Q79G13 (Q79G13_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
POSSIBLE CELLULASE CELA1 (ENDOGLUCANASE) (ENDO-1,4-BETA-GLUCANASE) (FI-CMCASE) (CARBOXYMETHYL CELLULASE) EMBL CAE55238.1
EC=3.2.1.4 EMBL CAE55238.1

Gene names

Name:	celA1 EMBL CAE55238.1
Ordered Locus Names:	Rv0062

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	380 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Glycosidase EMBL CAE55238.1 Hydrolase
Technical term	3D-structure PDB 1UOZ PDB 1UP0 PDB 1UP2 PDB 1UP3 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellulose catabolic process Inferred from direct assay Ref.2. Source: MTBBASE
Cellular component	extracellular region Inferred from direct assay. Source: MTBBASE
Molecular function	cellulase activity Inferred from direct assay Ref.2. Source: MTBBASE
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	168	1	Glucose PDB 1UOZ
	Binding site	206	1	Glucose PDB 1UOZ
	Binding site	277	1	Glucose PDB 1UOZ
	Binding site	319	1	Glucose PDB 1UOZ

Sequences

	Sequence		Length	Mass (Da)
	Q79G13 [UniParc]. Last modified July 5, 2004. Version 1. Checksum: AAA8F1BD10C4CB68	FASTA	380	39,974
	10 20 30 40 50 60 MTRRTGQRWR GTLPGRRPWT RPAPATCRRH LAFVELRHYF ARVMSSAIGS VARWIVPLLG 70 80 90 100 110 120 VAAVASIGVI ADPVRVVRAP ALILVDAANP LAGKPFYVDP ASAAMVAARN ANPPNAELTS 130 140 150 160 170 180 VANTPQSYWL DQAFPPATVG GTVARYTGAA QAAGAMPVLT LYGIPHRDCG SYASGGFATG 190 200 210 220 230 240 TDYRGWIDAV ASGLGSSPAT IIVEPDALAM ADCLSPDQRQ ERFDLVRYAV DTLTRDPAAA 250 260 270 280 290 300 VYVDAGHSRW LSAEAMAARL NDVGVGRARG FSLNVSNFYT TDEEIGYGEA ISGLTNGSHY 310 320 330 340 350 360 VIDTSRNGAG PAPDAPLNWC NPSGRALGAP PTTATAGAHA DAYLWIKRPG ESDGTCGRGE 370 380 PQAGRFVSQY AIDLAHNAGQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Mycobacterium tuberculosis strains possess functional cellulases." Varrot A., Leydier S., Pell G., Macdonald J.M., Stick R.V., Henrissat B., Gilbert H.J., Davies G.J. J. Biol. Chem. 280:20181-20184(2005) [PubMed: 15824123] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.10 ANGSTROMS) OF 88-380 IN COMPLEX WITH GLUCOSE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842572 Genomic DNA. Translation: CAE55238.1.
PIR	G70847.
RefSeq	YP_177689.1. NC_000962.2.
3D structure databases
ProteinModelPortal	Q79G13.
SMR	Q79G13. Positions 88-380.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000000800; EBMYCP00000000800; EBMYCG00000000800.
GeneID	887007.
GenomeReviews	Gene locus Rv0062 in contig AL123456_GR.
KEGG	mtu:Rv0062.
PATRIC	18148631. VBIMycTub87468_0069.
Organism-specific databases
TubercuList	Rv0062.
Phylogenomic databases
GeneTree	EBGT00050000017719.
HOGENOM	HBG485256.
OMA	AYLWVKR.
ProtClustDB	CLSK799683.
Family and domain databases
InterPro	IPR016288. Beta_cellobiohydrolase. [Graphical view]
Gene3D	G3DSA:3.20.20.40. Glyco_hydro_6. 1 hit.
KO	K01179.
Pfam	PF01341. Glyco_hydro_6. 1 hit. [Graphical view]
PIRSF	PIRSF001100. Beta_cellobiohydrolase. 1 hit.
PRINTS	PR00733. GLHYDRLASE6.
SUPFAM	SSF51989. Glyco_hydro_6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q79G13_MYCTU

Accession

Primary (citable) accession number: Q79G13

Entry history

Integrated into UniProtKB/TrEMBL:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)