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Protein
Submitted name:

MCG4990, isoform CRA_e

Gene

Prss2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
MCG4990, isoform CRA_eImported
Submitted name:
Pancreatic trypsinImported
Submitted name:
Putative uncharacterized proteinImported
Submitted name:
Trypsinogen 20Imported
Gene namesi
Name:Prss2Imported
Synonyms:TaImported, trypsinogenImported
ORF Names:mCG_4990Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:102759. Prss2.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiQ792Y6.

Expressioni

Gene expression databases

BgeeiENSMUSG00000057163.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000065393.

Structurei

3D structure databases

SMRiQ792Y6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 244Peptidase S1InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
HOVERGENiHBG013304.
KOiK01312.
OMAiGAHDLYR.
OrthoDBiEOG091G0DF7.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
PfamiView protein in Pfam
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.

Sequencei

Sequence statusi: Complete.

Q792Y6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSALLILALV GAAVAFPVDD DDKIVGGYTC RESSVPYQVS LNAGYHFCGG
60 70 80 90 100
SLINDQWVVS AAHCYKYRIQ VRLGEHNINV LEGNEQFVDS AKIIRHPNYN
110 120 130 140 150
SWTLDNDIML IKLASPVTLN ARVASVPLPS SCAPAGTQCL ISGWGNTLSN
160 170 180 190 200
GVNNPDLLQC VDAPVLPQAD CEASYPGDIT NNMICVGFLE GGKDSCQGDS
210 220 230 240
GGPVVCNGEL QGIVSWGYGC AQPDAPGVYT KVCNYVDWIQ NTIADN
Length:246
Mass (Da):26,204
Last modified:May 10, 2005 - v1
Checksum:iCEF8C97AAC2D07AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000665 Genomic DNA. Translation: AAB69089.1.
AB017030 Genomic DNA. Translation: BAA74759.1.
AK003082 mRNA. Translation: BAB22554.1.
CH466533 Genomic DNA. Translation: EDL13530.1.
RefSeqiNP_033456.1. NM_009430.2.
UniGeneiMm.276926.

Genome annotation databases

GeneIDi22072.
KEGGimmu:22072.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000665 Genomic DNA. Translation: AAB69089.1.
AB017030 Genomic DNA. Translation: BAA74759.1.
AK003082 mRNA. Translation: BAB22554.1.
CH466533 Genomic DNA. Translation: EDL13530.1.
RefSeqiNP_033456.1. NM_009430.2.
UniGeneiMm.276926.

3D structure databases

SMRiQ792Y6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000065393.

Proteomic databases

MaxQBiQ792Y6.

Protocols and materials databases

DNASUi22072.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22072.
KEGGimmu:22072.

Organism-specific databases

CTDi5645.
MGIiMGI:102759. Prss2.

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
HOVERGENiHBG013304.
KOiK01312.
OMAiGAHDLYR.
OrthoDBiEOG091G0DF7.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000057163.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiView protein in InterPro
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
PfamiView protein in Pfam
PF00089. Trypsin. 1 hit.
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiView protein in SMART
SM00020. Tryp_SPc. 1 hit.
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiView protein in PROSITE
PS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ792Y6_MOUSE
AccessioniPrimary (citable) accession number: Q792Y6
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 7, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.