ID   Q7A2G7_NOSS1            Unreviewed;       735 AA.
AC   Q7A2G7;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAB73075.1};
GN   Name=cyaA {ECO:0000313|EMBL:BAB73075.1};
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690 {ECO:0000313|EMBL:BAB73075.1, ECO:0000313|Proteomes:UP000002483};
RN   [1] {ECO:0000313|EMBL:BAB73075.1, ECO:0000313|Proteomes:UP000002483}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576
RC   {ECO:0000313|Proteomes:UP000002483};
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
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DR   EMBL; BA000019; BAB73075.1; -; Genomic_DNA.
DR   RefSeq; WP_010995291.1; NZ_RSCN01000008.1.
DR   AlphaFoldDB; Q7A2G7; -.
DR   STRING; 103690.gene:10493132; -.
DR   KEGG; ana:all1118; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   OrthoDB; 337251at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002483};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        358..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          443..575
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   735 AA;  80756 MW;  84057BACFBBFA8C6 CRC64;
     MIWAKLKPLF WQWRGVVFAV PSMTILVIGL RLTGLLQLLE LAALDQFFLL RPPEPPDTRI
     VIVEINEADV RKQTQWPMSD AAMASVLDTI KQQQPRAIGL DIYRDLPVNP GHETLVKLFA
     STPNLIGVQK LSDTRDSSAV NAAPVLKENN QIGSNDLPLD GDGKIRRGLL YVNVNEEDVL
     ESFALKLALL YLKPEKITEK PAASNPNYLQ LNHGVFPIFE ANDGGYVRAD ARSYQILLNY
     RGRIQQFTTV TLNQVQQKQI PADLMRGKVV LIGATAESLK DIFYTPYSSN LFTPPERMAG
     VTIHANLVSQ ILSAALDSRP QIQTLPETGE WLLILVWSII GASLCWQQRS SKNQKIVLAV
     GIPLIGGVVI AGSLLAFVAG WWIPIVPSLL AFGGSAIAVT LYIAQSAGEM RKNLGRYLTD
     EVLANILETP SGLKLGGERR KVTLLFSDLR GFSAMSEQLS PEQVVQILNL YLGVMTDVIN
     QYKGTINEFI GDGIFIMFGA PICRPDDSQR AIACAIAMQR AMQQVNAKTH QMNLPQLEMG
     IGINTGEVVA GNIGSQKRAQ YTVIGSHVNL AARIETYTVG GQILISENTR QDANTDLQIA
     GQMQIEPKGI KEPITIYEIS GIGGAYNLSL PEDNDLMVKL QSPVPVEYQV LQGKQAVGEV
     FRGELVSVSE KKALLHSPHT LEKLANLKLK LLHKPELATA DIYAKVMKQS DADLFVIRFT
     NIPPQAIASL NSLHQ
//