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Q7AGI4

- Q7AGI4_ECO57

UniProt

Q7AGI4 - Q7AGI4_ECO57

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Protein

Aldose 1-epimerase

Gene

ECs0784

Organism
Escherichia coli O157:H7
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. galactose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BioCyciECOL386585:GJFA-785-MONOMER.
UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Ordered Locus Names:ECs0784Imported
OrganismiEscherichia coli O157:H7Imported
Taxonomic identifieri83334 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000558: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi386585.ECs0784.

Structurei

3D structure databases

ProteinModelPortaliQ7AGI4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

KOiK01785.
OrthoDBiEOG69WFM5.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
TIGRFAMsiTIGR02636. galM_Leloir. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7AGI4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR
60 70 80 90 100
EALLGCASPE CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV
110 120 130 140 150
NQLHGGPEGF DKRRWQIVNQ NDRQVLFALS SDDGDQGFPG NLGATVQYRL
160 170 180 190 200
TDDNRISITY RATVDKPCPV NMTNHVYFNL DGKQSDVRNH KLQILADEYL
210 220 230 240 250
PVDEGGIPHD GLKSVAGTSF DFRSAKIIAS EFLADDDQRK VKGYDHAFLL
260 270 280 290 300
QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNYLG GTPSRGTEPY
310 320 330 340
ADWQGLALES EFLPDSPNHP EWPQPDCFLH PGEEYSSLTE YQFIAE
Length:346
Mass (Da):38,186
Last modified:July 5, 2004 - v1
Checksum:i65A46187B7837597
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000007 Genomic DNA. Translation: BAB34207.1.
RefSeqiNP_308811.1. NC_002695.1.

Genome annotation databases

EnsemblBacteriaiBAB34207; BAB34207; BAB34207.
GeneIDi917521.
KEGGiecs:ECs0784.
PATRICi18374205. VBIEscCol129985_0904.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000007 Genomic DNA. Translation: BAB34207.1 .
RefSeqi NP_308811.1. NC_002695.1.

3D structure databases

ProteinModelPortali Q7AGI4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 386585.ECs0784.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB34207 ; BAB34207 ; BAB34207 .
GeneIDi 917521.
KEGGi ecs:ECs0784.
PATRICi 18374205. VBIEscCol129985_0904.

Phylogenomic databases

KOi K01785.
OrthoDBi EOG69WFM5.

Enzyme and pathway databases

UniPathwayi UPA00242 .
BioCyci ECOL386585:GJFA-785-MONOMER.

Family and domain databases

Gene3Di 2.70.98.10. 1 hit.
InterProi IPR018052. Ald1_epimerase_CS.
IPR013458. Ald_epimerase_bac.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view ]
Pfami PF01263. Aldose_epim. 1 hit.
[Graphical view ]
PIRSFi PIRSF005096. GALM. 1 hit.
SUPFAMi SSF74650. SSF74650. 1 hit.
TIGRFAMsi TIGR02636. galM_Leloir. 1 hit.
PROSITEi PS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12."
    Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T.
    , Kuhara S., Shiba T., Hattori M., Shinagawa H.
    DNA Res. 8:11-22(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: O157:H7 / Sakai / RIMD 0509952 / EHECImported.

Entry informationi

Entry nameiQ7AGI4_ECO57
AccessioniPrimary (citable) accession number: Q7AGI4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 1, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3