ID   Q7BTX0_YERPE            Unreviewed;       141 AA.
AC   Q7BTX0; A0A0H2W1K9; A0A2U2GUQ5; A0A384L6P2; A0A3G5L133; A0A5P8YM68;
AC   A0A9Y2Y783; Q74YV6; Q7ARG9;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 113.
DE   SubName: Full=YopH targeting protein {ECO:0000313|EMBL:ADV16709.1, ECO:0000313|EMBL:CAB54972.1};
DE   SubName: Full=YopH chaperone {ECO:0000313|EMBL:AAC62591.1, ECO:0000313|EMBL:AAC69820.1};
GN   Name=sycH {ECO:0000313|EMBL:AAC62591.1};
GN   Synonyms=Y0082 {ECO:0000313|EMBL:AAC69820.1};
GN   OrderedLocusNames=YPCD1.95c {ECO:0000313|EMBL:CAB54972.1};
OS   Yersinia pestis.
OG   Plasmid pCD1 {ECO:0000313|EMBL:AAC62591.1,
OG   ECO:0000313|Proteomes:UP000000815}, and
OG   Plasmid pCD1-pMT1 {ECO:0000313|EMBL:ADV16709.1}.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632 {ECO:0000313|EMBL:ADV16709.1};
RN   [1] {ECO:0000313|EMBL:AAC69820.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=KIM5 {ECO:0000313|EMBL:AAC69820.1};
RC   PLASMID=pCD1 {ECO:0000313|EMBL:AAC69820.1};
RX   PubMed=9746557;
RA   Perry R.D., Straley S.C., Fetherston J.D., Rose D.J., Gregor J.,
RA   Blattner F.R.;
RT   "DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of
RT   Yersinia pestis KIM5.";
RL   Infect. Immun. 66:4611-4623(1998).
RN   [2] {ECO:0000313|EMBL:AAC62591.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=KIM5 {ECO:0000313|EMBL:AAC62591.1};
RC   PLASMID=pCD1 {ECO:0000313|EMBL:AAC62591.1};
RX   PubMed=9748454;
RA   Hu P., Elliott J., McCready P., Skowronski E., Garnes J., Kobayashi A.,
RA   Brubaker R.R., Garcia E.;
RT   "Structural organization of virulence-associated plasmids of Yersinia
RT   pestis.";
RL   J. Bacteriol. 180:5192-5202(1998).
RN   [3] {ECO:0000313|EMBL:CAB54972.1, ECO:0000313|Proteomes:UP000000815}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 {ECO:0000313|EMBL:CAB54972.1}, and CO-92 / Biovar
RC   Orientalis {ECO:0000313|Proteomes:UP000000815};
RC   PLASMID=Plasmid pCD1 {ECO:0000313|Proteomes:UP000000815};
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Leather S., Karlyshev A.V., Moule S.,
RA   Oyston P.C.F., Quail M., Rutherford K., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [4] {ECO:0007829|PDB:1TTW}
RP   X-RAY CRYSTALLOGRAPHY (2.38 ANGSTROMS) OF 1-138.
RX   PubMed=15333930; DOI=10.1107/s0907444904017597;
RA   Phan J., Tropea J.E., Waugh D.S.;
RT   "Structure of the Yersinia pestis type III secretion chaperone SycH in
RT   complex with a stable fragment of YscM2.";
RL   Acta Crystallogr. D 60:1591-1599(2004).
RN   [5] {ECO:0000313|EMBL:ADV16709.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=C790 {ECO:0000313|EMBL:ADV16709.1};
RC   PLASMID=pCD1-pMT1 {ECO:0000313|EMBL:ADV16709.1};
RX   PubMed=21197443;
RA   Rajanna C., Revazishvili T., Rashid M.H., Chubinidze S., Bakanidze L.,
RA   Tsanava S., Imnadze P., Bishop-Lilly K.A., Sozhamannan S., Gibbons H.S.,
RA   Morris J.G., Sulakvelidze A.;
RT   "Characterization of pPCP1 plasmids in Yersinia pestis strains isolated
RT   from the former Soviet Union.";
RL   Int. J. Microbiol. 2010:760819-760819(2010).
RN   [6] {ECO:0007829|PDB:4GF3}
RP   X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).
RX   PubMed=23519663; DOI=10.1107/s0907444912051086;
RA   Vujanac M., Stebbins C.E.;
RT   "Context-dependent protein folding of a virulence peptide in the bacterial
RT   and host environments: structure of an SycH-YopH chaperone-effector
RT   complex.";
RL   Acta Crystallogr. D 69:546-554(2013).
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DR   EMBL; AF053946; AAC62591.1; -; Genomic_DNA.
DR   EMBL; AF074612; AAC69820.1; -; Genomic_DNA.
DR   EMBL; HQ612242; ADV16709.1; -; Genomic_DNA.
DR   EMBL; AL117189; CAB54972.1; -; Genomic_DNA.
DR   RefSeq; NP_395224.1; NC_003131.1.
DR   RefSeq; NP_857766.1; NC_004836.1.
DR   RefSeq; NP_857969.1; NC_004839.1.
DR   RefSeq; WP_002213267.1; NZ_WUCM01000133.1.
DR   PDB; 1TTW; X-ray; 2.38 A; A=1-138.
DR   PDB; 4GF3; X-ray; 1.90 A; A=1-141.
DR   PDBsum; 1TTW; -.
DR   PDBsum; 4GF3; -.
DR   PaxDb; 214092-5832510; -.
DR   DNASU; 1149334; -.
DR   GeneID; 66841068; -.
DR   KEGG; ype:YPCD1.95c; -.
DR   KEGG; ypj:CH55_4330; -.
DR   KEGG; ypl:CH46_4401; -.
DR   KEGG; ypm:YP_pCD87; -.
DR   KEGG; ypv:BZ15_4356; -.
DR   KEGG; ypw:CH59_4444; -.
DR   PATRIC; fig|214092.21.peg.103; -.
DR   eggNOG; ENOG5030F4Y; Bacteria.
DR   HOGENOM; CLU_1824599_0_0_6; -.
DR   OMA; VFMRAGI; -.
DR   OrthoDB; 7065547at2; -.
DR   Proteomes; UP000000815; Plasmid pCD1.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR   CDD; cd17030; T3SC_IA_SycH-like; 1.
DR   Gene3D; 3.30.1460.10; -; 1.
DR   InterPro; IPR010261; Tir_chaperone.
DR   Pfam; PF05932; CesT; 1.
DR   SUPFAM; SSF69635; Type III secretory system chaperone-like; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:1TTW, ECO:0007829|PDB:4GF3};
KW   Plasmid {ECO:0000313|EMBL:ADV16709.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000815}.
SQ   SEQUENCE   141 AA;  15763 MW;  D623C09AB0A72F44 CRC64;
     MRTYSSLLEE FATELGLEEI ETNELGHGAV TIDKIWVVHL APINEKELVA FMRAGILTGQ
     SQLYDILRKN LFSPLSGVIR CALDKDDHWL LWSQLNINDT SGTQLASVLT SLVDKAVTLS
     CEPTMKKEED DHRPSSSHLL V
//