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Q7A5Z8

- Q7A5Z8_STAAN

UniProt

Q7A5Z8 - Q7A5Z8_STAAN

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Protein
Submitted name: Protein kinase
Gene
SA1063
Organism
Staphylococcus aureus (strain N315)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi429 – 4291ZincImported
Metal bindingi432 – 4321ZincImported

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. penicillin binding Source: InterPro
  4. protein serine/threonine kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Metal-bindingImported, Nucleotide-binding, ZincImported

Enzyme and pathway databases

BioCyciSAUR158879:GJCB-1123-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein kinaseImported
Gene namesi
Ordered Locus Names:SA1063Imported
OrganismiStaphylococcus aureus (strain N315)Imported
Taxonomic identifieri158879 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000751: Chromosome

PTM / Processingi

PTM databases

PhosSiteiP0909763.

Interactioni

Protein-protein interaction databases

STRINGi158879.SA1063.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3M9GX-ray2.90A376-576[»]
4EQMX-ray3.00A/B/C/D/E/F1-291[»]
ProteinModelPortaliQ7A5Z8.
SMRiQ7A5Z8. Positions 1-282, 376-662.

Miscellaneous databases

EvolutionaryTraceiQ7A5Z8.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037186.
KOiK08884.
OMAiMQIPIVN.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7A5Z8-1 [UniParc]FASTAAdd to Basket

« Hide

MIGKIINERY KIVDKLGGGG MSTVYLAEDT ILNIKVAIKA IFIPPREKEE    50
TLKRFEREVH NSSQLSHQNI VSMIDVDEED DCYYLVMEYI EGPTLSEYIE 100
SHGPLSVDTA INFTNQILDG IKHAHDMRIV HRDIKPQNIL IDSNKTLKIF 150
DFGIAKALSE TSLTQTNHVL GTVQYFSPEQ AKGEATDECT DIYSIGIVLY 200
EMLVGEPPFN GETAVSIAIK HIQDSVPNVT TDVRKDIPQS LSNVILRATE 250
KDKANRYKTI QEMKDDLSSV LHENRANEDV YELDKMKTIA VPLKKEDLAK 300
HISEHKSNQP KRETTQVPIV NGPAHHQQFQ KPEGTVYEPK PKKKSTRKIV 350
LLSLIFSLLM IALVSFVAMA MFGNKYEETP DVIGKSVKEA EQIFNKNNLK 400
LGKISRSYSD KYPENEIIKT TPNTGERVER GDSVDVVISK GPEKVKMPNV 450
IGLPKEEALQ KLKSLGLKDV TIEKVYNNQA PKGYIANQSV TANTEIAIHD 500
SNIKLYESLG IKQVYVEDFE HKSFSKAKKA LEEKGFKVES KEEYSDDIDE 550
GDVISQSPKG KSVDEGSTIS FVVSKGKKSD SSDVKTTTES VDVPYTGKND 600
KSQKVKVYIK DKDNDGSTEK GSFDITSDQR IDIPLRIEKG KTASYIVKVD 650
GKTVAEKEVS YDDI 664
Length:664
Mass (Da):74,377
Last modified:July 5, 2004 - v1
Checksum:i3461386C5DB61828
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000018 Genomic DNA. Translation: BAB42315.1.
RefSeqiNP_374336.1. NC_002745.2.

Genome annotation databases

EnsemblBacteriaiBAB42315; BAB42315; BAB42315.
GeneIDi1123894.
KEGGisau:SA1063.
PATRICi19574346. VBIStaAur116463_1142.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000018 Genomic DNA. Translation: BAB42315.1 .
RefSeqi NP_374336.1. NC_002745.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3M9G X-ray 2.90 A 376-576 [» ]
4EQM X-ray 3.00 A/B/C/D/E/F 1-291 [» ]
ProteinModelPortali Q7A5Z8.
SMRi Q7A5Z8. Positions 1-282, 376-662.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 158879.SA1063.

PTM databases

PhosSitei P0909763.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB42315 ; BAB42315 ; BAB42315 .
GeneIDi 1123894.
KEGGi sau:SA1063.
PATRICi 19574346. VBIStaAur116463_1142.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037186.
KOi K08884.
OMAi MQIPIVN.
OrthoDBi EOG6B35XT.

Enzyme and pathway databases

BioCyci SAUR158879:GJCB-1123-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q7A5Z8.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 3 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 3 hits.
SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 3 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: N315Imported.
  2. "The extended conformation of the 2.9-A crystal structure of the three-PASTA domain of a Ser/Thr kinase from the human pathogen Staphylococcus aureus."
    Paracuellos P., Ballandras A., Robert X., Kahn R., Herve M., Mengin-Lecreulx D., Cozzone A.J., Duclos B., Gouet P.
    J. Mol. Biol. 404:847-858(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) OF 376-576 IN COMPLEX WITH ZINC.
  3. "Structural analysis of Staphylococcus aureus serine/threonine kinase PknB."
    Rakette S., Donat S., Ohlsen K., Stehle T.
    PLoS ONE 7:e39136-e39136(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS) OF 1-291.

Entry informationi

Entry nameiQ7A5Z8_STAAN
AccessioniPrimary (citable) accession number: Q7A5Z8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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