SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q7A774

- HPS_STAAN

UniProt

Q7A774 - HPS_STAAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
3-hexulose-6-phosphate synthase
Gene
SA0528
Organism
Staphylococcus aureus (strain N315)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate By similarity.

Catalytic activityi

D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde.

Pathwayi

GO - Molecular functioni

  1. hexulose-6-phosphate synthase activity Source: InterPro
  2. orotidine-5'-phosphate decarboxylase activity Source: InterPro

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. carbohydrate metabolic process Source: UniProtKB-KW
  3. formaldehyde assimilation via ribulose monophosphate cycle Source: UniProtKB-UniPathway
  4. one-carbon metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbohydrate metabolism, One-carbon metabolism

Enzyme and pathway databases

BioCyciSAUR158879:GJCB-562-MONOMER.
UniPathwayiUPA00294; UER00434.

Names & Taxonomyi

Protein namesi
Recommended name:
3-hexulose-6-phosphate synthase (EC:4.1.2.43)
Short name:
HPS
Alternative name(s):
D-arabino-3-hexulose-6-phosphate formaldehyde lyase
Gene namesi
Ordered Locus Names:SA0528
OrganismiStaphylococcus aureus (strain N315)
Taxonomic identifieri158879 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000751: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2102103-hexulose-6-phosphate synthase
PRO_0000269520Add
BLAST

2D gel databases

SWISS-2DPAGEQ7A774.

Interactioni

Protein-protein interaction databases

STRINGi158879.SA0528.

Structurei

3D structure databases

ProteinModelPortaliQ7A774.
SMRiQ7A774. Positions 1-202.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0269.
HOGENOMiHOG000226072.
KOiK08093.
OMAiYIDVVEI.
OrthoDBiEOG66B435.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR017553. 3-hexulose-6-phosphate_synth.
IPR013785. Aldolase_TIM.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR03128. RuMP_HxlA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7A774-1 [UniParc]FASTAAdd to Basket

« Hide

MELQLAIDLL NKEDAAELAN KVKDYVDIVE IGTPIIYNEG LPAVKHMADN    50
ISNVKVLADM KIMDAADYEV SQAIKFGADV ITILGVAEDA SIKAAIEEAH 100
KNNKQLLVDM IAVQDLEKRA KELDEMGADY IAVHTGYDLQ AEGQSPLESL 150
RTVKSVIKNS KVAVAGGIKP DTIKDIVAES PDLVIVGGGI ANADDPVEAA 200
KQCRAAIEGK 210
Length:210
Mass (Da):22,436
Last modified:July 5, 2004 - v1
Checksum:i7C952A812A729538
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000018 Genomic DNA. Translation: BAB41759.1.
PIRiD89825.
RefSeqiNP_373781.1. NC_002745.2.

Genome annotation databases

EnsemblBacteriaiBAB41759; BAB41759; BAB41759.
GeneIDi1123333.
KEGGisau:SA0528.
PATRICi19573168. VBIStaAur116463_0554.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000018 Genomic DNA. Translation: BAB41759.1 .
PIRi D89825.
RefSeqi NP_373781.1. NC_002745.2.

3D structure databases

ProteinModelPortali Q7A774.
SMRi Q7A774. Positions 1-202.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 158879.SA0528.

2D gel databases

SWISS-2DPAGE Q7A774.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB41759 ; BAB41759 ; BAB41759 .
GeneIDi 1123333.
KEGGi sau:SA0528.
PATRICi 19573168. VBIStaAur116463_0554.

Phylogenomic databases

eggNOGi COG0269.
HOGENOMi HOG000226072.
KOi K08093.
OMAi YIDVVEI.
OrthoDBi EOG66B435.

Enzyme and pathway databases

UniPathwayi UPA00294 ; UER00434 .
BioCyci SAUR158879:GJCB-562-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR017553. 3-hexulose-6-phosphate_synth.
IPR013785. Aldolase_TIM.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR03128. RuMP_HxlA. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: N315.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: N315.
  3. "Shotgun proteomic analysis of total and membrane protein extracts of S. aureus strain N315."
    Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.
    Submitted (OCT-2007) to UniProtKB
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: N315.

Entry informationi

Entry nameiHPS_STAAN
AccessioniPrimary (citable) accession number: Q7A774
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: July 5, 2004
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi