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Q7C3R3 (XYLA_ENTFA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Xylose isomerase
EC=5.3.1.5
Gene names
Name:xylA
Ordered Locus Names:EF_0556
ORF Names:ef-0082
OrganismEnterococcus faecalis (Streptococcus faecalis)
Taxonomic identifier1351 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Enterococcaceae › Enterococcus

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_00455

Subunit structure

Homotetramer By similarity. HAMAP MF_00455

Subcellular location

Cytoplasm By similarity HAMAP MF_00455.

Sequence similarities

Belongs to the xylose isomerase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylose isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 435435Xylose isomerase HAMAP MF_00455
PRO_0000195777

Sites

Active site991 By similarity
Active site1021 By similarity
Metal binding2301Magnesium 1 By similarity
Metal binding2661Magnesium 1 By similarity
Metal binding2661Magnesium 2 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2941Magnesium 1 By similarity
Metal binding3051Magnesium 2 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3371Magnesium 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7C3R3 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 01550D06F506B96E

FASTA43549,735
        10         20         30         40         50         60 
MVYFPKIEKI KYEGTNTKNM YAFRHYNSEE IIMGKTMKEH LRFAVAYWHT MTQDGSDPFG 

        70         80         90        100        110        120 
KAVNKRSWLG ESPMETAKKR VIAFFEILEK LDVEYFCFHD IDIAPEGNSL KEFFSNIDEI 

       130        140        150        160        170        180 
TDLIKEKMDE TGIKLLWNTA NMFSNPRYVN GAASTNNANV YAIAAAQVKK GLDVSKKLGG 

       190        200        210        220        230        240 
ENYVFWGGRE GYETLLNTDM KFEQDNIARL FKMAIFYGEK IGHKPQFLIE PKPKEPSKHQ 

       250        260        270        280        290        300 
YDFDAATTMA FILKYGLEKD FKLNLEANHA TLAGHTFEHE LNVARNYGAL GSIDANQGDV 

       310        320        330        340        350        360 
LLGWDTDEFP TNVYDVTLAM YEILENGGIE PGGINFDSKV RRSSFEMEDL LLAHIAGMDT 

       370        380        390        400        410        420 
FARGLKSAMK LKEDRFFEDL KEQRYSSFKK GIGAKIISGK ENLESLTNYA LKNDEPIIES 

       430 
SHIEYVKNIL NDYLY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF454824 Genomic DNA. Translation: AAM75286.1.
AE016830 Genomic DNA. Translation: AAO80397.1.
RefSeqNP_814326.1. NC_004668.1.

3D structure databases

ProteinModelPortalQ7C3R3.
SMRQ7C3R3. Positions 3-434.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1199466.
GenomeReviewsGene locus EF_0556 in contig AE016830_GR.
KEGGefa:EF0556.
NMPDRfig|226185.1.peg.512.
PATRIC21851524. VBIEntFae7065_0513.
TIGREF_0556.

Phylogenomic databases

HOGENOMHBG297199.
OMALLGWDTD.
ProtClustDBPRK05474.

Enzyme and pathway databases

BioCycEFAE226185:EF_0556-MONOMER.

Family and domain databases

HAMAPMF_00455. Xylose_isom_A.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01805.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR02630. Xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXYLA_ENTFA
AccessionPrimary (citable) accession number: Q7C3R3
Secondary accession number(s): Q8KU78
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: July 5, 2004
Last modified: January 25, 2012
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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