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Protein
Submitted name:

Acid ceramidase

Gene

Asah1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Acid ceramidaseImported
Submitted name:
N-acylsphingosine amidohydrolase 1, isoform CRA_aImported
Gene namesi
Name:Asah1Imported
ORF Names:mCG_17727Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1277124 Asah1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501431081921 – 394Sequence analysisAdd BLAST374

Proteomic databases

PRIDEiQ78P93

Expressioni

Gene expression databases

BgeeiENSMUSG00000031591
ExpressionAtlasiQ78P93 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 104NAAA-betaInterPro annotationAdd BLAST61
Domaini142 – 380CBAHInterPro annotationAdd BLAST239

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFSS Eukaryota
ENOG410XQ6Y LUCA
HOVERGENiHBG050586
KOiK12348
OMAiDAMWIGF
OrthoDBiEOG091G08N9

Family and domain databases

InterProiView protein in InterPro
IPR016699 Acid_ceramidase-like
IPR029130 Acid_ceramidase_N
IPR029132 CBAH/NAAA_C
PfamiView protein in Pfam
PF02275 CBAH, 1 hit
PF15508 NAAA-beta, 1 hit
PIRSFiPIRSF017632 Acid_ceramidase-like, 1 hit

Sequencei

Sequence statusi: Complete.

Q78P93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGQSLLTWV LAAAVTCAQA QDVPPWTEDC RKSTYPPSGP TYRGPVPWHT
60 70 80 90 100
INLDLPPYKR WHELLAQKAP ALRILVNSIT SLVNTFVPSG KLMKMVDQKL
110 120 130 140 150
PGMIGSLPDP FGEEMRGIAD VTGIPLGEII SFNIFYELFT MCTSIITEDE
160 170 180 190 200
KGHLLHGRNM DFGIFLGWNI NNNTWVVTEE LKPLTVNLDF QRNNKTVFKA
210 220 230 240 250
TSFVGYVGML TGFKPGLFSL SLNERFSING GYLGILEWMF GRKDAQWVGF
260 270 280 290 300
ITRSVLENTT SYEEAKNTLT KTKIMAPVYF ILGGKKSGEG CVITRERKES
310 320 330 340 350
LDVYELDPKH GRWYVVQTNY DRWKNTLFID DRRTPAKKCL NHTTQKNLSF
360 370 380 390
ATIYDVLSTK PVLNKLTVFT TLMDVTKGQF ESHLRDCPDP CIGW
Length:394
Mass (Da):44,670
Last modified:May 10, 2005 - v1
Checksum:iDA7BFBFDC45C9F65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY028080 Genomic DNA Translation: AAK21979.1
AF352179 mRNA Translation: AAK39512.1
AK075919 mRNA Translation: BAC36053.1
AK077721 mRNA Translation: BAC36980.1
AK090314 mRNA Translation: BAC41166.1
AK151478 mRNA Translation: BAE30433.1
AK166757 mRNA Translation: BAE38998.1
CH466554 Genomic DNA Translation: EDL35519.1
RefSeqiNP_062708.1, NM_019734.3
XP_017168016.1, XM_017312527.1
XP_017168017.1, XM_017312528.1
XP_017168018.1, XM_017312529.1
XP_017168019.1, XM_017312530.1
XP_017168020.1, XM_017312531.1
XP_017168021.1, XM_017312532.1
UniGeneiMm.22547

Genome annotation databases

GeneIDi11886
KEGGimmu:11886

Similar proteinsi

Entry informationi

Entry nameiQ78P93_MOUSE
AccessioniPrimary (citable) accession number: Q78P93
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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