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Q793U7

- B3GL1_MUSSI

UniProt

Q793U7 - B3GL1_MUSSI

Protein

UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

Gene

B3galnt1

Organism
Mus spicilegus (Steppe mouse)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (05 Jul 2004)
      Previous versions | rss
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    Functioni

    Transfers N-acetylgalactosamine onto globotriaosylceramide.By similarity

    Catalytic activityi

    UDP-N-acetyl-alpha-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = UDP + N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide.

    Cofactori

    Magnesium.By similarity

    Pathwayi

    GO - Molecular functioni

    1. galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity Source: UniProtKB-EC
    2. galactosyltransferase activity Source: InterPro

    GO - Biological processi

    1. protein glycosylation Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    UniPathwayiUPA00378.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC:2.4.1.79)
    Short name:
    Beta-1,3-GalNAc-T1
    Alternative name(s):
    Beta-1,3-galactosyltransferase 3
    Short name:
    Beta-1,3-GalTase 3
    Short name:
    Beta3Gal-T3
    Short name:
    Beta3GalT3
    Short name:
    b3Gal-T3
    Beta-3-Gx-T3
    Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase
    Globoside synthase
    UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
    Gene namesi
    Name:B3galnt1
    Synonyms:B3galt3, B3gt3
    OrganismiMus spicilegus (Steppe mouse)
    Taxonomic identifieri10103 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi membrane Source: UniProtKB-SubCell
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Golgi apparatus, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 331331UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1PRO_0000219155Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi154 – 1541N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi198 – 1981N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi212 – 2121N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi326 – 3261N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PRIDEiQ793U7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ793U7.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2020CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini44 – 331288LumenalSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei21 – 4323Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 31 family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOVERGENiHBG101817.

    Family and domain databases

    InterProiIPR002659. Glyco_trans_31.
    [Graphical view]
    PANTHERiPTHR11214. PTHR11214. 1 hit.
    PfamiPF01762. Galactosyl_T. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q793U7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPAVLTALP NRMSLRSLKW SLLLLSLLSF LVIWYLSLPH YNVIERVNWM    50
    YFYEYEPIYR QDFRFTLREH SNCSHQNPFL VILVTSRPSD VKARQAIRVT 100
    WGEKKSWWGY EVLTFFLLGQ QAEREDKTLA LSLEDEHVLY GDIIRQDFLD 150
    TYNNLTLKTI MAFRWVMEFC PNAKYIMKTD TDVFINTGNL VKYLLNLNHS 200
    EKFFTGYPLI DNYSYRGFFH KNHISYQEYP FKVFPPYCSG LGYIMSGDLV 250
    PRVYEMMSHV KPIKFEDVYV GICLNLLKVD IHIPEDTNLF FLYRIHLDVC 300
    QLRRVIAAHG FSSKEIITFW QVMLRNTTCH Y 331
    Length:331
    Mass (Da):39,371
    Last modified:July 5, 2004 - v1
    Checksum:i387E8B0C75FC282D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB039163 Genomic DNA. Translation: BAB68687.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB039163 Genomic DNA. Translation: BAB68687.1 .

    3D structure databases

    ProteinModelPortali Q793U7.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q793U7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG101817.

    Enzyme and pathway databases

    UniPathwayi UPA00378 .

    Family and domain databases

    InterProi IPR002659. Glyco_trans_31.
    [Graphical view ]
    PANTHERi PTHR11214. PTHR11214. 1 hit.
    Pfami PF01762. Galactosyl_T. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Conspicuous differences among gene genealogies of 21 nuclear genes of five Mus musculus subspecies."
      Liu Y., Kitano T., Koide T., Shiroishi T., Moriwaki K., Saitou N.
      Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ZBN.

    Entry informationi

    Entry nameiB3GL1_MUSSI
    AccessioniPrimary (citable) accession number: Q793U7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2005
    Last sequence update: July 5, 2004
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3