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Protein
Submitted name:

MCG140784

Gene

Try10

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-1442490. Collagen degradation.
R-MMU-1592389. Activation of Matrix Metalloproteinases.
R-MMU-196741. Cobalamin (Cbl, vitamin B12) transport and metabolism.
R-MMU-6798695. Neutrophil degranulation.
R-MMU-6803157. Antimicrobial peptides.

Protein family/group databases

MEROPSiS01.059.

Names & Taxonomyi

Protein namesi
Submitted name:
MCG140784Imported
Submitted name:
Protein Try10Imported
Submitted name:
Trypsin 10Imported
Submitted name:
Trypsinogen 10Imported
Gene namesi
Name:Try10Imported
Synonyms:Tcrb-V20Imported, trypsinogenImported
ORF Names:mCG_140784Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:3687012. Try10.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000071521.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071976.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 244Peptidase S1InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation
Contains 1 peptidase S1 domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118862.
HOGENOMiHOG000251820.
HOVERGENiHBG013304.
KOiK01312.
OMAiPAINSKF.
OrthoDBiEOG091G0DF7.
TreeFamiTF331065.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiIPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q792Z1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLLFLALV GAAVAFPVDD DDKIVGGYTC RENSVPYQVS LNSGYHFCGG
60 70 80 90 100
SLINDQWVVS AAHCYKSRIQ VRLGEHNINV LEGNEQFIDA ANIIKHPKFK
110 120 130 140 150
KKTLDNDIML IKLSSPVTLN ARVATVALPS SCAAAGTQCL ISGWGNTLSS
160 170 180 190 200
GVNNPDLLQC LDAPLLPQAD CEASYPGKIT KNMICVGFLE GGKDSCQGDS
210 220 230 240
GGPVVCNGQL QGIVSWGYGC AQKDNPGVYT KVCNYVDWIQ NTIAAN
Length:246
Mass (Da):26,221
Last modified:July 5, 2004 - v1
Checksum:i7B6A965118DDCC82
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC158659 Genomic DNA. No translation available.
AE000664 Genomic DNA. Translation: AAB69058.1.
BC138698 mRNA. Translation: AAI38699.1.
BC146017 mRNA. Translation: AAI46018.1.
AK133516 mRNA. Translation: BAE21698.1.
CH466533 Genomic DNA. Translation: EDL13535.1.
RefSeqiNP_001034085.1. NM_001038996.2.
UniGeneiMm.443385.

Genome annotation databases

EnsembliENSMUST00000072103; ENSMUSP00000071976; ENSMUSG00000071521.
GeneIDi436522.
KEGGimmu:436522.
UCSCiuc009bou.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC158659 Genomic DNA. No translation available.
AE000664 Genomic DNA. Translation: AAB69058.1.
BC138698 mRNA. Translation: AAI38699.1.
BC146017 mRNA. Translation: AAI46018.1.
AK133516 mRNA. Translation: BAE21698.1.
CH466533 Genomic DNA. Translation: EDL13535.1.
RefSeqiNP_001034085.1. NM_001038996.2.
UniGeneiMm.443385.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071976.

Protein family/group databases

MEROPSiS01.059.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000072103; ENSMUSP00000071976; ENSMUSG00000071521.
GeneIDi436522.
KEGGimmu:436522.
UCSCiuc009bou.2. mouse.

Organism-specific databases

CTDi436522.
MGIiMGI:3687012. Try10.

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118862.
HOGENOMiHOG000251820.
HOVERGENiHBG013304.
KOiK01312.
OMAiPAINSKF.
OrthoDBiEOG091G0DF7.
TreeFamiTF331065.

Enzyme and pathway databases

ReactomeiR-MMU-1442490. Collagen degradation.
R-MMU-1592389. Activation of Matrix Metalloproteinases.
R-MMU-196741. Cobalamin (Cbl, vitamin B12) transport and metabolism.
R-MMU-6798695. Neutrophil degranulation.
R-MMU-6803157. Antimicrobial peptides.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000071521.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiIPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ792Z1_MOUSE
AccessioniPrimary (citable) accession number: Q792Z1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: November 30, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.