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Q7CJ96

- PTA_YERPE

UniProt

Q7CJ96 - PTA_YERPE

Protein

Phosphate acetyltransferase

Gene

pta

Organism
Yersinia pestis
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Involved in acetate metabolism.By similarity

    Catalytic activityi

    Acetyl-CoA + phosphate = CoA + acetyl phosphate.

    Pathwayi

    GO - Molecular functioni

    1. phosphate acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. acetyl-CoA biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Enzyme and pathway databases

    BioCyciYPES214092:GKDD-2535-MONOMER.
    UniPathwayiUPA00340; UER00459.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphate acetyltransferase (EC:2.3.1.8)
    Alternative name(s):
    Phosphotransacetylase
    Gene namesi
    Name:pta
    Ordered Locus Names:YPO2567, y1620, YP_2378
    OrganismiYersinia pestis
    Taxonomic identifieri632 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
    ProteomesiUP000000815: Chromosome, UP000001019: Chromosome, UP000002490: Chromosome

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 717717Phosphate acetyltransferasePRO_0000405555Add
    BLAST

    Proteomic databases

    PRIDEiQ7CJ96.

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Protein-protein interaction databases

    IntActiQ7CJ96. 2 interactions.
    STRINGi214092.YPO2567.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7CJ96.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni390 – 717328Phosphate acetyltransferaseAdd
    BLAST

    Domaini

    The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.By similarity

    Sequence similaritiesi

    In the N-terminal section; belongs to the CobB/CobQ family.Curated
    In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

    Phylogenomic databases

    eggNOGiCOG0280.
    HOGENOMiHOG000053797.
    KOiK13788.
    OMAiKPIAQPH.
    OrthoDBiEOG6BKJ5W.

    Family and domain databases

    Gene3Di3.40.1390.20. 1 hit.
    3.40.50.300. 1 hit.
    InterProiIPR010766. DRTGG.
    IPR016475. P-Actrans_bac.
    IPR027417. P-loop_NTPase.
    IPR004614. P_AcTrfase.
    IPR002505. PTA_PTB.
    IPR028979. Ser_kin/Pase_Hpr_N_like.
    [Graphical view]
    PfamiPF07085. DRTGG. 1 hit.
    PF01515. PTA_PTB. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    SSF75138. SSF75138. 1 hit.
    TIGRFAMsiTIGR00651. pta. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7CJ96-1 [UniParc]FASTAAdd to Basket

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    MSRTIMLIPT GTSVGLTSVS LGVIRSMEQK GVSLSVFKPI AQPRAGNDAP    50
    DQTTTIIRAN SSITAAEPLN MNYVETLLSS NQQDVLMEEI VARYHENTKD 100
    AEVVLVEGLV PTRKHQFANA LNYEIAKTLN AEIVFVIALG NDSPDQLKER 150
    IELARSSFGG SKNKNITGVI INKLNAPVDE QGRTRPDLSE IFDDSTKASV 200
    ANIDPSQLFA NSPIPVLGCV PWSFELIATR AIDMAKHLNA RIINEGDIKT 250
    RRVKSVTFCA RSIPHMLEHF RPGSLLVTSA DRPDVLVSAC LAAMNGVEIG 300
    AILLTGGYAI DDRINNLCER AFQTGLPVFM VDTNTWQTSL SLQSFNLEVP 350
    ADDHERVEKL QNYVASHISS EWIDSLTAAS ERPRRLSPPA FRYELTELAR 400
    KAGKRIVLPE GDEPRTIKAA SICAERGIAT CVLLGNPEEI QRVATSQGVE 450
    LGKGVEIIDP VAVREQYVPR LVELRKSKGM TEVVAREQLE DNVVLGTLML 500
    EKGEVDGLVS GAVHTTANTI RPPLQLIKTA PGSSLVSSVF FMLLPDQVLV 550
    YGDCAINPDP TAEQLSEIAI QSADSAAAFG IEPRVAMISY STGNSGAGSD 600
    VEKVREATRL AQEKRPDLII DGPLQYDAAI MADVAKSKAP NSPVAGRATV 650
    FIFPDLNTGN TTYKAVQRSA DLISIGPMLQ GMRKPVNDLS RGALVDDIVY 700
    TVALTAIQSA QADSAAS 717
    Length:717
    Mass (Da):77,402
    Last modified:July 5, 2004 - v1
    Checksum:i4AB841751C30C2A3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009952 Genomic DNA. Translation: AAM85189.1.
    AE017042 Genomic DNA. Translation: AAS62583.1.
    AL590842 Genomic DNA. Translation: CAL21192.1.
    PIRiAE0313.
    RefSeqiNP_668938.1. NC_004088.1.
    NP_993706.1. NC_005810.1.
    YP_002347528.1. NC_003143.1.

    Genome annotation databases

    EnsemblBacteriaiAAM85189; AAM85189; y1620.
    AAS62583; AAS62583; YP_2378.
    GeneIDi1146567.
    1175398.
    2766685.
    KEGGiype:YPO2567.
    ypk:y1620.
    ypm:YP_2378.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009952 Genomic DNA. Translation: AAM85189.1 .
    AE017042 Genomic DNA. Translation: AAS62583.1 .
    AL590842 Genomic DNA. Translation: CAL21192.1 .
    PIRi AE0313.
    RefSeqi NP_668938.1. NC_004088.1.
    NP_993706.1. NC_005810.1.
    YP_002347528.1. NC_003143.1.

    3D structure databases

    ProteinModelPortali Q7CJ96.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q7CJ96. 2 interactions.
    STRINGi 214092.YPO2567.

    Proteomic databases

    PRIDEi Q7CJ96.

    Protocols and materials databases

    DNASUi 1146567.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAM85189 ; AAM85189 ; y1620 .
    AAS62583 ; AAS62583 ; YP_2378 .
    GeneIDi 1146567.
    1175398.
    2766685.
    KEGGi ype:YPO2567.
    ypk:y1620.
    ypm:YP_2378.

    Phylogenomic databases

    eggNOGi COG0280.
    HOGENOMi HOG000053797.
    KOi K13788.
    OMAi KPIAQPH.
    OrthoDBi EOG6BKJ5W.

    Enzyme and pathway databases

    UniPathwayi UPA00340 ; UER00459 .
    BioCyci YPES214092:GKDD-2535-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1390.20. 1 hit.
    3.40.50.300. 1 hit.
    InterProi IPR010766. DRTGG.
    IPR016475. P-Actrans_bac.
    IPR027417. P-loop_NTPase.
    IPR004614. P_AcTrfase.
    IPR002505. PTA_PTB.
    IPR028979. Ser_kin/Pase_Hpr_N_like.
    [Graphical view ]
    Pfami PF07085. DRTGG. 1 hit.
    PF01515. PTA_PTB. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006107. PhpActrans_proteobac. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    SSF75138. SSF75138. 1 hit.
    TIGRFAMsi TIGR00651. pta. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KIM10+ / Biovar Mediaevalis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CO-92 / Biovar Orientalis.
    3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
      Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
      , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
      DNA Res. 11:179-197(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 91001 / Biovar Mediaevalis.

    Entry informationi

    Entry nameiPTA_YERPE
    AccessioniPrimary (citable) accession number: Q7CJ96
    Secondary accession number(s): Q74T19
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 8, 2011
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3