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Q791V5 (MTCH2_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mitochondrial carrier homolog 2
Gene names
Name:Mtch2
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The substrate transported is not yet known. Induces mitochondrial depolarization By similarity.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]

Contains 2 Solcar repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 303302Mitochondrial carrier homolog 2
PRO_0000090638

Regions

Transmembrane8 – 2821Helical; Potential
Transmembrane175 – 19521Helical; Potential
Transmembrane224 – 24421Helical; Potential
Repeat2 – 9897Solcar 1
Repeat118 – 20689Solcar 2

Amino acid modifications

Modified residue21N-acetylalanine By similarity

Experimental info

Sequence conflict2061Y → C in BAB27839. Ref.2
Sequence conflict2071A → T in BAB25848. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q791V5 [UniParc].

Last modified July 5, 2004. Version 1.
Checksum: 248F8A1E4CF29975

FASTA30333,499
        10         20         30         40         50         60 
MADAASQVLL GSGLTILSQP LMYVKVLIQV GYEPLPPTIG RNIFGRQVCQ LPGLFCYAQH 

        70         80         90        100        110        120 
IASIDGRRGL FTGLTPRLCS GVLGTVVHGK VLQYYQESEK PEELGSVTVQ KEYSSSFDRV 

       130        140        150        160        170        180 
IKETTREMIA RSAATLITHP FHVITLRSMV QFIGRESKYC GLCDSIVTIY REEGIVGFFA 

       190        200        210        220        230        240 
GLIPRLLGDI ISLWLCNSLA YLINTYALDS GVSTMNEMKS YSQAVTGFFA SMLTYPFVLV 

       250        260        270        280        290        300 
SNLMAVNNCG LAGGSPPYSP IYTSWIDCWC MLQKAGNMSR GNSLFFRKVP CGKTYCYDLR 


MLI 

« Hide

References

« Hide 'large scale' references
[1]"Identification of an evolutionary conserved mitochondrial carrier family from various organisms."
Jang J.S., Hahn Y., Park C., Chung J.H.
Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Heart, Hippocampus, Small intestine, Stomach, Testis and Tongue.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Mammary tumor.
[4]Lubec G., Kang S.U.
Submitted (APR-2007) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 69-77; 91-119 AND 172-185, IDENTIFICATION BY MASS SPECTROMETRY.
Strain: C57BL/6.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF176009 mRNA. Translation: AAD52647.1.
AK003100 mRNA. Translation: BAB22565.1.
AK008487 mRNA. Translation: BAB25694.1.
AK008712 mRNA. Translation: BAB25848.1.
AK011785 mRNA. Translation: BAB27839.1.
AK011874 mRNA. Translation: BAB27892.1.
AK075890 mRNA. Translation: BAC36033.1.
AK161441 mRNA. Translation: BAE36399.1.
AK164169 mRNA. Translation: BAE37660.1.
BC002152 mRNA. Translation: AAH02152.1.
BC038899 mRNA. Translation: AAH38899.1.
BC038916 mRNA. Translation: AAH38916.1.
CCDSCCDS16416.1.
RefSeqNP_062732.1. NM_019758.2.
UniGeneMm.28023.

3D structure databases

ProteinModelPortalQ791V5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid207972. 2 interactions.
IntActQ791V5. 4 interactions.
MINTMINT-1842785.
STRING10090.ENSMUSP00000107095.

PTM databases

PhosphoSiteQ791V5.

Proteomic databases

MaxQBQ791V5.
PaxDbQ791V5.
PRIDEQ791V5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000136872; ENSMUSP00000121851; ENSMUSG00000027282.
GeneID56428.
KEGGmmu:56428.
UCSCuc008ktn.1. mouse.

Organism-specific databases

CTD23788.
MGIMGI:1929260. Mtch2.

Phylogenomic databases

eggNOGNOG311439.
GeneTreeENSGT00390000000020.
HOGENOMHOG000231394.
HOVERGENHBG058632.
KOK17885.
OrthoDBEOG7966H6.
PhylomeDBQ791V5.
TreeFamTF313721.

Gene expression databases

ArrayExpressQ791V5.
BgeeQ791V5.
CleanExMM_MTCH2.
GenevestigatorQ791V5.

Family and domain databases

Gene3D1.50.40.10. 1 hit.
InterProIPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamPF00153. Mito_carr. 1 hit.
[Graphical view]
SUPFAMSSF103506. SSF103506. 1 hit.
PROSITEPS50920. SOLCAR. 2 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio312594.
PROQ791V5.
SOURCESearch...

Entry information

Entry nameMTCH2_MOUSE
AccessionPrimary (citable) accession number: Q791V5
Secondary accession number(s): Q3TPS5 expand/collapse secondary AC list , Q99LZ6, Q9D060, Q9D7Y2, Q9QZP3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: July 5, 2004
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot