Q7A1A1 (Q7A1A1_STAAW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADPH] PIRNR PIRNR000094
Short name=ENR PIRNR PIRNR000094
EC=1.3.1.10 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL BAB94757.1
Ordered Locus Names:	MW0892

Organism

Staphylococcus aureus (strain MW2) [Complete proteome] [HAMAP]

Taxonomic identifier

196620 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADPH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: InterPro enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	157	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	Q7A1A1 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: 69487F3F410B9A15	FASTA	256	27,992
	10 20 30 40 50 60 MLNLENKTYV IMGIANKRSI AFGVAKVLDQ LGAKLVFTYR KERSRKELEK LLEQLNQPEA 70 80 90 100 110 120 HLYQIDVQSD EEVINGFEQI GKDVGNIDGV YHSIAFANME DLRGRFSETS REGFLLAQDI 130 140 150 160 170 180 SSYSLTIVAH EAKKLMPEGG SIVATTYLGG EFAVQNYNVM GVAKASLEAN VKYLALDLGP 190 200 210 220 230 240 DNIRVNAISA GPIRTLSAKG VGGFNTILKE IEERAPLKRN VDQVEVGKTA AYLLSDLSSG 250 VTGENIHVDS GFHAIK

References

[1]	"Genome and virulence determinants of high virulence community-acquired MRSA." Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K. Lancet 359:1819-1827(2002) [PubMed: 12044378] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000033 Genomic DNA. Translation: BAB94757.1.
RefSeq	NP_645709.1. NC_003923.1.
3D structure databases
ProteinModelPortal	Q7A1A1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7A1A1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000026358; EBSTAP00000025397; EBSTAG00000026357.
GeneID	1003004.
GenomeReviews	Gene locus MW0892 in contig BA000033_GR.
KEGG	sam:MW0892.
PATRIC	19568351. VBIStaAur44266_0937.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
GeneTree	EBGT00050000023865.
HOGENOM	HBG750976.
OMA	KKWDGLD.
PhylomeDB	Q7A1A1.
ProtClustDB	PRK08594.
Enzyme and pathway databases
BioCyc	SAUR196620:MW0892-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

Q7A1A1_STAAW

Accession

Primary (citable) accession number: Q7A1A1

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)