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Protein
Submitted name:

Acid ceramidase

Gene

Asah1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Protein family/group databases

MEROPSiC89.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Acid ceramidaseImported
Submitted name:
N-acylsphingosine amidohydrolase 1, isoform CRA_aImported
Gene namesi
Name:Asah1Imported
ORF Names:mCG_17727Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1277124. Asah1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500878319521 – 394Sequence analysisAdd BLAST374

Expressioni

Gene expression databases

BgeeiENSMUSG00000031591.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034000.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 105NAAA-betaInterPro annotationAdd BLAST62
Domaini142 – 380CBAHInterPro annotationAdd BLAST239

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFSS. Eukaryota.
ENOG410XQ6Y. LUCA.
HOVERGENiHBG050586.
KOiK12348.
OMAiWYTINLD.
OrthoDBiEOG091G08N9.

Family and domain databases

Gene3Di3.60.60.10. 1 hit.
InterProiIPR016699. Acid_ceramidase-like.
IPR029130. Acid_ceramidase_N.
IPR029132. CBAH/NAAA_C.
IPR003199. Chologlycine_hydro/PeptC59.
[Graphical view]
PfamiPF02275. CBAH. 1 hit.
PF15508. NAAA-beta. 1 hit.
[Graphical view]
PIRSFiPIRSF017632. Acid_ceramidase-like. 1 hit.

Sequencei

Sequence statusi: Complete.

Q78P93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGQSLLTWV LAAAVTCAQA QDVPPWTEDC RKSTYPPSGP TYRGPVPWHT
60 70 80 90 100
INLDLPPYKR WHELLAQKAP ALRILVNSIT SLVNTFVPSG KLMKMVDQKL
110 120 130 140 150
PGMIGSLPDP FGEEMRGIAD VTGIPLGEII SFNIFYELFT MCTSIITEDE
160 170 180 190 200
KGHLLHGRNM DFGIFLGWNI NNNTWVVTEE LKPLTVNLDF QRNNKTVFKA
210 220 230 240 250
TSFVGYVGML TGFKPGLFSL SLNERFSING GYLGILEWMF GRKDAQWVGF
260 270 280 290 300
ITRSVLENTT SYEEAKNTLT KTKIMAPVYF ILGGKKSGEG CVITRERKES
310 320 330 340 350
LDVYELDPKH GRWYVVQTNY DRWKNTLFID DRRTPAKKCL NHTTQKNLSF
360 370 380 390
ATIYDVLSTK PVLNKLTVFT TLMDVTKGQF ESHLRDCPDP CIGW
Length:394
Mass (Da):44,670
Last modified:May 10, 2005 - v1
Checksum:iDA7BFBFDC45C9F65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028080 Genomic DNA. Translation: AAK21979.1.
AF352179 mRNA. Translation: AAK39512.1.
AK075919 mRNA. Translation: BAC36053.1.
AK077721 mRNA. Translation: BAC36980.1.
AK090314 mRNA. Translation: BAC41166.1.
AK151478 mRNA. Translation: BAE30433.1.
AK166757 mRNA. Translation: BAE38998.1.
CH466554 Genomic DNA. Translation: EDL35519.1.
RefSeqiNP_062708.1. NM_019734.3.
XP_017168016.1. XM_017312527.1.
XP_017168017.1. XM_017312528.1.
XP_017168018.1. XM_017312529.1.
XP_017168019.1. XM_017312530.1.
XP_017168020.1. XM_017312531.1.
XP_017168021.1. XM_017312532.1.
UniGeneiMm.22547.

Genome annotation databases

GeneIDi11886.
KEGGimmu:11886.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028080 Genomic DNA. Translation: AAK21979.1.
AF352179 mRNA. Translation: AAK39512.1.
AK075919 mRNA. Translation: BAC36053.1.
AK077721 mRNA. Translation: BAC36980.1.
AK090314 mRNA. Translation: BAC41166.1.
AK151478 mRNA. Translation: BAE30433.1.
AK166757 mRNA. Translation: BAE38998.1.
CH466554 Genomic DNA. Translation: EDL35519.1.
RefSeqiNP_062708.1. NM_019734.3.
XP_017168016.1. XM_017312527.1.
XP_017168017.1. XM_017312528.1.
XP_017168018.1. XM_017312529.1.
XP_017168019.1. XM_017312530.1.
XP_017168020.1. XM_017312531.1.
XP_017168021.1. XM_017312532.1.
UniGeneiMm.22547.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000034000.

Protein family/group databases

MEROPSiC89.001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11886.
KEGGimmu:11886.

Organism-specific databases

CTDi427.
MGIiMGI:1277124. Asah1.

Phylogenomic databases

eggNOGiENOG410IFSS. Eukaryota.
ENOG410XQ6Y. LUCA.
HOVERGENiHBG050586.
KOiK12348.
OMAiWYTINLD.
OrthoDBiEOG091G08N9.

Miscellaneous databases

ChiTaRSiAsah1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000031591.

Family and domain databases

Gene3Di3.60.60.10. 1 hit.
InterProiIPR016699. Acid_ceramidase-like.
IPR029130. Acid_ceramidase_N.
IPR029132. CBAH/NAAA_C.
IPR003199. Chologlycine_hydro/PeptC59.
[Graphical view]
PfamiPF02275. CBAH. 1 hit.
PF15508. NAAA-beta. 1 hit.
[Graphical view]
PIRSFiPIRSF017632. Acid_ceramidase-like. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ78P93_MOUSE
AccessioniPrimary (citable) accession number: Q78P93
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 30, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.