YPO3622

Functionⁱ

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.SAAS annotation

Catalytic activityⁱ

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.SAAS annotation

Pathwayⁱ: 2-deoxy-D-ribose 1-phosphate degradation

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.SAAS annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:

no protein annotated in this organism
Deoxyribose-phosphate aldolase (YPO3622), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase 1 (deoC1), Deoxyribose-phosphate aldolase (deoC3), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase 2 (deoC2)

This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.

GO - Molecular functionⁱ

deoxyribose-phosphate aldolase activity Source: GO_Central

Complete GO annotation...

GO - Biological processⁱ

carbohydrate catabolic process Source: GO_Central
deoxyribonucleotide catabolic process Source: GO_Central

Complete GO annotation...

Keywordsⁱ

Molecular function	LyaseSAAS annotationImported
Ligand	Schiff baseSAAS annotation

Enzyme and pathway databases

UniPathwayⁱ	UPA00002; UER00468.

UniPathwayⁱ

UPA00002; UER00468.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Deoxyribose-phosphate aldolaseSAAS annotation (EC:4.1.2.4SAAS annotation)
Gene namesⁱ	Ordered Locus Names:YPO3622Imported
Organismⁱ	Yersinia pestisImported
Taxonomic identifierⁱ	632 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Yersinia › Yersinia pseudotuberculosis complex
Proteomesⁱ	UP000000815 Componentⁱ: Chromosome

Subcellular locationⁱ

Cytoplasm
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00535486

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

CytoplasmSAAS annotation

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	187410.y0247.

STRINGⁱ

187410.y0247.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.SAAS annotation

Phylogenomic databases

eggNOGⁱ	ENOG4108PMK. Bacteria. COG0274. LUCA.
HOGENOMⁱ	HOG000241645.
KEGG Orthology (KO) More...KOⁱ	K01619.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00959. DeoC. 1 hit.
Gene3Dⁱ	3.20.20.70. 1 hit.
InterProⁱ	View protein in InterPro IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/FbaB/lacD_aldolase. IPR028581. DeoC_typeI.
PANTHERⁱ	PTHR10889. PTHR10889. 1 hit. PTHR10889:SF9. PTHR10889:SF9. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01791. DeoC. 1 hit.
PIRSFⁱ	PIRSF001357. DeoC. 1 hit.
SMARTⁱ	View protein in SMART SM01133. DeoC. 1 hit.
TIGRFAMsⁱ	TIGR00126. deoC. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q7CL43-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MIDFNDPRQV AKAIQFTNVN ADLTREGVIK HLNICLEYQF DAAMIAPCWV 
        60         70         80         90        100
YLAKDVLKGS GVRVATTVNF PQANDTTAMK VAIVRELAKE GADEFDFPPN 
       110        120        130        140        150
PGFLLGGLDE LYFNELKEVT HIAHDLGMKV KAMLEFGFIT EEAMKIKATR 
       160        170        180        190        200
YAYEAGIDWV KQSSGWGKGG CAATVEDVQL LKANIQAPCR VKVSGKVNTL 
       210        220        230 
EKMKEMFLAG AELVGTSSGP ELVKGLTGDI NAY

Length:233

Mass (Da):25,470

Last modified:July 5, 2004 - v1

Checksum:ⁱ9E3D42F7539138B7

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL590842 Genomic DNA. Translation: CAL22210.1.
PIRⁱ	AG0440.
NCBI Reference Sequences More...RefSeqⁱ	WP_002210030.1. NZ_LT605018.1. YP_002348507.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaⁱ	AAM83841; AAM83841; y0247. AAS64069; AAS64069; YP_3925.
GeneIDⁱ	1176442.
KEGGⁱ	ype:YPO3622. ypj:CH55_2579. ypk:y0247. ypl:CH46_1417. ypm:YP_3925. ypv:BZ15_4066. ypw:CH59_2377.
PATRICⁱ	fig\|214092.21.peg.4122.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL590842 Genomic DNA. Translation: CAL22210.1.
PIRⁱ	AG0440.
NCBI Reference Sequences More...RefSeqⁱ	WP_002210030.1. NZ_LT605018.1. YP_002348507.1. NC_003143.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	187410.y0247.

STRINGⁱ

187410.y0247.

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	1145194.
Structural Biology Knowledgebase	Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAM83841; AAM83841; y0247. AAS64069; AAS64069; YP_3925.
GeneIDⁱ	1176442.
KEGGⁱ	ype:YPO3622. ypj:CH55_2579. ypk:y0247. ypl:CH46_1417. ypm:YP_3925. ypv:BZ15_4066. ypw:CH59_2377.
PATRICⁱ	fig\|214092.21.peg.4122.

Phylogenomic databases

eggNOGⁱ	ENOG4108PMK. Bacteria. COG0274. LUCA.
HOGENOMⁱ	HOG000241645.
KEGG Orthology (KO) More...KOⁱ	K01619.

Enzyme and pathway databases

UniPathwayⁱ	UPA00002; UER00468.

UniPathwayⁱ

UPA00002; UER00468.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00959. DeoC. 1 hit.
Gene3Dⁱ	3.20.20.70. 1 hit.
InterProⁱ	View protein in InterPro IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/FbaB/lacD_aldolase. IPR028581. DeoC_typeI.
PANTHERⁱ	PTHR10889. PTHR10889. 1 hit. PTHR10889:SF9. PTHR10889:SF9. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01791. DeoC. 1 hit.
PIRSFⁱ	PIRSF001357. DeoC. 1 hit.
SMARTⁱ	View protein in SMART SM01133. DeoC. 1 hit.
TIGRFAMsⁱ	TIGR00126. deoC. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q7CL43_YERPE
Accessionⁱ	Q7CL43Primary (citable) accession number: Q7CL43 Secondary accession number(s): Q74PI2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 5, 2004
	Last sequence update:	July 5, 2004
	Last modified:	July 5, 2017
	This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q7CL43 (Q7CL43_YERPE)

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Deoxyribose-phosphate aldolase

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Functionⁱ

Catalytic activityⁱ

Pathwayⁱ: 2-deoxy-D-ribose 1-phosphate degradation

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q7CL43 (Q7CL43_YERPE)

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Deoxyribose-phosphate aldolase

YPO3622

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">‘Function’</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: 2-deoxy-D-ribose 1-phosphate degradation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

Pathwayⁱ: 2-deoxy-D-ribose 1-phosphate degradation

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ