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UniProtKB - Q7CL43 (Q7CL43_YERPE)

UniProt

Q7CL43 - Q7CL43_YERPE

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Protein

Deoxyribose-phosphate aldolase

Gene

deoC3

Organism
Yersinia pestis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.SAAS annotation

Catalytic activityi

2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.SAAS annotation

Pathwayi: 2-deoxy-D-ribose 1-phosphate degradation

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.SAAS annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Deoxyribose-phosphate aldolase (deoC3), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase 1 (deoC1), Deoxyribose-phosphate aldolase (deoC), Deoxyribose-phosphate aldolase 2 (deoC2)
This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LyaseSAAS annotationImported

Keywords - Ligandi

Schiff baseSAAS annotation

Enzyme and pathway databases

BioCyciYPES214092:GKDD-3579-MONOMER.
UniPathwayiUPA00002; UER00468.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxyribose-phosphate aldolaseSAAS annotation (EC:4.1.2.4SAAS annotation)
Gene namesi
Name:deoC3Imported
Ordered Locus Names:y0247Imported, YP_3925Imported, YPO3622Imported
OrganismiYersinia pestisImported
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia ›
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi187410.y0247.

Family & Domainsi

Sequence similaritiesi

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.SAAS annotation

Phylogenomic databases

eggNOGiENOG4108PMK. Bacteria.
COG0274. LUCA.
HOGENOMiHOG000241645.
KOiK01619.
OMAiPCWVPLA.

Family and domain databases

CDDicd00959. DeoC. 1 hit.
Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
[Graphical view]
PANTHERiPTHR10889. PTHR10889. 1 hit.
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF001357. DeoC. 1 hit.
SMARTiSM01133. DeoC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00126. deoC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7CL43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDFNDPRQV AKAIQFTNVN ADLTREGVIK HLNICLEYQF DAAMIAPCWV 
        60         70         80         90        100
YLAKDVLKGS GVRVATTVNF PQANDTTAMK VAIVRELAKE GADEFDFPPN 
       110        120        130        140        150
PGFLLGGLDE LYFNELKEVT HIAHDLGMKV KAMLEFGFIT EEAMKIKATR 
       160        170        180        190        200
YAYEAGIDWV KQSSGWGKGG CAATVEDVQL LKANIQAPCR VKVSGKVNTL 
       210        220        230 
EKMKEMFLAG AELVGTSSGP ELVKGLTGDI NAY
Length:233
Mass (Da):25,470
Last modified:July 5, 2004 - v1
Checksum:i9E3D42F7539138B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009952 Genomic DNA. Translation: AAM83841.1.
AE017042 Genomic DNA. Translation: AAS64069.1.
AL590842 Genomic DNA. Translation: CAL22210.1.
PIRiAG0440.
RefSeqiWP_002210030.1. NZ_LQAY01000047.1.
YP_002348507.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM83841; AAM83841; y0247.
AAS64069; AAS64069; YP_3925.
KNX90556; KNX90556; ACX54_3143.
KNX91641; KNX91641; ACX52_3564.
GeneIDi1176442.
KEGGiype:YPO3622.
ypj:CH55_2579.
ypk:y0247.
ypl:CH46_1417.
ypm:YP_3925.
ypv:BZ15_4066.
ypw:CH59_2377.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009952 Genomic DNA. Translation: AAM83841.1.
AE017042 Genomic DNA. Translation: AAS64069.1.
AL590842 Genomic DNA. Translation: CAL22210.1.
PIRiAG0440.
RefSeqiWP_002210030.1. NZ_LQAY01000047.1.
YP_002348507.1. NC_003143.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi187410.y0247.

Protocols and materials databases

DNASUi1145194.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM83841; AAM83841; y0247.
AAS64069; AAS64069; YP_3925.
KNX90556; KNX90556; ACX54_3143.
KNX91641; KNX91641; ACX52_3564.
GeneIDi1176442.
KEGGiype:YPO3622.
ypj:CH55_2579.
ypk:y0247.
ypl:CH46_1417.
ypm:YP_3925.
ypv:BZ15_4066.
ypw:CH59_2377.

Phylogenomic databases

eggNOGiENOG4108PMK. Bacteria.
COG0274. LUCA.
HOGENOMiHOG000241645.
KOiK01619.
OMAiPCWVPLA.

Enzyme and pathway databases

UniPathwayiUPA00002; UER00468.
BioCyciYPES214092:GKDD-3579-MONOMER.

Family and domain databases

CDDicd00959. DeoC. 1 hit.
Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR011343. DeoC.
IPR002915. DeoC/FbaB/lacD_aldolase.
[Graphical view]
PANTHERiPTHR10889. PTHR10889. 1 hit.
PfamiPF01791. DeoC. 1 hit.
[Graphical view]
PIRSFiPIRSF001357. DeoC. 1 hit.
SMARTiSM01133. DeoC. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00126. deoC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ7CL43_YERPE
AccessioniPrimary (citable) accession number: Q7CL43
Secondary accession number(s): Q74PI2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 7, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.