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Q793U7 (B3GL1_MUSSI) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
Short name=Beta-1,3-GalNAc-T1
EC=2.4.1.79
Alternative name(s):
Beta-1,3-galactosyltransferase 3
Short name=Beta-1,3-GalTase 3
Short name=Beta3Gal-T3
Short name=Beta3GalT3
Short name=b3Gal-T3
Beta-3-Gx-T3
Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase
Globoside synthase
UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
Gene names
Name:B3galnt1
Synonyms:B3galt3, B3gt3
OrganismMus spicilegus (Steppe mouse)
Taxonomic identifier10103 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transfers N-acetylgalactosamine onto globotriaosylceramide By similarity.

Catalytic activity

UDP-N-acetyl-alpha-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.

Cofactor

Magnesium By similarity.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Golgi apparatus membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the glycosyltransferase 31 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
PRO_0000219155

Regions

Topological domain1 – 2020Cytoplasmic Potential
Transmembrane21 – 4323Helical; Signal-anchor for type II membrane protein; Potential
Topological domain44 – 331288Lumenal Potential

Amino acid modifications

Glycosylation721N-linked (GlcNAc...) Potential
Glycosylation1541N-linked (GlcNAc...) Potential
Glycosylation1981N-linked (GlcNAc...) Potential
Glycosylation2121N-linked (GlcNAc...) Potential
Glycosylation3261N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q793U7 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 387E8B0C75FC282D

FASTA33139,371
        10         20         30         40         50         60 
MAPAVLTALP NRMSLRSLKW SLLLLSLLSF LVIWYLSLPH YNVIERVNWM YFYEYEPIYR 

        70         80         90        100        110        120 
QDFRFTLREH SNCSHQNPFL VILVTSRPSD VKARQAIRVT WGEKKSWWGY EVLTFFLLGQ 

       130        140        150        160        170        180 
QAEREDKTLA LSLEDEHVLY GDIIRQDFLD TYNNLTLKTI MAFRWVMEFC PNAKYIMKTD 

       190        200        210        220        230        240 
TDVFINTGNL VKYLLNLNHS EKFFTGYPLI DNYSYRGFFH KNHISYQEYP FKVFPPYCSG 

       250        260        270        280        290        300 
LGYIMSGDLV PRVYEMMSHV KPIKFEDVYV GICLNLLKVD IHIPEDTNLF FLYRIHLDVC 

       310        320        330 
QLRRVIAAHG FSSKEIITFW QVMLRNTTCH Y

« Hide

References

[1]"Conspicuous differences among gene genealogies of 21 nuclear genes of five Mus musculus subspecies."
Liu Y., Kitano T., Koide T., Shiroishi T., Moriwaki K., Saitou N.
Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ZBN.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB039163 Genomic DNA. Translation: BAB68687.1.

3D structure databases

ProteinModelPortalQ793U7.
ModBaseSearch...

Proteomic databases

PRIDEQ793U7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG101817.

Enzyme and pathway databases

UniPathwayUPA00378.

Family and domain databases

InterProIPR002659. Glyco_trans_31.
[Graphical view]
PANTHERPTHR11214. PTHR11214. 1 hit.
PfamPF01762. Galactosyl_T. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3GL1_MUSSI
AccessionPrimary (citable) accession number: Q793U7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: July 5, 2004
Last modified: March 6, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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