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Q79PF4

- KAIC_SYNE7

UniProt

Q79PF4 - KAIC_SYNE7

Protein

Circadian clock protein kinase KaiC

Gene

kaiC

Organism
Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 97 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction.2 Publications

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Cofactori

    Magnesium.1 Publication

    Enzyme regulationi

    The interaction with KaiA enhances its phosphorylation status, while the interaction with KaiB decreases it. A KaiA dimer is sufficient to enhance KaiC phosphorylation.3 Publications

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi295 – 2951Magnesium
    Metal bindingi318 – 3181Magnesium
    Metal bindingi319 – 3191Magnesium
    Metal bindingi378 – 3781Magnesium

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi46 – 538ATP
    Nucleotide bindingi288 – 2958ATP

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. DNA binding Source: UniProtKB-KW
    3. identical protein binding Source: IntAct
    4. magnesium ion binding Source: UniProtKB-HAMAP
    5. protein binding Source: IntAct
    6. protein serine/threonine/tyrosine kinase activity Source: UniProtKB-HAMAP
    7. protein serine/threonine kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. circadian rhythm Source: UniProtKB-HAMAP
    2. entrainment of circadian clock Source: UniProtKB
    3. negative regulation of circadian rhythm Source: UniProtKB
    4. regulation of phosphorelay signal transduction system Source: CACAO
    5. regulation of transcription, DNA-templated Source: UniProtKB-KW
    6. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Repressor, Serine/threonine-protein kinase, Transferase

    Keywords - Biological processi

    Biological rhythms, Transcription, Transcription regulation

    Keywords - Ligandi

    ATP-binding, DNA-binding, Magnesium, Metal-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSYNEL:SYNPCC7942_1216-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Circadian clock protein kinase KaiC (EC:2.7.11.1)
    Gene namesi
    Name:kaiC
    Ordered Locus Names:Synpcc7942_1216
    ORF Names:see0011
    OrganismiSynechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
    Taxonomic identifieri1140 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
    ProteomesiUP000002717: Chromosome

    Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi52 – 521K → A: Induces an arrhythmic phenotype. 1 Publication
    Mutagenesisi71 – 711G → A: Lowers the amplitude and distords the waveform of the circadian rhythm. 1 Publication
    Mutagenesisi87 – 871A → V in kaiC1; shortens the period of the circadian rhythm to 22 hours.
    Mutagenesisi114 – 1141G → A: Extends the period of the circadian rhythm to 27 hours. 1 Publication
    Mutagenesisi115 – 1151Q → A: Abolishes the circadian rhythm. 1 Publication
    Mutagenesisi157 – 1571S → C in kaiC2; extends the period of the circadian rhythm to 29 hours.
    Mutagenesisi215 – 2151R → C in kaiC3; shortens the period of the circadian rhythm to 16 hours and decreases the interaction with KaiA.
    Mutagenesisi236 – 2361P → S in kaiC4; extends the period of the circadian rhythm to 28 hours.
    Mutagenesisi248 – 2481P → L in kaiC6; induces a low amplitude phenotype and decreases the interaction with KaiA.
    Mutagenesisi248 – 2481P → S in kaiC5; induces an arrhythmic phenotype.
    Mutagenesisi253 – 2531R → H in kaiC7; extends the period of the circadian rhythm to 40 hours.
    Mutagenesisi273 – 2731M → I in kaiC8; extends the period of the circadian rhythm to 37 hours.
    Mutagenesisi294 – 2941K → A: Induces a long period phenotype. 1 Publication
    Mutagenesisi321 – 3211R → Q in kaiC9; shortens the period of the circadian rhythm to 21 hours.
    Mutagenesisi409 – 4091T → A in kaiC10; extends the period of the circadian rhythm to 27 hours.
    Mutagenesisi421 – 4211G → R in kaiC11; extends the period of the circadian rhythm to 44 hours and increases the interaction with KaiA.
    Mutagenesisi422 – 4221A → T in kaiC15; able to suppress the kaiA2 extended phenotype.
    Mutagenesisi432 – 4321T → A: Loss of function. 1 Publication
    Mutagenesisi442 – 4421Y → H in kaiC12; extends the period of the circadian rhythm to 60 hours and increases the interaction with KaiA.
    Mutagenesisi460 – 4601G → E in kaiC13; induces an arrhythmic phenotype.
    Mutagenesisi495 – 4951T → A in kaiC14; induces an arrhythmic phenotype.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 519519Circadian clock protein kinase KaiCPRO_0000217782Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei432 – 4321Phosphothreonine; by autocatalysis

    Post-translational modificationi

    Phosphorylated on serine/threonine residues by autocatalysis. Both phosphorylated and unphosphorylated forms exist. Can probably autophosphorylate and autodephosphorylate. Phosphorylated form correlates with clock speed.3 Publications

    Keywords - PTMi

    Phosphoprotein

    PTM databases

    PhosSiteiP0501119.

    Expressioni

    Developmental stagei

    Accumulates in a circadian fashion, peaking at circadian time (CT) 15-18.1 Publication

    Inductioni

    Down-regulated by itself.1 Publication

    Interactioni

    Subunit structurei

    Homohexamer; hexamerization is dependent on ATP-binding. Core component of the KaiABC complex, at least composed of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. Interacts directly with SasA.5 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    itself9EBI-592287,EBI-592287
    kaiAQ79PF617EBI-592287,EBI-592281
    kaiBQ79PF510EBI-592287,EBI-619150
    sasAQ069046EBI-592287,EBI-626872

    Protein-protein interaction databases

    DIPiDIP-33330N.
    IntActiQ79PF4. 3 interactions.
    MINTiMINT-8094424.
    STRINGi1140.Synpcc7942_1216.

    Structurei

    Secondary structure

    1
    519
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi28 – 314
    Beta strandi34 – 374
    Beta strandi40 – 478
    Helixi52 – 6716
    Beta strandi71 – 788
    Helixi80 – 878
    Helixi88 – 903
    Helixi94 – 996
    Beta strandi102 – 1076
    Helixi121 – 13717
    Beta strandi140 – 1456
    Turni148 – 1503
    Turni152 – 1543
    Helixi157 – 17418
    Beta strandi177 – 1837
    Beta strandi185 – 1895
    Beta strandi191 – 1955
    Helixi197 – 2004
    Beta strandi202 – 2109
    Turni212 – 2143
    Beta strandi217 – 2259
    Beta strandi233 – 2408
    Beta strandi243 – 2464
    Turni249 – 2513
    Helixi268 – 2736
    Beta strandi276 – 2816
    Beta strandi283 – 2886
    Helixi294 – 30613
    Turni307 – 3093
    Beta strandi312 – 3198
    Helixi321 – 3299
    Turni330 – 3323
    Helixi335 – 3406
    Beta strandi343 – 3464
    Helixi351 – 3533
    Helixi356 – 36813
    Beta strandi373 – 3786
    Helixi380 – 3834
    Beta strandi385 – 3873
    Helixi389 – 40517
    Beta strandi409 – 4157
    Beta strandi417 – 4204
    Beta strandi423 – 4297
    Turni431 – 4333
    Beta strandi435 – 44511
    Beta strandi448 – 46114
    Beta strandi468 – 4725
    Beta strandi477 – 4826
    Beta strandi486 – 4883
    Helixi489 – 4913
    Turni502 – 5054
    Helixi506 – 5083
    Turni510 – 5123
    Beta strandi514 – 5163

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1TF7X-ray2.80A/B/C/D/E/F1-519[»]
    1U9IX-ray2.80A/B/C/D/E/F1-519[»]
    2GBLX-ray2.80A/B/C/D/E/F1-519[»]
    3DVLX-ray2.80A/B/C/D/E/F1-519[»]
    3JZMX-ray2.90A/B/C/D/E/F1-519[»]
    3K09X-ray3.20A/B/C/D/E/F1-519[»]
    3K0AX-ray3.00A/B/C/D/E/F1-519[»]
    3K0CX-ray3.30A/B/C/D/E/F1-519[»]
    3K0EX-ray3.20A/B/C/D/E/F1-519[»]
    3K0FX-ray3.00A/B/C/D/E/F1-519[»]
    3S1AX-ray3.00A/B/C/D/E/F1-519[»]
    4DUGX-ray3.30A/B/C/D/E/F1-519[»]
    4IJMX-ray3.35A/B/C/D/E/F14-519[»]
    ProteinModelPortaliQ79PF4.
    SMRiQ79PF4. Positions 14-519.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ79PF4.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini19 – 260242KaiC 1Add
    BLAST
    Domaini261 – 493233KaiC 2Add
    BLAST

    Domaini

    The KaiC domains mediate the interaction with KaiA.

    Sequence similaritiesi

    Belongs to the KaiC family.Curated
    Contains 2 kaiC domains.Curated

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG0467.
    HOGENOMiHOG000230416.
    KOiK08482.
    OrthoDBiEOG6ZPSVX.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    HAMAPiMF_01836. KaiC.
    InterProiIPR014774. Circ_KaiC/RadA.
    IPR013503. Circadian_KaiC.
    IPR010624. KaiC_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF06745. KaiC. 2 hits.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    TIGRFAMsiTIGR02655. circ_KaiC. 1 hit.
    PROSITEiPS51146. KAIC. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q79PF4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSAEMTSPN NNSEHQAIAK MRTMIEGFDD ISHGGLPIGR STLVSGTSGT    50
    GKTLFSIQFL YNGIIEFDEP GVFVTFEETP QDIIKNARSF GWDLAKLVDE 100
    GKLFILDASP DPEGQEVVGG FDLSALIERI NYAIQKYRAR RVSIDSVTSV 150
    FQQYDASSVV RRELFRLVAR LKQIGATTVM TTERIEEYGP IARYGVEEFV 200
    SDNVVILRNV LEGERRRRTL EILKLRGTSH MKGEYPFTIT DHGINIFPLG 250
    AMRLTQRSSN VRVSSGVVRL DEMCGGGFFK DSIILATGAT GTGKTLLVSR 300
    FVENACANKE RAILFAYEES RAQLLRNAYS WGMDFEEMER QNLLKIVCAY 350
    PESAGLEDHL QIIKSEINDF KPARIAIDSL SALARGVSNN AFRQFVIGVT 400
    GYAKQEEITG LFTNTSDQFM GAHSITDSHI STITDTIILL QYVEIRGEMS 450
    RAINVFKMRG SWHDKAIREF MISDKGPDIK DSFRNFERII SGSPTRITVD 500
    EKSELSRIVR GVQEKGPES 519
    Length:519
    Mass (Da):58,003
    Last modified:July 5, 2004 - v1
    Checksum:i855DFE131EFFF3CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB010691 Genomic DNA. Translation: BAA37103.1.
    AY120853 Genomic DNA. Translation: AAM82686.1.
    CP000100 Genomic DNA. Translation: ABB57246.1.
    PIRiT44269.
    RefSeqiYP_400233.1. NC_007604.1.

    Genome annotation databases

    EnsemblBacteriaiABB57246; ABB57246; Synpcc7942_1216.
    GeneIDi3773504.
    KEGGisyf:Synpcc7942_1216.
    PATRICi23787739. VBISynElo51371_1398.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB010691 Genomic DNA. Translation: BAA37103.1 .
    AY120853 Genomic DNA. Translation: AAM82686.1 .
    CP000100 Genomic DNA. Translation: ABB57246.1 .
    PIRi T44269.
    RefSeqi YP_400233.1. NC_007604.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1TF7 X-ray 2.80 A/B/C/D/E/F 1-519 [» ]
    1U9I X-ray 2.80 A/B/C/D/E/F 1-519 [» ]
    2GBL X-ray 2.80 A/B/C/D/E/F 1-519 [» ]
    3DVL X-ray 2.80 A/B/C/D/E/F 1-519 [» ]
    3JZM X-ray 2.90 A/B/C/D/E/F 1-519 [» ]
    3K09 X-ray 3.20 A/B/C/D/E/F 1-519 [» ]
    3K0A X-ray 3.00 A/B/C/D/E/F 1-519 [» ]
    3K0C X-ray 3.30 A/B/C/D/E/F 1-519 [» ]
    3K0E X-ray 3.20 A/B/C/D/E/F 1-519 [» ]
    3K0F X-ray 3.00 A/B/C/D/E/F 1-519 [» ]
    3S1A X-ray 3.00 A/B/C/D/E/F 1-519 [» ]
    4DUG X-ray 3.30 A/B/C/D/E/F 1-519 [» ]
    4IJM X-ray 3.35 A/B/C/D/E/F 14-519 [» ]
    ProteinModelPortali Q79PF4.
    SMRi Q79PF4. Positions 14-519.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-33330N.
    IntActi Q79PF4. 3 interactions.
    MINTi MINT-8094424.
    STRINGi 1140.Synpcc7942_1216.

    PTM databases

    PhosSitei P0501119.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABB57246 ; ABB57246 ; Synpcc7942_1216 .
    GeneIDi 3773504.
    KEGGi syf:Synpcc7942_1216.
    PATRICi 23787739. VBISynElo51371_1398.

    Phylogenomic databases

    eggNOGi COG0467.
    HOGENOMi HOG000230416.
    KOi K08482.
    OrthoDBi EOG6ZPSVX.

    Enzyme and pathway databases

    BioCyci SYNEL:SYNPCC7942_1216-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q79PF4.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    HAMAPi MF_01836. KaiC.
    InterProi IPR014774. Circ_KaiC/RadA.
    IPR013503. Circadian_KaiC.
    IPR010624. KaiC_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF06745. KaiC. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    TIGRFAMsi TIGR02655. circ_KaiC. 1 hit.
    PROSITEi PS51146. KAIC. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria."
      Ishiura M., Kutsuna S., Aoki S., Iwasaki H., Andersson C.R., Tanabe A., Golden S.S., Johnson C.H., Kondo T.
      Science 281:1519-1523(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, MUTANTS KAIC1; KAIC2; KAIC3; KAIC4; KAIC5; KAIC6; KAIC7; KAIC8; KAIC9; KAIC10; KAIC11; KAIC12; KAIC13 AND KAIC14.
    2. "Synechococcus elongatus PCC7942 cosmid 7G3."
      Holtman C.K., Sandoval P., Chen Y., Socias T., Mohler B.J., McMurtry S., Gonzalez A., Salinas I., Golden S.S., Youderian P.
      Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942."
      US DOE Joint Genome Institute
      Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
      Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 7942.
    4. "Physical interactions among circadian clock proteins KaiA, KaiB and KaiC in cyanobacteria."
      Iwasaki H., Taniguchi Y., Ishiura M., Kondo T.
      EMBO J. 18:1137-1145(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH KAIA AND KAIB.
    5. "Nucleotide binding and autophosphorylation of the clock protein KaiC as a circadian timing process of cyanobacteria."
      Nishiwaki T., Iwasaki H., Ishiura M., Kondo T.
      Proc. Natl. Acad. Sci. U.S.A. 97:495-499(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: ATP-BINDING, AUTOPHOSPHORYLATION, MUTAGENESIS OF LYS-52; GLY-71; GLY-114; GLN-115 AND LYS-294.
    6. "A kaiC-interacting sensory histidine kinase, SasA, necessary to sustain robust circadian oscillation in cyanobacteria."
      Iwasaki H., Williams S.B., Kitayama Y., Ishiura M., Golden S.S., Kondo T.
      Cell 101:223-233(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH SASA.
    7. "Two KaiA-binding domains of cyanobacterial circadian clock protein KaiC."
      Taniguchi Y., Yamaguchi A., Hijikata A., Iwasaki H., Kamagata K., Ishiura M., Go M., Kondo T.
      FEBS Lett. 496:86-90(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH KAIA, MUTANTS KAIC3; KAIC6; KAIC11 AND KAIC12.
    8. "KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria."
      Iwasaki H., Nishiwaki T., Kitayama Y., Nakajima M., Kondo T.
      Proc. Natl. Acad. Sci. U.S.A. 99:15788-15793(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION, ENZYME REGULATION, MUTANT KAIC15.
    9. "Circadian clock protein KaiC forms ATP-dependent hexameric rings and binds DNA."
      Mori T., Saveliev S.V., Xu Y., Stafford W.F., Cox M.M., Inman R.B., Johnson C.H.
      Proc. Natl. Acad. Sci. U.S.A. 99:17203-17208(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: HEXAMERIZATION, DNA-BINDING, ATP-BINDING.
    10. "Cyanobacterial circadian clockwork: roles of KaiA, KaiB and the kaiBC promoter in regulating KaiC."
      Xu Y., Mori T., Johnson C.H.
      EMBO J. 22:2117-2126(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: ENZYME REGULATION, PHOSPHORYLATION, INTERACTION WITH KAIB.
    11. "KaiB functions as an attenuator of KaiC phosphorylation in the cyanobacterial circadian clock system."
      Kitayama Y., Iwasaki H., Nishiwaki T., Kondo T.
      EMBO J. 22:2127-2134(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: ENZYME REGULATION, PHOSPHORYLATION, INTERACTION WITH KAIB.
    12. "Global gene repression by KaiC as a master process of prokaryotic circadian system."
      Nakahira Y., Katayama M., Miyashita H., Kutsuna S., Iwasaki H., Oyama T., Kondo T.
      Proc. Natl. Acad. Sci. U.S.A. 101:881-885(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION OF THE KAIABC COMPLEX, INDUCTION.
    13. "Stoichiometric interactions between cyanobacterial clock proteins KaiA and KaiC."
      Hayashi F., Ito H., Fujita M., Iwase R., Uzumaki T., Ishiura M.
      Biochem. Biophys. Res. Commun. 316:195-202(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: STOICHIOMETRY OF THE COMPLEX FORMED WITH KAIA.
    14. "Circadian rhythms in the synthesis and degradation of a master clock protein kaiC in cyanobacteria."
      Imai K., Nishiwaki T., Kondo T., Iwasaki H.
      J. Biol. Chem. 279:36534-36539(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: DEVELOPMENTAL STAGE.
    15. "Visualizing a circadian clock protein; crystal structure of kaiC and functional insights."
      Pattanayek R., Wang J., Mori T., Xu Y., Johnson C.H., Egli M.
      Mol. Cell 15:375-388(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF HEXAMER, COFACTOR, MUTAGENESIS OF THR-432.

    Entry informationi

    Entry nameiKAIC_SYNE7
    AccessioniPrimary (citable) accession number: Q79PF4
    Secondary accession number(s): Q31NX3, Q9Z3H2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 11, 2004
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 97 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    'Kai' means 'cycle' in Japanese.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3