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Protein
Submitted name:

MCG4990, isoform CRA_e

Gene

Prss2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MCG4990, isoform CRA_eImported
Submitted name:
Pancreatic trypsinImported
Submitted name:
Trypsinogen 20Imported
Gene namesi
Name:Prss2Imported
Synonyms:TaImported, trypsinogenImported
ORF Names:mCG_4990Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102759 Prss2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501194859516 – 246Sequence analysisAdd BLAST231

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiQ792Y6

Expressioni

Gene expression databases

BgeeiENSMUSG00000057163
ExpressionAtlasiQ792Y6 baseline and differential

Structurei

3D structure databases

SMRiQ792Y6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 244Peptidase S1InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
HOVERGENiHBG013304
KOiK01312
OMAiPEHSVPY
OrthoDBiEOG091G0DF7

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q792Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALLILALV GAAVAFPVDD DDKIVGGYTC RESSVPYQVS LNAGYHFCGG
60 70 80 90 100
SLINDQWVVS AAHCYKYRIQ VRLGEHNINV LEGNEQFVDS AKIIRHPNYN
110 120 130 140 150
SWTLDNDIML IKLASPVTLN ARVASVPLPS SCAPAGTQCL ISGWGNTLSN
160 170 180 190 200
GVNNPDLLQC VDAPVLPQAD CEASYPGDIT NNMICVGFLE GGKDSCQGDS
210 220 230 240
GGPVVCNGEL QGIVSWGYGC AQPDAPGVYT KVCNYVDWIQ NTIADN
Length:246
Mass (Da):26,204
Last modified:May 10, 2005 - v1
Checksum:iCEF8C97AAC2D07AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000665 Genomic DNA Translation: AAB69089.1
AB017030 Genomic DNA Translation: BAA74759.1
AK003082 mRNA Translation: BAB22554.1
CH466533 Genomic DNA Translation: EDL13530.1
RefSeqiNP_033456.1, NM_009430.2
UniGeneiMm.276926

Genome annotation databases

GeneIDi22072
KEGGimmu:22072

Similar proteinsi

Entry informationi

Entry nameiQ792Y6_MOUSE
AccessioniPrimary (citable) accession number: Q792Y6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: March 28, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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