Q7A3F7 (Q7A3F7_STAAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydroxymethylglutaryl-CoA reductase EMBL BAB43636.1

Gene names

Name:	mvaA EMBL BAB43636.1
Ordered Locus Names:	SA2333

Organism

Staphylococcus aureus (strain N315) [Complete proteome] [HAMAP]

Taxonomic identifier

158879 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	425 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004269
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7A3F7 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 2FFBED86F2B7B877	FASTA	425	46,181
	10 20 30 40 50 60 MQSLDKNFRH LSRQQKLQQL VDKQWLSEDQ FDILLNHPLI DEEVANSLIE NVIAQGALPV 70 80 90 100 110 120 GLLPNIIVDD KAYVVPMMVE EPSVVAAASY GAKLVNQTGG FKTVSSERIM IGQIVFDGVD 130 140 150 160 170 180 DTEKLSADIK ALEKQIHKIA DEAYPSIKAR GGGYQRIAID TFPEQQLLSL KVFVDTKDAM 190 200 210 220 230 240 GANMLNTILE AITAFLKNES PQSDILMSIL SNHATASVVK VQGEIDVKDL ARGERTGEEV 250 260 270 280 290 300 AKRMERASVL AQVDIHRAAT HNKGVMNGIH AVVLATGNDT RGAEASAHAY ASRDGQYRGI 310 320 330 340 350 360 ATWRYDQKRQ RLIGTIEVPM TLAIVGGGTK VLPIAKASLE LLNVDSAQEL GHVVAAVGLA 370 380 390 400 410 420 QNFAACRALV SEGIQQGHMS LQYKSLAIVV GAKGDEIAQV AEALKQEPRA NTQVAERILQ EIRQQ

References

[1]

"Whole genome sequencing of meticillin-resistant Staphylococcus aureus." Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L., Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M., Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y. , Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H., Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K., Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H., Hiramatsu K. Lancet (Lond.) 357:1225-1240(2001) [PubMed: 11418146] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000018 Genomic DNA. Translation: BAB43636.1.
RefSeq	NP_375657.1. NC_002745.2.
3D structure databases
ProteinModelPortal	Q7A3F7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7A3F7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000002063; EBSTAP00000002063; EBSTAG00000002063.
GeneID	1125260.
GenomeReviews	Gene locus SA2333 in contig BA000018_GR.
KEGG	sau:SA2333.
PATRIC	19577224. VBIStaAur116463_2530.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1257.
GeneTree	EBGT00050000024128.
HOGENOM	HBG477902.
OMA	NNKGIMN.
PhylomeDB	Q7A3F7.
ProtClustDB	CLSK886059.
Enzyme and pathway databases
BioCyc	SAUR158879:SA2333-MONOMER.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00066. HMG_COA_REDUCTASE_1. 1 hit. PS01192. HMG_COA_REDUCTASE_3. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7A3F7_STAAN

Accession

Primary (citable) accession number: Q7A3F7

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)