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Protein

Low molecular weight protein-tyrosine-phosphatase PtpA

Gene

ptpA

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Dephosphorylates the phosphotyrosine-containing proteins.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei8NucleophileBy similarity1
Active sitei14By similarity1
Active sitei120Proton donorBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase PtpA (EC:3.1.3.48)
Alternative name(s):
Phosphotyrosine phosphatase A
Short name:
PTPase A
Gene namesi
Name:ptpA
Ordered Locus Names:MW1821
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000418 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003006621 – 154Low molecular weight protein-tyrosine-phosphatase PtpAAdd BLAST154

Structurei

3D structure databases

ProteinModelPortaliQ7A0I2.
SMRiQ7A0I2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000273094.
KOiK01104.
OMAiAGTGSWH.

Family and domain databases

InterProiView protein in InterPro
IPR023485. Ptyr_pPase.
IPR036196. Ptyr_pPase_sf.
IPR017867. Tyr_phospatase_low_mol_wt.
PfamiView protein in Pfam
PF01451. LMWPc. 1 hit.
PRINTSiPR00719. LMWPTPASE.
SMARTiView protein in SMART
SM00226. LMWPc. 1 hit.
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7A0I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDVAFVCLG NICRSPMAEA IMRQRLKDRN IHDIKVHSRG TGSWNLGEPP
60 70 80 90 100
HEGTQKILNK HNIPFDGMIS ELFEATDDFD YIVAMDQSNV DNIKSINPNL
110 120 130 140 150
KGQLFKLLEF SNMEESDVPD PYYTNNFEGV YDMVLSSCDN LIDYIVKDAN

LKEG
Length:154
Mass (Da):17,491
Last modified:July 5, 2004 - v1
Checksum:i67E81E0B8125B1E8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA. Translation: BAB95686.1.
RefSeqiWP_000228666.1. NC_003923.1.

Genome annotation databases

EnsemblBacteriaiBAB95686; BAB95686; BAB95686.
KEGGisam:MW1821.

Similar proteinsi

Entry informationi

Entry nameiPTPA_STAAW
AccessioniPrimary (citable) accession number: Q7A0I2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families