YPO3622

Functionⁱ

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.SAAS annotation

Catalytic activityⁱ

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.SAAS annotation

Pathwayⁱ: 2-deoxy-D-ribose 1-phosphate degradation

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.SAAS annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:

no protein annotated in this organism
Deoxyribose-phosphate aldolase (YPO3622), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase 1 (deoC1), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase (deoC3), Deoxyribose-phosphate aldolase 2 (deoC2)

This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.

GO - Molecular functionⁱ

deoxyribose-phosphate aldolase activity Source: GO_Central

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate catabolic process Source: GO_Central
deoxyribonucleotide catabolic process Source: GO_Central
deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	LyaseSAAS annotationImported
Ligand	Schiff baseSAAS annotation

Enzyme and pathway databases

UniPathwayⁱ	UPA00002; UER00468.

UniPathwayⁱ

UPA00002; UER00468.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Deoxyribose-phosphate aldolaseSAAS annotation (EC:4.1.2.4SAAS annotation)
Gene namesⁱ	Ordered Locus Names:YPO3622Imported
Organismⁱ	Yersinia pestisImported
Taxonomic identifierⁱ	632 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Yersinia › Yersinia pseudotuberculosis complex
Proteomesⁱ	UP000000815 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00535486

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

CytoplasmSAAS annotation

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q7CL43.

PaxDbⁱ

Q7CL43.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	187410.y0247.

STRINGⁱ

187410.y0247.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.SAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG4108PMK. Bacteria. COG0274. LUCA.
HOGENOMⁱ	HOG000241645.
KEGG Orthology (KO) More...KOⁱ	K01619.
OMAⁱ	CAAFYSA.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00959. DeoC. 1 hit.
Gene3Dⁱ	3.20.20.70. 1 hit.
InterProⁱ	View protein in InterPro IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/FbaB/lacD_aldolase. IPR028581. DeoC_typeI.
PANTHERⁱ	PTHR10889. PTHR10889. 1 hit. PTHR10889:SF1. PTHR10889:SF1. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01791. DeoC. 1 hit.
PIRSFⁱ	PIRSF001357. DeoC. 1 hit.
SMARTⁱ	View protein in SMART SM01133. DeoC. 1 hit.
TIGRFAMsⁱ	TIGR00126. deoC. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q7CL43-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MIDFNDPRQV AKAIQFTNVN ADLTREGVIK HLNICLEYQF DAAMIAPCWV 
        60         70         80         90        100
YLAKDVLKGS GVRVATTVNF PQANDTTAMK VAIVRELAKE GADEFDFPPN 
       110        120        130        140        150
PGFLLGGLDE LYFNELKEVT HIAHDLGMKV KAMLEFGFIT EEAMKIKATR 
       160        170        180        190        200
YAYEAGIDWV KQSSGWGKGG CAATVEDVQL LKANIQAPCR VKVSGKVNTL 
       210        220        230 
EKMKEMFLAG AELVGTSSGP ELVKGLTGDI NAY

Length:233

Mass (Da):25,470

Last modified:July 5, 2004 - v1

Checksum:ⁱ9E3D42F7539138B7

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL590842 Genomic DNA. Translation: CAL22210.1.
PIRⁱ	AG0440.
NCBI Reference Sequences More...RefSeqⁱ	WP_002210030.1. NZ_PDBR01000050.1. YP_002348507.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAM83841; AAM83841; y0247. AAS64069; AAS64069; YP_3925.
GeneIDⁱ	1176442.
KEGGⁱ	ype:YPO3622.
PATRICⁱ	fig\|214092.21.peg.4122.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q7CL43	A0A0H2W9P2 A0A0E1NT29 A0A0M1V9J8 A0A0H2YN28 A0A208S454	Yersinia pestis Yersinia pestis bv. Antiqua (strain Antiqua) Yersinia pestis biovar Orientalis str. IP275 Yersinia pestis bv. Antiqua (strain Nepal516) Yersinia pestis subsp. microtus	233	UniRef100_A0A0H2W9P2	Cluster: Deoxyribose-phosphate aldolase	6

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q7CL43	A0A0H2W9P2 A0A0E1NT29 A0A0M1V9J8 A0A0H2YN28 A0A208S454 A0A2A7VMQ0 A0A0H3B003 A0A0U1QUA2 A0A0U1EUX0 Q665B1 +11	Yersinia pestis Yersinia pestis bv. Antiqua (strain Antiqua) Yersinia pestis biovar Orientalis str. IP275 Yersinia pestis bv. Antiqua (strain Nepal516) Yersinia pestis subsp. microtus Yersinia pseudotuberculosis Yersinia pseudotuberculosis serotype O:3 (strain YPIII) Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) Yersinia intermedia Yersinia pseudotuberculosis serotype I (strain IP32953) And more	233	UniRef90_A0A0H2W9P2	Cluster: Deoxyribose-phosphate aldolase	22

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q7CL43	A0A0H2W9P2 A0A0E1NT29 A0A0M1V9J8 A0A0H2YN28 A0A208S454 A0A2A7VMQ0 A0A0H3B003 A0A0U1QUA2 A0A0U1EUX0 Q665B1 +15	Yersinia pestis Yersinia pestis bv. Antiqua (strain Antiqua) Yersinia pestis biovar Orientalis str. IP275 Yersinia pestis bv. Antiqua (strain Nepal516) Yersinia pestis subsp. microtus Yersinia pseudotuberculosis Yersinia pseudotuberculosis serotype O:3 (strain YPIII) Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) Yersinia intermedia Yersinia pseudotuberculosis serotype I (strain IP32953) And more	233	UniRef50_A0A0H2W9P2	Cluster: Deoxyribose-phosphate aldolase	26

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL590842 Genomic DNA. Translation: CAL22210.1.
PIRⁱ	AG0440.
NCBI Reference Sequences More...RefSeqⁱ	WP_002210030.1. NZ_PDBR01000050.1. YP_002348507.1. NC_003143.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	187410.y0247.

STRINGⁱ

187410.y0247.

Proteomic databases

PaxDbⁱ	Q7CL43.

PaxDbⁱ

Q7CL43.

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	1145194.
Structural Biology Knowledgebase	Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAM83841; AAM83841; y0247. AAS64069; AAS64069; YP_3925.
GeneIDⁱ	1176442.
KEGGⁱ	ype:YPO3622.
PATRICⁱ	fig\|214092.21.peg.4122.

Phylogenomic databases

eggNOGⁱ	ENOG4108PMK. Bacteria. COG0274. LUCA.
HOGENOMⁱ	HOG000241645.
KEGG Orthology (KO) More...KOⁱ	K01619.
OMAⁱ	CAAFYSA.

Enzyme and pathway databases

UniPathwayⁱ	UPA00002; UER00468.

UniPathwayⁱ

UPA00002; UER00468.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00959. DeoC. 1 hit.
Gene3Dⁱ	3.20.20.70. 1 hit.
InterProⁱ	View protein in InterPro IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/FbaB/lacD_aldolase. IPR028581. DeoC_typeI.
PANTHERⁱ	PTHR10889. PTHR10889. 1 hit. PTHR10889:SF1. PTHR10889:SF1. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01791. DeoC. 1 hit.
PIRSFⁱ	PIRSF001357. DeoC. 1 hit.
SMARTⁱ	View protein in SMART SM01133. DeoC. 1 hit.
TIGRFAMsⁱ	TIGR00126. deoC. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q7CL43_YERPE
Accessionⁱ	Q7CL43Primary (citable) accession number: Q7CL43 Secondary accession number(s): Q74PI2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	March 28, 2018
	This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q7CL43 (Q7CL43_YERPE)

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Deoxyribose-phosphate aldolase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 2-deoxy-D-ribose 1-phosphate degradation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

Pathwayⁱ: 2-deoxy-D-ribose 1-phosphate degradation

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ