ID   Q7A2H3_NOSS1            Unreviewed;       546 AA.
AC   Q7A2H3;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAB72700.1};
GN   Name=cyaD {ECO:0000313|EMBL:BAB72700.1};
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690 {ECO:0000313|EMBL:BAB72700.1, ECO:0000313|Proteomes:UP000002483};
RN   [1] {ECO:0000313|EMBL:BAB72700.1, ECO:0000313|Proteomes:UP000002483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576
RC   {ECO:0000313|Proteomes:UP000002483};
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
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DR   EMBL; BA000019; BAB72700.1; -; Genomic_DNA.
DR   RefSeq; WP_010994917.1; NZ_RSCN01000006.1.
DR   AlphaFoldDB; Q7A2H3; -.
DR   STRING; 103690.gene:10492754; -.
DR   KEGG; ana:all0743; -.
DR   eggNOG; COG1716; Bacteria.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG2203; Bacteria.
DR   OrthoDB; 337251at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd00060; FHA; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00065; GAF; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002483}.
FT   DOMAIN          24..74
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          361..491
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   546 AA;  60870 MW;  5EAFA4D7DA03C2F0 CRC64;
     MTELTLRLQQ GDTETTVTVN RDVFTIGRLP ECNLYLPFAG VSRKHAQLVK KADGKWIIED
     LGSKNGTQVN QSIVSHPRQL QHGDVIWLGN VNLVVLLQTP LTVVSIKPVQ PSDVGEQRTI
     FRSAKQLQQQ WIEANSDDGD ISNKNKTIAR LKDLVDIAKN LCAAASIEEI FFQVQQVVFR
     YLGSIDRLAL LIDVNGCGHL ELVNAGTRSK TQQQYLLADA SWISRSICQK VFEEKIVIQT
     ADTHKDERFS SEHSILLKGI RSAMAVPLWD ENKVVGVLYA DAHLSSYHWE RDGEEELSFF
     SALANLVASS VQRWLLAEKL KTEEVIRHRL ERYHSPAVVQ QLISIGGLPD GRLPPAESEI
     SILFADLVGF TAISERLTPT AIAQLLNNLF EEMLQEVFAC GGTLDKYIGD CIMAFFGAPE
     PQADHADRAT AAAKAMLIRM EHLNANGFWQ EPLQLRIAIN SGKAVVGDVG SSQRVEYTAL
     GGTINLAARM EAICPPSECV ISEATYELLS QRYDFQKMGD YRFKGIDRLV KVYQTKLQQV
     TTIINH
//