Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Aerobic glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

FADBy similarity

Pathwayi: glycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (aerobic route).
Proteins known to be involved in this subpathway in this organism are:
  1. Aerobic glycerol-3-phosphate dehydrogenase (glpD)
This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes glycerone phosphate from sn-glycerol 3-phosphate (aerobic route), the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 49FADSequence analysisAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processGlycerol metabolism
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00618; UER00674

Names & Taxonomyi

Protein namesi
Recommended name:
Aerobic glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:MW1184
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000418 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002700641 – 557Aerobic glycerol-3-phosphate dehydrogenaseAdd BLAST557

Structurei

3D structure databases

ProteinModelPortaliQ7A105
SMRiQ7A105
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000004812
KOiK00111

Family and domain databases

Gene3Di1.10.8.870, 1 hit
3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR031656 DAO_C
IPR038299 DAO_C_sf
IPR006076 FAD-dep_OxRdtase
IPR036188 FAD/NAD-bd_sf
IPR000447 G3P_DH_FAD-dep
PANTHERiPTHR11985 PTHR11985, 1 hit
PfamiView protein in Pfam
PF01266 DAO, 1 hit
PF16901 DAO_C, 1 hit
PRINTSiPR01001 FADG3PDH
SUPFAMiSSF51905 SSF51905, 2 hits
PROSITEiView protein in PROSITE
PS00977 FAD_G3PDH_1, 1 hit
PS00978 FAD_G3PDH_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7A105-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSTFKREH IKKNLRNDEY DLVIIGGGIT GAGIALDASE RGMKVALVEM
60 70 80 90 100
QDFAQGTSSR STKLVHGGLR YLKQFQIGVV AETGKERAIV YENGPHVTTP
110 120 130 140 150
EWMLLPMHKG GTFGKFSTSI GLGMYDRLAG VKKSERKKML SKKETLAKEP
160 170 180 190 200
LVKKEGLKGG GYYVEYRTDD ARLTIEVMKR AAEKGAEIIN YTKSEHFTYD
210 220 230 240 250
KNQQVNGVKV IDKLTNENYT IKAKKVVNAA GPWVDDVRSG DYARNNKKLR
260 270 280 290 300
LTKGVHVVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD
310 320 330 340 350
NIKSSPLTTQ EDRDYLIDAI NYMFPSVNVT DEDIESTWAG IRPLIYEEGK
360 370 380 390 400
DPSEISRKDE IWEGKSGLLT IAGGKLTGYR HMAQDIVDLV SKRLKKDYGL
410 420 430 440 450
TFSPCNTKGL AISGGDVGGS KNFDAFVEQK VDVAKGFGID EDVARRLASK
460 470 480 490 500
YGSNVDELFN IAQTSQYHDS KLPLEIYVEL VYSIQQEMVY KPNDFLVRRS
510 520 530 540 550
GKMYFNIKDV LDYKDAVIDI MADMLDYSPA QIEAYTEEVE QAIKEAQHGN

NQPAVKE
Length:557
Mass (Da):62,388
Last modified:January 9, 2007 - v2
Checksum:iBB3D044040212E82
GO

Sequence cautioni

The sequence BAB95049 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA Translation: BAB95049.1 Different initiation.
RefSeqiWP_001218596.1, NC_003923.1

Genome annotation databases

EnsemblBacteriaiBAB95049; BAB95049; BAB95049
KEGGisam:MW1184

Entry informationi

Entry nameiGLPD_STAAW
AccessioniPrimary (citable) accession number: Q7A105
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 83 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health