Q7CK81 (Q7CK81_YERPE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative thioredoxin-like protein EMBL AAM84501.1

Submitted name:
Thioredoxin 2 EMBL AAS60928.1

Gene names

Name:	trxC EMBL AAM84501.1
Ordered Locus Names:	y0919 EMBL AAM84501.1, YP_0661 EMBL AAS60928.1, YPO3270 EMBL CAL21863.1

Organism

Yersinia pestis [Reference proteome] [HAMAP]

Taxonomic identifier

632 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	145 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 thioredoxin domain. RuleBase RU004207

Ontologies

Keywords
Ligand	Metal-binding PDB 3P2A Zinc PDB 3P2A
Technical term	3D-structure PDB 3P2A Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: InterPro glycerol ether metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	electron carrier activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein disulfide oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	5	1	Zinc PDB 3P2A
	Metal binding	8	1	Zinc PDB 3P2A
	Metal binding	25	1	Zinc PDB 3P2A
	Metal binding	28	1	Zinc PDB 3P2A

Sequences

	Sequence		Length	Mass (Da)
	Q7CK81 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 70C082F613AB87F0	FASTA	145	16,168
	10 20 30 40 50 60 MNTVCTACMA TNRLPEERID DGAKCGRCGH SLFDGEVINA TAETLDKLLQ DDLPMVIDFW 70 80 90 100 110 120 APWCGPCRSF APIFAETAAE RAGKVRFVKV NTEAEPALST RFRIRSIPTI MLYRNGKMID 130 140 MLNGAVPKAP FDNWLDEQLS RDPNS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Yersinia pestis, the causative agent of plague." Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:523-527(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CO-92 / Biovar Orientalis and CO92 EMBL CAL21863.1.
[2]	"Genome sequence of Yersinia pestis KIM." Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. , Matson J.S., Blattner F.R., Perry R.D. J. Bacteriol. 184:4601-4611(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KIM EMBL AAM84501.1 and KIM10+ / Biovar Mediaevalis.
[3]	"Annotation and evolutionary relationships of a small regulatory RNA gene micF and its target ompF in Yersinia species." Delihas N. BMC Microbiol. 3:13-13(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: CO92 EMBL CAL21863.1.
[4]	"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans." Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R. DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 91001 EMBL AAS60928.1 and 91001 / Biovar Mediaevalis.
[5]	"Genetics of metabolic variations between Yersinia pestis biovars and the proposal of a new biovar, microtus." Zhou D., Tong Z., Song Y., Han Y., Pei D., Pang X., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R., Du Z., Wang J., Guo Z., Wang J., Huang P., Yang R. J. Bacteriol. 186:5147-5152(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 91001 EMBL AAS60928.1.
[6]	"Crystal Structure of Thioredoxin 2 from Yersinia pestis." Center for Structural Genomics of Infectious Diseases (CSGID) Kim Y., Zhou M., Grimshaw S., Anderson W.F., Joachimiak A. Submitted (OCT-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) IN COMPLEX WITH ZINC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE009952 Genomic DNA. Translation: AAM84501.1.
AE017042 Genomic DNA. Translation: AAS60928.1.
AL590842 Genomic DNA. Translation: CAL21863.1.

PIR

AD0397.

RefSeq

NP_668250.1. NC_004088.1.
NP_992051.1. NC_005810.1.
YP_002348170.1. NC_003143.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3P2A	X-ray	2.20	A/B/C/D	1-145	[»]

ModBase

Search...

Protein-protein interaction databases

STRING

214092.YPO3270.

Protocols and materials databases

DNASU

1145866.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAM84501; AAM84501; y0919.
AAS60928; AAS60928; YP_0661.

GeneID

1145866.
1176083.
2765797.

KEGG

ype:YPO3270.
ypk:y0919.
ypm:YP_0661.

Phylogenomic databases

HOGENOM

HOG000292979.

KO

K03672.

OMA

IVCPHCH.

ProtClustDB

PRK10996.

Family and domain databases

Gene3D

3.40.30.10. 1 hit.

InterPro

IPR005746. Thioredoxin.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]

PANTHER

PTHR10438. PTHR10438. 1 hit.

Pfam

PF00085. Thioredoxin. 1 hit.
[Graphical view]

PRINTS

PR00421. THIOREDOXIN.

SUPFAM

SSF52833. Thiordxn-like_fd. 1 hit.

TIGRFAMs

TIGR01068. thioredoxin. 1 hit.

PROSITE

PS00194. THIOREDOXIN_1. 1 hit.
PS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q7CK81.

Entry information

Entry name

Q7CK81_YERPE

Accession

Primary (citable) accession number: Q7CK81
Secondary accession number(s): Q74X06

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)