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Protein

Putative acetyl-CoA C-acetyltransferase VraB

Gene

vraB

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Miscellaneous

May contribute to vancomycin resistance.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei86Acyl-thioester intermediateBy similarity1
Active sitei338Proton acceptorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative acetyl-CoA C-acetyltransferase VraB (EC:2.3.1.-)
Gene namesi
Name:vraB
Ordered Locus Names:SAV0576
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002064271 – 379Putative acetyl-CoA C-acetyltransferase VraBAdd BLAST379

Proteomic databases

PaxDbiQ7A2W9

Interactioni

Protein-protein interaction databases

STRINGi158878.SAV0576

Structurei

3D structure databases

ProteinModelPortaliQ7A2W9
SMRiQ7A2W9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thiolase family.Curated

Phylogenomic databases

eggNOGiENOG4105CHU Bacteria
COG0183 LUCA
HOGENOMiHOG000012239
KOiK00626
OMAiGHPWGAS
PhylomeDBiQ7A2W9

Family and domain databases

CDDicd00751 thiolase, 1 hit
Gene3Di3.40.47.10, 4 hits
InterProiView protein in InterPro
IPR002155 Thiolase
IPR016039 Thiolase-like
IPR020617 Thiolase_C
IPR020613 Thiolase_CS
IPR020616 Thiolase_N
PfamiView protein in Pfam
PF02803 Thiolase_C, 1 hit
PF00108 Thiolase_N, 1 hit
PIRSFiPIRSF000429 Ac-CoA_Ac_transf, 1 hit
SUPFAMiSSF53901 SSF53901, 2 hits
TIGRFAMsiTIGR01930 AcCoA-C-Actrans, 1 hit
PROSITEiView protein in PROSITE
PS00737 THIOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7A2W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQAVIVAAK RTAFGKYGGT LKHLEPEQLL KPLFQHFKEK YPEVISKIDD
60 70 80 90 100
VVLGNVVGNG GNIARKALLE AGLKDSIPGV TIDRQCGSGL ESVQYACRMI
110 120 130 140 150
QAGAGKVYIA GGVESTSRAP WKIKRPHSVY ETALPEFYER ASFAPEMSDP
160 170 180 190 200
SMIQGAENVA KMYDVSRELQ DEFAYRSHQL TAENVKNGNI SQEILPITVK
210 220 230 240 250
GEIFNTDESL KSHIPKDNFG RFKPVIKGGT VTAANSCMKN DGAVLLLIME
260 270 280 290 300
KDMAYELGFE HGLLFKDGVT VGVDSNFPGI GPVPAISNLL KRNQLTIENI
310 320 330 340 350
EVIEINEAFS AQVVACQQAL NISNTQLNIW GGALASGHPY GASGAQLVTR
360 370
LFYMFDKETM IASMGIGGGL GNAALFTRF
Length:379
Mass (Da):41,094
Last modified:July 5, 2004 - v1
Checksum:iB62F36E0A437A771
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB56738.1
RefSeqiWP_001070676.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB56738; BAB56738; SAV0576
KEGGisav:SAV0576

Similar proteinsi

Entry informationi

Entry nameiVRAB_STAAM
AccessioniPrimary (citable) accession number: Q7A2W9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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