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Protein

Adenine deaminase

Gene

ade

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:SF3796, S3972
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001424361 – 588Adenine deaminaseAdd BLAST588

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ7BZ90
SMRiQ7BZ90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN Bacteria
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiHEIANVM

Family and domain databases

CDDicd01295 AdeC, 1 hit
Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR01178 ade, 1 hit

Sequencei

Sequence statusi: Complete.

Q7BZ90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNSINHKFH HISRAEYQEL LAVSRGDAVA DYIIDNVSIL DLINAGEISG
60 70 80 90 100
PIVIKGRYIA GVGAEYADTP ALQRIDARGA TAVPGFIDAH LHIESSMMTP
110 120 130 140 150
VTFETATLPR GLTTVICDPH EIVNVMGEAG FAWFARCAEQ ARQNQYLQVS
160 170 180 190 200
SCVPALEGCD VNGASFTLEQ MLAWRDHPQV TGLAEMMDYP GVINGQNALL
210 220 230 240 250
DKLDAFRYLT LDGHCPGLGG KELNAYIAAG IENCHESYQL EEGRRKLQLG
260 270 280 290 300
MSLMIREGSA ASNLNALAPL INEFNSPQCM LCTDDRNPWE IAHEGHIDAL
310 320 330 340 350
IRRLIEQHNV PLHVAYRVAS WSTARHFGLN HLGLLAPGKQ ADIVLLSDAR
360 370 380 390 400
KVTVQQVLVK GEPIDAQTLQ AEESARLALS APPYGNTIAR QPVSASDFAL
410 420 430 440 450
QFTPGKRYRV IDVIHNELIT HSRSSVYSEN GFDRDDVCFI AVLERYGQRL
460 470 480 490 500
APACGLLGGF GLNEGALAAT VSHDSHNIVV IGRSAEEMAL AVNQVIQDGG
510 520 530 540 550
GLCVVRNGQV QSHLPLPIAG LMSTDTAQSL AEQIDALKAA ARECGPLPDE
560 570 580
PFIQMAFLSL PVIPALKLTS QGLFDGEKFA FTTLEVTE
Length:588
Mass (Da):63,727
Last modified:July 5, 2004 - v1
Checksum:iFF162B7FA286A7AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN45236.1
AE014073 Genomic DNA Translation: AAP18960.1
RefSeqiNP_709529.1, NC_004337.2
WP_001065670.1, NZ_MTPK01000023.1

Genome annotation databases

EnsemblBacteriaiAAN45236; AAN45236; SF3796
AAP18960; AAP18960; S3972
GeneIDi1026080
KEGGisfl:SF3796
sfx:S3972
PATRICifig|198214.7.peg.4481

Similar proteinsi

Entry informationi

Entry nameiADEC_SHIFL
AccessioniPrimary (citable) accession number: Q7BZ90
Secondary accession number(s): Q83MJ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: July 5, 2004
Last modified: April 25, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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