622. |
PATRICi | fig|214092.21.peg.4122. |
Similar proteinsi
Entry informationi
Entry namei | Q7CL43_YERPE | |
Accessioni | Q7CL43Primary (citable) accession number: Q7CL43 Secondary accession number(s): Q74PI2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | March 28, 2018 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |