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Q7A4C3

- Q7A4C3_STAAN

UniProt

Q7A4C3 - Q7A4C3_STAAN

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Protein
Submitted name: Repressor protein
Gene
czrA
Organism
Staphylococcus aureus (strain N315)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi84 – 841ZincImported
Metal bindingi86 – 861Zinc; via pros nitrogenImported
Metal bindingi97 – 971Zinc; via pros nitrogenImported
Metal bindingi100 – 1001Zinc; via tele nitrogenImported

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation, Metal-bindingImported, ZincImported

Enzyme and pathway databases

BioCyciSAUR158879:GJCB-2080-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Repressor proteinImported
Gene namesi
Name:czrAImported
OrganismiStaphylococcus aureus (strain N315)Imported
Taxonomic identifieri158879 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000000751: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi158879.SA1947.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4GGGX-ray2.00A/B3-106[»]
ProteinModelPortaliQ7A4C3.
SMRiQ7A4C3. Positions 6-103.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0640.
HOGENOMiHOG000144506.
OMAiINVESNQ.
OrthoDBiEOG6Z3KS4.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
[Graphical view]
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7A4C3-1 [UniParc]FASTAAdd to Basket

« Hide

MSEQYSEINT DTLERVTEIF KALGDYNRIR IMELLSVSEA SVGHISHQLN    50
LSQSNVSHQL KLLKSVHLVK AKRQGQSMIY SLDDIHVATM LKQAIHHANH 100
PKESGL 106
Length:106
Mass (Da):11,989
Last modified:July 5, 2004 - v1
Checksum:iD3EB24D10D5EA4BC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000018 Genomic DNA. Translation: BAB43231.1.
RefSeqiNP_375252.1. NC_002745.2.

Genome annotation databases

EnsemblBacteriaiBAB43231; BAB43231; BAB43231.
GeneIDi1124848.
KEGGisau:SA1947.
PATRICi19576352. VBIStaAur116463_2103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000018 Genomic DNA. Translation: BAB43231.1 .
RefSeqi NP_375252.1. NC_002745.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4GGG X-ray 2.00 A/B 3-106 [» ]
ProteinModelPortali Q7A4C3.
SMRi Q7A4C3. Positions 6-103.
ModBasei Search...

Protein-protein interaction databases

STRINGi 158879.SA1947.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB43231 ; BAB43231 ; BAB43231 .
GeneIDi 1124848.
KEGGi sau:SA1947.
PATRICi 19576352. VBIStaAur116463_2103.

Phylogenomic databases

eggNOGi COG0640.
HOGENOMi HOG000144506.
OMAi INVESNQ.
OrthoDBi EOG6Z3KS4.

Enzyme and pathway databases

BioCyci SAUR158879:GJCB-2080-MONOMER.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
PRINTSi PR00778. HTHARSR.
SMARTi SM00418. HTH_ARSR. 1 hit.
[Graphical view ]
PROSITEi PS50987. HTH_ARSR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: N315Imported.
  2. "Allosteric inhibition of a zinc-sensing transcriptional repressor: insights into the arsenic repressor (ArsR) family."
    Campanello G.C., Ma Z., Grossoehme N.E., Guerra A.J., Ward B.P., Dimarchi R.D., Ye Y., Dann C.E., Giedroc D.P.
    J. Mol. Biol. 425:1143-1157(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 3-106 IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ7A4C3_STAAN
AccessioniPrimary (citable) accession number: Q7A4C3
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome

External Data

Dasty 3

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