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Protein

Flagellar transcriptional regulator FlhD

Gene

setD

Organism
Vibrio cholerae
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorSAAS annotation, DNA-bindingSAAS annotation
Biological processBacterial flagellum biogenesisSAAS annotation, Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar transcriptional regulator FlhDSAAS annotation
Gene namesi
Name:setDImported
OrganismiVibrio choleraeImported
Taxonomic identifieri666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Subcellular locationi

Q79S40:
  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Subunit structurei

Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.SAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the FlhD family.SAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR023559. Flagellar_FlhD.
IPR036194. FlhD_sf.
PfamiView protein in Pfam
PF05247. FlhD. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD015582. Flagellar_transcriptional_act. 1 hit.
SUPFAMiSSF63592. SSF63592. 1 hit.

Sequencei

Sequence statusi: Complete.

Q79S40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTNQQDFYQ LNLAYLHAAR ELARIDPQEA VLRFGLTRDV VDALINAGVD
60 70 80 90
DLQRVATSSF MLFQPRGNQS QLIEMVKSKG TGIPRIAYLL STLNNKGDA
Length:99
Mass (Da):11,026
Last modified:July 5, 2004 - v1
Checksum:i03FF2DD751D44DF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY055428 Genomic DNA. Translation: AAL67891.1.
KT151654 Genomic DNA. Translation: ALP44314.1.
KT151655 Genomic DNA. Translation: ALP44401.1.
KT151656 Genomic DNA. Translation: ALP44495.1.
KT151657 Genomic DNA. Translation: ALP44581.1.
KT151658 Genomic DNA. Translation: ALP44673.1.
KT151659 Genomic DNA. Translation: ALP44766.1.
KT151661 Genomic DNA. Translation: ALP44950.1.
KT151662 Genomic DNA. Translation: ALP45037.1.
CGII01000025 Genomic DNA. Translation: CPR24609.1.
CGIJ01000025 Genomic DNA. Translation: CPR24610.1.
RefSeqiWP_000210563.1. NZ_NEDW01000002.1.

Genome annotation databases

GeneIDi6802413.
PATRICifig|666.1966.peg.2663.

Similar proteinsi

Entry informationi

Entry nameiQ79S40_VIBCL
AccessioniPrimary (citable) accession number: Q79S40
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: October 25, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)