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Protein
Submitted name:

Vpr protein

Gene

vpr

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
  4. viral entry into host cell Source: UniProtKB-KW
  5. viral penetration into host nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

ActivatorSAAS annotation

Keywords - Biological processi

Cell cycleSAAS annotation, Host-virus interactionSAAS annotation, Transcription, Transcription regulationSAAS annotation, Viral penetration into host nucleusSAAS annotation, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Submitted name:
Vpr proteinImported
Gene namesi
Name:vprImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

GO - Cellular componenti

  1. host cell nucleus Source: UniProtKB-KW
  2. intracellular Source: GOC
  3. virion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Host nucleusSAAS annotation, VirionSAAS annotation

Pathology & Biotechi

Keywords - Diseasei

AIDSUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ79237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.

Sequencei

Sequence statusi: Complete.

Q79237-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQAPEDQGP QREPYNEWTL ELLEELKNEA VRHFPRVWLH GLGQHIYETY
60 70 80 90
GDTWAGVEAI IRTLQQLLFI HFRIGCRHSR IGITPQRRTR NGASRS
Length:96
Mass (Da):11,308
Last modified:November 1, 1996 - v1
Checksum:i0385B44D40809D4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68543 Genomic DNA. Translation: CAA92867.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68543 Genomic DNA. Translation: CAA92867.1.

3D structure databases

ProteinModelPortaliQ79237.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.
ProtoNetiSearch...

Publicationsi

  1. "Consistent risk group-associated differences in human immunodeficiency virus type 1 vpr, vpu and V3 sequences despite independent evolution."
    Kuiken C.L., Cornelissen M.T.E., Zorgdrager F., Hartman S., Gibbs A.J., Goudsmit J.
    J. Gen. Virol. 77:783-792(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Kuiken L.
    Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ79237_9HIV1
AccessioniPrimary (citable) accession number: Q79237
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 4, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.