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Q7A4D8

- ALD1_STAAN

UniProt

Q7A4D8 - ALD1_STAAN

Protein

Putative aldehyde dehydrogenase SA1924

Gene

SA1924

Organism
Staphylococcus aureus (strain N315)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei245 – 2451By similarity
    Active sitei279 – 2791By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi201 – 2077NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSAUR158879:GJCB-2057-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase SA1924 (EC:1.2.1.3)
    Gene namesi
    Ordered Locus Names:SA1924
    OrganismiStaphylococcus aureus (strain N315)
    Taxonomic identifieri158879 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000000751: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Putative aldehyde dehydrogenase SA1924PRO_0000293558Add
    BLAST

    Proteomic databases

    PRIDEiQ7A4D8.

    2D gel databases

    SWISS-2DPAGEQ7A4D8.

    Interactioni

    Protein-protein interaction databases

    STRINGi158879.SA1924.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7A4D8.
    SMRiQ7A4D8. Positions 1-475.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiIDENRAA.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7A4D8-1 [UniParc]FASTAAdd to Basket

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    MRDYTKQYIN GEWVESNSNE TIEVINPATE EVIGKVAKGN KADVDKAVEA    50
    ADDVYLEFRH TSVKERQALL DKIVKEYENR KDDIVQAITD ELGAPLSLSE 100
    RVHYQMGLNH FVAARDALDN YEFEERRGDD LVVKEAIGVS GLITPWNFPT 150
    NQTSLKLAAA FAAGSPVVLK PSEETPFAAV ILAEIFDKVG VPKGVFNLVN 200
    GDGAGVGNPL SEHPKVRMMS FTGSGPTGSK IMEKAAKDFK KVSLELGGKS 250
    PYIVLDDVDI KEAAKATTGK VVNNTGQVCT AGTRVLVPNK IKDAFLAELK 300
    EQFSQVRVGN PREDGTQVGP IISKKQFDQV QNYINKGIEE GAELFYGGPG 350
    KPEGLEKGYF ARPTIFINVD NQMTIAQEEI FGPVMSVITY NDLDEAIQIA 400
    NDTKYGLAGY VIGKDKETLH KVARSIEAGT VEINEAGRKP DLPFGGYKQS 450
    GLGREWGDYG IEEFLEVKSI AGYFK 475
    Length:475
    Mass (Da):51,969
    Last modified:July 5, 2004 - v1
    Checksum:i03C66ED0B87BC09A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000018 Genomic DNA. Translation: BAB43208.1.
    PIRiG90005.
    RefSeqiNP_375229.1. NC_002745.2.

    Genome annotation databases

    EnsemblBacteriaiBAB43208; BAB43208; BAB43208.
    GeneIDi1124825.
    KEGGisau:SA1924.
    PATRICi19576306. VBIStaAur116463_2080.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000018 Genomic DNA. Translation: BAB43208.1 .
    PIRi G90005.
    RefSeqi NP_375229.1. NC_002745.2.

    3D structure databases

    ProteinModelPortali Q7A4D8.
    SMRi Q7A4D8. Positions 1-475.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 158879.SA1924.

    2D gel databases

    SWISS-2DPAGE Q7A4D8.

    Proteomic databases

    PRIDEi Q7A4D8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB43208 ; BAB43208 ; BAB43208 .
    GeneIDi 1124825.
    KEGGi sau:SA1924.
    PATRICi 19576306. VBIStaAur116463_2080.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi IDENRAA.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci SAUR158879:GJCB-2057-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: N315.
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY.
      Strain: N315.
    3. "Shotgun proteomic analysis of total and membrane protein extracts of S. aureus strain N315."
      Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.
      Submitted (OCT-2007) to UniProtKB
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Strain: N315.

    Entry informationi

    Entry nameiALD1_STAAN
    AccessioniPrimary (citable) accession number: Q7A4D8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3