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Q7AJA5 (PKN1_CHLPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase pkn1
EC=2.7.11.1
Gene names
Name:pkn1
Ordered Locus Names:CPn_0148, CP_0625, CPj0148, CpB0149
OrganismChlamydia pneumoniae (Chlamydophila pneumoniae) [Complete proteome] [HAMAP]
Taxonomic identifier83558 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length619 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth By similarity.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 619619Serine/threonine-protein kinase pkn1
PRO_0000171188

Regions

Domain15 – 302288Protein kinase
Nucleotide binding21 – 299ATP By similarity

Sites

Active site1411Proton acceptor By similarity

Experimental info

Sequence conflict3091V → A in AAF38440. Ref.2
Sequence conflict5151I → V in AAP98082. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q7AJA5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: CA312E28304D7D80

FASTA61970,355
        10         20         30         40         50         60 
MESEKDIGAK FLGDYRILYR KGQSLWSEDL LAEHRFIKKR YLIRLLLPDL GSSQPFMEAF 

        70         80         90        100        110        120 
HDVVVKLAKL NHPGILSIEN VSESEGRCFL VTQEQDIPIL SLTQYLKSIP RKLTELEIVD 

       130        140        150        160        170        180 
IVSQLASLLD YVHSEGLAQE EWNLDSVYIH ILNGVPKVIL PDLGFASLIK ERILDGFISD 

       190        200        210        220        230        240 
EENRESKIKE RVLLHTSEGK QGREDTYAFG AITYYLLFGF LPQGIFPMPS KVFSDFIYDW 

       250        260        270        280        290        300 
DFLISSCLSC FMEERAKELF PLIRKKTLGE ELQNVVTNCI ESSLREVPDP LESSQNLPQA 

       310        320        330        340        350        360 
VLKVGETKVS HQQKESAEHL EFVLVEACSI DEAMDTAIES ESSSGVEEEG YSLALQSLLV 

       370        380        390        400        410        420 
REPVVSRYVE AEKEEPKPQP ILTEMVLIEG GEFSRGSVEG QRDELPVHKV ILHSFFLDVH 

       430        440        450        460        470        480 
PVTNEQFIRY LECCGSEQDK YYNELIRLRD SRIQRRSGRL VIEPGYAKHP VVGVTWYGAS 

       490        500        510        520        530        540 
GYAEWIGKRL PTEAEWEIAA SGGVAALRYP CGEEIEKSRA NFFTADTTTV MSYPPNPYGL 

       550        560        570        580        590        600 
YDMAGNVYEW CQDWYGYDFY EISAQEPESP QGPAQGVYRV LRGGCWKSLK DDLRCAHRHR 

       610 
NNPGAVNSTY GFRCAKNIN

« Hide

References

[1]"Comparative genomes of Chlamydia pneumoniae and C. trachomatis."
Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W., Olinger L., Grimwood J., Davis R.W., Stephens R.S.
Nat. Genet. 21:385-389(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CWL029.
[2]"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39."
Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. expand/collapse author list , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M.
Nucleic Acids Res. 28:1397-1406(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AR39.
[3]"Comparison of whole genome sequences of Chlamydia pneumoniae J138 from Japan and CWL029 from USA."
Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K., Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.
Nucleic Acids Res. 28:2311-2314(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: J138.
[4]"The genome sequence of Chlamydia pneumoniae TW183 and comparison with other Chlamydia strains based on whole genome sequence analysis."
Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P., Schneider S., Pohl T., Essig A., Marre R., Melchers K.
Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: TW-183.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE001363 Genomic DNA. Translation: AAD18301.1.
AE002161 Genomic DNA. Translation: AAF38440.1.
BA000008 Genomic DNA. Translation: BAA98358.1.
AE009440 Genomic DNA. Translation: AAP98082.1.
PIRA72114.
D81556.
D86509.
RefSeqNP_224356.1. NC_000922.1.
NP_300207.1. NC_002491.1.
NP_445167.1. NC_002179.2.
NP_876425.1. NC_005043.1.

3D structure databases

ProteinModelPortalQ7AJA5.
ModBaseSearch...

Protein-protein interaction databases

STRING115713.CPn0148.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD18301; AAD18301; CPn_0148.
AAF38440; AAF38440; CP_0625.
AAP98082; AAP98082; CpB0149.
BAA98358; BAA98358; BAA98358.
GeneID1466832.
894945.
918939.
963272.
KEGGcpa:CP0625.
cpj:CPj0148.
cpn:CPn0148.
cpt:CpB0149.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000035043.
OMAEGYVNPL.
ProtClustDBCLSK871217.

Enzyme and pathway databases

BioCycCPNE115711:GI7B-623-MONOMER.
CPNE115713:GHEY-151-MONOMER.
CPNE138677:GH8N-144-MONOMER.
CPNE182082:GH4N-150-MONOMER.

Family and domain databases

Gene3D3.90.1580.10. 1 hit.
InterProIPR016187. C-type_lectin_fold.
IPR005532. FGE_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
[Graphical view]
PfamPF03781. FGE-sulfatase. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56436. C-type_lectin_fold. 1 hit.
SSF56112. Kinase_like. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN1_CHLPN
AccessionPrimary (citable) accession number: Q7AJA5
Secondary accession number(s): Q7VQ75, Q9K228, Q9Z935
Entry history
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: July 5, 2004
Last modified: May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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