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Protein

Coiled-coil domain-containing protein 25

Gene

Ccdc25

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 25
Gene namesi
Name:Ccdc25
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1914429. Ccdc25.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: MGI
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208Coiled-coil domain-containing protein 25PRO_0000233405Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei23 – 231N6-acetyllysineBy similarity
Modified residuei204 – 2041Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ78PG9.
PaxDbiQ78PG9.
PRIDEiQ78PG9.

PTM databases

PhosphoSiteiQ78PG9.

Expressioni

Gene expression databases

BgeeiQ78PG9.
CleanExiMM_CCDC25.
ExpressionAtlasiQ78PG9. baseline and differential.
GenevestigatoriQ78PG9.

Interactioni

Protein-protein interaction databases

IntActiQ78PG9. 1 interaction.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili117 – 18771Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the CCDC25 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG288654.
GeneTreeiENSGT00390000004380.
HOGENOMiHOG000041378.
HOVERGENiHBG057190.
InParanoidiQ78PG9.
OMAiPGQVAYH.
OrthoDBiEOG7PVWQT.
PhylomeDBiQ78PG9.
TreeFamiTF300013.

Family and domain databases

InterProiIPR008532. DUF814.
[Graphical view]
PfamiPF05670. DUF814. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q78PG9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFYFTSSSV NSSTYTIYMG KDKYENEDLI KYGWPEDIWF HVDKLSSAHV
60 70 80 90 100
YLRLQKGEKI EDIPKEVLMD CAHLVKANSI QGCKMNNVNV VYTPWSNLKK
110 120 130 140 150
TADMDVGQIG FHRQKDVKIV TVEKKVNEIL NRLEKTKLEK FPDLAAEKEG
160 170 180 190 200
RDREERNEKK AQIQEMKRKE KEEMKKKREM DELRSYSSLM KVENMSSNQD

GNDSDEFM
Length:208
Mass (Da):24,480
Last modified:October 25, 2004 - v1
Checksum:i60FF54684E72337F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti156 – 1561R → G in BAB30178 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012172 mRNA. Translation: BAB28076.1.
AK016286 mRNA. Translation: BAB30178.1.
AK078345 mRNA. Translation: BAC37230.1.
AK089982 mRNA. Translation: BAC41026.1.
CCDSiCCDS27217.1.
RefSeqiNP_666056.1. NM_145944.4.
UniGeneiMm.214576.

Genome annotation databases

EnsembliENSMUST00000022614; ENSMUSP00000022614; ENSMUSG00000022035.
GeneIDi67179.
KEGGimmu:67179.
UCSCiuc007ujq.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012172 mRNA. Translation: BAB28076.1.
AK016286 mRNA. Translation: BAB30178.1.
AK078345 mRNA. Translation: BAC37230.1.
AK089982 mRNA. Translation: BAC41026.1.
CCDSiCCDS27217.1.
RefSeqiNP_666056.1. NM_145944.4.
UniGeneiMm.214576.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ78PG9. 1 interaction.

PTM databases

PhosphoSiteiQ78PG9.

Proteomic databases

MaxQBiQ78PG9.
PaxDbiQ78PG9.
PRIDEiQ78PG9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022614; ENSMUSP00000022614; ENSMUSG00000022035.
GeneIDi67179.
KEGGimmu:67179.
UCSCiuc007ujq.1. mouse.

Organism-specific databases

CTDi55246.
MGIiMGI:1914429. Ccdc25.

Phylogenomic databases

eggNOGiNOG288654.
GeneTreeiENSGT00390000004380.
HOGENOMiHOG000041378.
HOVERGENiHBG057190.
InParanoidiQ78PG9.
OMAiPGQVAYH.
OrthoDBiEOG7PVWQT.
PhylomeDBiQ78PG9.
TreeFamiTF300013.

Miscellaneous databases

ChiTaRSiCcdc25. mouse.
NextBioi323808.
PROiQ78PG9.
SOURCEiSearch...

Gene expression databases

BgeeiQ78PG9.
CleanExiMM_CCDC25.
ExpressionAtlasiQ78PG9. baseline and differential.
GenevestigatoriQ78PG9.

Family and domain databases

InterProiIPR008532. DUF814.
[Graphical view]
PfamiPF05670. DUF814. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Cerebellum and Kidney.
  2. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-204, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic brain.

Entry informationi

Entry nameiCCD25_MOUSE
AccessioniPrimary (citable) accession number: Q78PG9
Secondary accession number(s): Q9CSQ8, Q9CUF8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: October 25, 2004
Last modified: March 4, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.