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Protein

Oxygen regulatory protein NreC

Gene

nreC

Organism
Staphylococcus aureus (strain MW2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi172 – 191H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation, Two-component regulatory system

Names & Taxonomyi

Protein namesi
Recommended name:
Oxygen regulatory protein NreC
Alternative name(s):
Nitrogen regulation protein C
Gene namesi
Name:nreC
Ordered Locus Names:MW2313
OrganismiStaphylococcus aureus (strain MW2)
Taxonomic identifieri196620 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000418 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003493501 – 217Oxygen regulatory protein NreCAdd BLAST217

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei534-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by NreB.By similarity

Keywords - PTMi

Phosphoprotein

Structurei

3D structure databases

ProteinModelPortaliQ7A029
SMRiQ7A029
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 119Response regulatoryPROSITE-ProRule annotationAdd BLAST118
Domaini148 – 213HTH luxR-typePROSITE-ProRule annotationAdd BLAST66

Phylogenomic databases

HOGENOMiHOG000034813
KOiK07696
OMAiSKSESFY

Family and domain databases

CDDicd06170 LuxR_C_like, 1 hit
cd00156 REC, 1 hit
InterProiView protein in InterPro
IPR011006 CheY-like_superfamily
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR001789 Sig_transdc_resp-reg_receiver
IPR000792 Tscrpt_reg_LuxR_C
PfamiView protein in Pfam
PF00196 GerE, 1 hit
PF00072 Response_reg, 1 hit
PRINTSiPR00038 HTHLUXR
SMARTiView protein in SMART
SM00421 HTH_LUXR, 1 hit
SM00448 REC, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF52172 SSF52172, 1 hit
PROSITEiView protein in PROSITE
PS00622 HTH_LUXR_1, 1 hit
PS50043 HTH_LUXR_2, 1 hit
PS50110 RESPONSE_REGULATORY, 1 hit

Sequencei

Sequence statusi: Complete.

Q7A029-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIVIADDHA VVRTGFSMIL NYQNDMEVVA TAADGVEAYQ KVMEYKPDVL
60 70 80 90 100
LMDLSMPPGE SGLIATSKIA DSFPETKILI LTMFDDEEYL FHVLRNGAKG
110 120 130 140 150
YILKNAPDEQ LLLAIRTVYK GETYVDMKLT TSLVNEFVSN SNQDTANTTD
160 170 180 190 200
PFKILSKREL EILPLIAKGY GNKEIAEKLF VSVKTVEAHK THIMTKLGLK
210
SKPELVEYAL KKKLLEF
Length:217
Mass (Da):24,368
Last modified:July 5, 2004 - v1
Checksum:iDDF2969C5B277320
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000033 Genomic DNA Translation: BAB96178.1
RefSeqiWP_000706315.1, NC_003923.1

Genome annotation databases

EnsemblBacteriaiBAB96178; BAB96178; BAB96178
KEGGisam:MW2313

Similar proteinsi

Entry informationi

Entry nameiNREC_STAAW
AccessioniPrimary (citable) accession number: Q7A029
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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